Pharmaceutical Technology

JUNE 20, 2023

The new AIID building will include a human infection challenge unit, high-containment facilities, a robotic biobanking facility, interview rooms, dry laboratories and spaces for community engagement and co-design work. It will be connected across multiple levels to the University of Melbourne’s Doherty Institute.

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Biobanking Genome Genomics Clinical Trials 130

Drug Discovery World

JANUARY 29, 2024

Utilising diverse data in clinical trials for drug discovery: Key speakers from pharma and industry discussed the integration of diverse data in clinical trials, emphasising its role in accelerating drug discovery processes for more effective and personalised treatments.

Genome 59

Genome Genomics Medicine Biobanking 59

pharmaphorum

JANUARY 18, 2023

Pharmaceutical companies and biotechs are also adapting their approaches, launching patient finding and engagement programmes that can start years before clinical trials begin and allow them to run ‘recontact by genotype’ studies that the Resilience Project would have liked to do. Giving participants something in return.

Genetic Disease 80

Genetic Disease Genetics Research Genome 80

Drug Discovery World

MARCH 20, 2024

Around 30% of drugs show adverse reactions during human clinical trials despite promising pre-clinical studies. This signifies the technology’s potential to de-risk drug development by ensuring only the most clinically relevant leads advance to clinical trials. Backed by the FDA Modernization Act 2.0,

Research 59

Research Clinical Trials Clinical Trials In-Vivo 59

The Pharma Data

JANUARY 31, 2021

“You might not see it immediately because many of these larger companies happen to also have their own internal biobanks, so they are not entirely reliant on primary acquisition of samples on the outside,” Ianelli said. I think it’s also important to think about the definition of biobanks. These are banks.

Research 52

Research Biobanking Clinical Trials Clinical Trials 52

The Pharma Data

JULY 8, 2021

Managed by the Broad Institute of MIT and Harvard, the browser gives access to results from analyses of whole exome sequencing data from 300,000 UK Biobank research participants. (Nasdaq: BIIB) and Pfizer (NYSE: PFE). These genetic data have been paired with detailed health information to create this browsable resource.

Genetics 52

Genetics Biobanking Protein Containment 52

Drug Discovery World

OCTOBER 30, 2023

We previously conducted a hypothesis-free study using genotype data from the UK Biobank, which resulted in the first mechanism-based stratification of endometriosis patients. Are drug repurposing strategies possible and can clinical trial outcomes be improved through more targeted recruitment methods?

Genome 72

Genome Genomics Genotype Clinical Trials 72

XTalks

FEBRUARY 4, 2021

Generation of strong research dataset cohorts must begin with high-quality clinical samples. Biobanks are used for the coordination of high-yield patient sample collection. There are a number of complexities associated with the collection, banking and distribution of clinical samples. Biobanking Models. Dr. Gordon R.

Research 98

Research Biobanking Drugs Genome 98

pharmaphorum

NOVEMBER 24, 2022

More than two years on, the EU medicines regulator has now selected the first set of data partners to collaborate with DARWIN EU, which focuses on real-world evidence collected on a patient’s health status or delivery of healthcare from a variety of sources, other than conventional clinical trials.

Big Data 52

Big Data Biobanking Regulation Medicine 52

Drug Discovery World

APRIL 20, 2023

Structural MRI data from the UK Biobank cohort found reductions in global brain size, particularly reduced grey matter thickness in the orbitofrontal cortex and parahippocampal gyrus, among participants who had had Covid-19, an average of 141 days before scanning 11. 2020, doi: 10.1016/j. 2020.08.028. G Douaud et al., 697–707, Apr.

Development 98

Development Drugs Clinical Trials Clinical Trials 98

The Pharma Data

AUGUST 30, 2021

MADRID-COVID is a randomized clinical trial conducted in close collaboration between the CNIC and cardiology, ICU, pulmonology, and biobank services at FJD Hospital. Given the central role played by neutrophils in ARDS, the team postulated that metoprolol might be an effective treatment for patients with severe COVID-19.

Drugs 52

Drugs Cardiology Clinical Trials Clinical Trials 52

Drug Discovery World

JANUARY 24, 2024

Can you elaborate on the clinical timeline for these small molecules? Fibrocor is on track to complete all IND-enabling work to support IND filing and initiation of clinical trials in 2024. He has been responsible for all aspects of drug discovery, preclinical research, CM&C, Phase I and Phase II clinical trials.

Research 59

Research Gene Expression Drugs Development 59

The Pharma Data

APRIL 11, 2023

BAY 2927088 is a reversible small molecule inhibitor that is currently being evaluated in a first-in-human, Phase 1 clinical trial in non-small cell lung cancer (NSCLC) patients with mutations in epidermal growth factor receptors (EGFR & HER2) including exon20 insertions and point mutations.

Research 40

Research Clinical Trials Clinical Trials Trials 40

Advarra

FEBRUARY 13, 2024

SSO-enabled collaborative platforms allow multiple staff members to update data and documents at the same time, while allowing the site to maintain a level of security and control access to those docs.

Compliance 52

Compliance Clinical Research Research Biobanking 52

Cloudbyz

NOVEMBER 9, 2021

Is it now stored in a biobank? Whether you’re managing the biosamples of people in a clinical trial or managing the biosamples taken from people for potential and as-yet-unspecified projects, consent forms are part and parcel of the consent process in Human Biosample Management. Is the sample being transported? Timely eConsent.

Biobanking 80

Biobanking Contamination Life Science Packaging 80

The Pharma Data

JULY 12, 2021

. “In head-to-head comparisons, we demonstrated the superiority of this approach over existing methodologies to accurately predict ‘winners’ and ‘losers’ in clinical trials,” said Ghosh. HUMANOID Center of Research Excellence? .”

Drugs 52

Drugs Gene Expression Big Data Gene 52

Roots Analysis

SEPTEMBER 18, 2023

While some biobanks ( especially non-clinical ones ) use mechanical freezers for storage, liquid nitrogen is one of the most reliable cryostorage mediums.

Engineer 52

Engineer Containment In-Vivo Production 52

pharmaphorum

JULY 5, 2022

Notable highlights include the central role the UK has played in the field of genomics, with over 500 thousand patients now in the biobank, and the recent RECOVERY trial – the world’s largest clinical trial into treatments for Covid-19, with more than 40,000 participants across 185 trial sites in the UK.

Life Science 95

Life Science Biobanking Medicine Marketing 95

XTalks

APRIL 15, 2021

Late-stage clinical trial failures are largely to blame for the lack of effective treatment options for patients with HFpEF, and poor five-year survival rates make this an area of great unmet need. A lack of efficacy is the greatest reason for clinical trial failures, especially in Phase II and Phase III,” says Dr. Tyl.

Development 98

Development Drugs Genome Genomics 98

Drug Discovery World

MARCH 7, 2023

In January 2023, the company opening the second largest Biobank in the UK, which will give parents the chance to preserve their stem cells within the North West and the provision of non-invasive, prenatal testing and pregnancy testing, something that Dr Kenny hopes “can be a real catalyst for female well-being for decades to come”.

Life Science 98

Life Science DNA Clinical Development Development 98