The Pharma Data

MAY 22, 2023

WHO launches global network to detect and prevent infectious disease threats WHO and partners are launching a global network to help protect people from infectious disease threats through the power of pathogen genomics. COVID-19 highlighted the critical role pathogen genomics plays in responding to pandemic threats.

Genome 52

Genome Genomics Bioinformatics Bacteria 52

Drug Discovery World

JULY 29, 2022

But with hundreds of bacterial species populating our gastrointestinal tract, it’s a daunting task to pinpoint which molecules made by which bacteria affect which biological processes—and how they do so. Such knowledge is essential for learning how to manipulate gut bacteria to treat or prevent illness.

Bacterium 52

Bacterium Research Bacteria Immune Response 52

Drug Discovery World

FEBRUARY 6, 2024

Verge Genomics’ potential amyotrophic lateral sclerosis (ALS) treatment VRG50635 is one of the first drugs to enter clinical trials that was entirely discovered and developed using an AI-enabled platform 6. In June 2023, lab automation company Opentrons launched its Flex robots for scientists using generative AI. Obulytix is not alone.

Marketing 69

Marketing Medicine Genome Genomics 69

The Pharma Data

JULY 11, 2021

We are talking about the microbiome – the vast collection of bacteria in the human gut. The microbiome has been the focus of research for 20 years – ever since a new technique made it possible to analyse these bacteria quickly and precisely: high-throughput sequencing. The immune system is mentioned particularly frequently.

Bacteria 52

Bacteria Genetics Regulation Scientist 52

XTalks

NOVEMBER 3, 2023

CRISPR works as genetic scissors to edit parts of the genome. The CRISPR-Cas9 gene editing system was first discovered to be endogenous in bacteria. The companies used data from the 1,000 Genomes Project but from that, only 61 datasets made the cut to encompass the ideal patient population. “I

Gene Therapy 59

Gene Therapy Gene Gene Editing In-Vivo 59

pharmaphorum

SEPTEMBER 14, 2020

Here he gives us a deeper look at how genomic medicine is evolving and the barriers that are preventing it from reaching its full potential. I saw this, in particular, with the finishing of the human genome,” says Charlie. “At In reality, finishing the human genome was the first step of what is a long journey.”.

Genome 116

Genome Genomics Medicine Gene 116

Drug Discovery World

MAY 6, 2024

Mazzetti and Schneider give the example of T3 Pharmaceuticals, a University of Basel spin-off that developed a proprietary cancer therapy platform based on regulating and harnessing the natural behaviours of live bacteria. This knowledge base will accelerate the sector and encourage new companies.

Drugs 59

Drugs Life Science Gene Editing Gene 59

XTalks

DECEMBER 24, 2020

From isolating SARS-CoV-2 in early January to sequencing its genome shortly thereafter and having a prototype vaccine against it within days, scientific process and progress have held steadfast throughout the pandemic. CRISPR are found in approximately 50 percent of sequenced bacterial genomes and nearly 90 percent of archaea genomes.

Life Science 111

Life Science Vaccination Vaccine Gene 111

Drug Discovery World

AUGUST 10, 2022

The immune system typically identifies foreign entities such as bacteria and viruses and activates lymphocytes such as T cells to destroy them with overwhelming force. To overcome the challenge of identifying the ideal target, scientists are using several creative methods. The challenge of manufacturing CAR T cells.

Manufacturing 98

Manufacturing Gene Genome Genomics 98

Drug Discovery World

MAY 2, 2023

In an effort to defend themselves against viral infection, bacterial cells capture and copy DNA fragments of bacteriophages into their genome. In the event of an attack from similar bacteriophages, the bacteria can recognise these segments and use this to discern and cleave the viral DNA, which disrupts the viral gene function.

Genome 52

Genome Genomics Gene DNA 52

Drug Discovery World

OCTOBER 4, 2022

Rebecca McClellan, Scientific Program Manager, Research, Development & Communications, explains how scientists are learning more about the connections between the microbiome and human health to potentially develop first-in-class microbiome therapies. They introduced hCom1 to mice that are carefully designed to have no bacteria present.

Research 52

Research Bacteria Scientist Bacterium 52

Drug Discovery World

JULY 18, 2023

Rolf Turk , Senior Manager, Genomics Medicine at Integrated DNA Technologies, examines how CRISPR is being used to enhance cancer therapies. Herpesviridae, Polyomaviridae, and Papillomaviridae), bacteria (e.g., CRISPR diagnostics have successfully detected various pathogens, including RNA viruses (eg.

DNA 98

DNA Genome Genomics RNA 98

Drug Discovery World

APRIL 25, 2024

For instance, bacteria and yeast cell lines are easier to cultivate compared with mammalian cell lines, requiring less maintenance for the medium they are grown in. Recent years have also seen the development of technologies that enable a better genomic and transcriptomic analysis of single cells.

Development 59

Development Protein In-Vivo Life Science 59

Drug Discovery World

APRIL 30, 2024

Proteins perform myriad functions within the human body and scientists have estimated that there are at least 20,000 canonical proteins that we know about. If the body fails to make the right protein, diseases such as cancer, type II diabetes, neurological conditions, and metabolic diseases can occur.

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RNA Protein Vaccination Vaccine 52