Drug Discovery World

OCTOBER 3, 2023

Earlier this year, DDW hosted a webinar, ‘A comprehensive guide to using adeno-associated virus (AAV) vectors in gene therapy’, supported by Azenta Life Sciences. AAV is optimal for gene therapy due to its efficiency and safety in humans; however, AAV processes can present obstacles for researchers.

Gene Therapy 52

Gene Therapy Gene Life Science Bioinformatics 52

Scienmag

JANUARY 13, 2021

International Ukraine Genetic Diversity Project finds a quarter of the genetic variation in Europe, dramatically increasing information on population diversity and medical genetic variation Credit: Oakland University Today, the largest study of genetic diversity in Ukraine was published in the open science journal GigaScience.

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Genome Genomics Genetics Research 98

Drug Discovery World

MAY 16, 2023

New South African company NewBiologix has launched with the aim of developing a proprietary and breakthrough platform for the advanced engineering of cell lines used to manufacture gene and cell therapies. NewBiologix is currently focused on recombinant adeno-associated virus (rAAV) vectors, the preferred delivery vehicle for gene therapies.

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Production Gene Therapy Gene Bioinformatics 52

pharmaphorum

AUGUST 10, 2021

The three-year project – led by respiratory medicine expert Dr Timothy Hinks from the Oxford University Respiratory Medicine Unit – will use whole-genome sequencing of around 500 patients with severe asthma, comparing their gene sequences with control subjects who don’t have asthma.

Gene Sequencing 116

Gene Sequencing Bioinformatics Gene Genome 116

XTalks

JULY 19, 2021

Phosphorus, a leading preventative genomics company, has developed the first comprehensive preventative genetic test for consumers. Like other consumer genomic tests, the Phosphorus GeneCompass test also involves the collection of saliva samples that consumers send to the Phosphorus lab located in Secaucus, NJ for analysis.

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Genetics Genome Genomics Gene 98

Scienmag

MARCH 22, 2021

Using genomics, the team tracked DNA changes occurring in melanoma samples donated by patients as their disease progressed, right through to the time the patient died. […].

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DNA Genome Genomics Research 96

Drug Discovery World

NOVEMBER 30, 2023

Genomics company Broken String Biosciences has expanded its senior leadership team with the appointments of Vincent Smith as Chief Technology Officer, Jessica Rich as VP Business Development, and Gavin Burns as Vice President of Quality and Operations. Enhanc3D Genomics has appointed Hazel Jones as its new Chief Operating Officer.

Drugs 52

Drugs Genome Genomics Bioinformatics 52

Scienmag

DECEMBER 16, 2020

15, 2020 — The Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has identified a specific genetic target that could help explain the tremendous variation in how sick those infected with COVID-19 become. Comparative analysis of human and animal coronaviruses strains implicates miR1307 PHOENIX, Ariz.

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Gene Genome Genomics Genetics 40

Drug Discovery World

OCTOBER 26, 2023

The technologies cover the whole range of biomolecules from genes to protein to metabolites. While we are using standard commercially available processes for genomics, we have invested massively into high-throughput and high-resolution transcriptomics, proteomics, and metabolomics methods.

Drugs 52

Drugs Protein Genome Genomics 52

pharmaphorum

SEPTEMBER 14, 2020

Here he gives us a deeper look at how genomic medicine is evolving and the barriers that are preventing it from reaching its full potential. I saw this, in particular, with the finishing of the human genome,” says Charlie. “At In reality, finishing the human genome was the first step of what is a long journey.”.

Genome 119

Genome Genomics Medicine Gene 119

Scienmag

APRIL 23, 2021

Dr. Nils Stein will be awarded a medal from the Royal Physiographical Society in Lund for his significant and pioneering contributions to the field of cereal genomics,” explains Prof. Credit: IPK Leibniz Institute/ Andreas Bähring “Prof.

Scientist 64

Scientist Genome Genomics Bioinformatics 64

Scienmag

NOVEMBER 12, 2020

In a study that has unprecedented implications to advance both medicine and biodiversity conservation, researchers have sequenced 131 new placental mammal genomes, bringing the worldwide total to more than 250 In a study that has unprecedented implications to advance both medicine and biodiversity conservation, researchers have sequenced 131 new placental (..)

Biobanking 41

Biobanking Medicine Genome Genomics 41

pharmaphorum

JANUARY 19, 2022

The process enables researchers to examine the transcriptome – the sum total of all the messenger RNA molecules expressed from the genes of an organism – of individual cells, which gives them information that might otherwise escape scrutiny. Developments in the sector have already led to significant scientific breakthroughs.

RNA 72

RNA Research Life Science Bioinformatics 72

Roots Analysis

AUGUST 28, 2022

Recent advances in multi-omics approaches, including genomics, transcriptomics, proteomics, metabolomics, cytometry and imaging, in combination with bioinformatics and biostatistics, have been translated into several popular bioanalytical platforms, such as next-generation sequencing (NGS), single-cell analysis, flow cytometry and mass spectrometry.

Genome 52

Genome Genomics RNA Genome Project 52

Drug Discovery World

JULY 26, 2023

With 100-fold the number of genes in the human genome 1 , this microbial collection is a rich genetic signature of clinical significance that we have only recently gained the tools to explore. By Katie Gillette , Senior Project Leader, Eliza French , Analyst, and Graham Friedman , Analyst, DeciBio.

Medicine 52

Medicine Genome Genomics Bioinformatics 52

Drug Discovery World

JULY 11, 2023

Now, with the growth of publicly available genomics, transcriptomics, and proteomics databases, the ability to quickly carry out large-scale DNA, RNA, and protein screenings, and the availability of massive sets of de-identified patient data, the amount of high-value, analysable data has reached enormous proportions.

Big Data 40

Big Data Development Life Science Drugs 40

The Pharma Data

SEPTEMBER 11, 2021

This precise and rational approach to library fabrication combined with sophisticated bioinformatics and software expertise expedites antibody discovery by decreasing risk, increasing speed, and lowering the failure rate for antibody therapeutic development. About Twist Bioscience Corporation.

Antibody 52

Antibody DNA Containment Manufacturing 52

XTalks

NOVEMBER 7, 2022

These tumor-derived entities are used to derive genomic and proteomic data. Such information can reveal details about tumor staging, tumor progression, heterogeneity, gene mutations and clonal evolution. Detection of Genomic Alterations from cfDNA: Targeted, Non-Personalized Approaches. percent show less reliability).

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Clinical Trials Clinical Trials Trials FDA Approval 98

Drug Discovery World

APRIL 14, 2023

He is being recognised for his revolutionary contributions to developing the first gene-edited cell-based therapy for cancer that involves the genetic re-engineering of a patient’s own T cells to combat their disease, and for demonstrating that adoptive T-cell therapy can induce remission and in some cases cure patients with advanced cancer.

Genetics 52

Genetics Research Medicine Clinical Research 52

Drug Discovery World

JULY 29, 2022

Scientists modelling the cancer-suppressing p53 gene identify how the 20 different molecules unique to elephants get activated for increased sensitivity and response against carcinogenic conditions – with implications for cancer treatments in humans. The post Could elephant genes hold the key to avoiding cancers?

Gene 52

Gene DNA Protein Genetics 52

Drug Discovery World

APRIL 29, 2024

Jean-Baptiste Agnus, Chief Business Officer, and Peter Carbone, Chief Quality Officer, KBI Biopharma: Agnus brings more than two decades of experience in the biopharmaceutical industry with expertise in biologics, small molecule APIs, antibody-drug conjugates (ADCs), and cell and gene therapies.

Drugs 52

Drugs Sales Gene Therapy Life Science 52

Drug Discovery World

APRIL 14, 2023

At the beginning of 2023, proteomics company Nautilus Biotechnology announced a partnership with the Translational Genomics Research Institute (TGen), to study the specific proteins at work in the rare and often fatal childhood cancer, diffuse intrinsic pontine glioma (DIPG).

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Protein Genome Genomics DNA 52

XTalks

DECEMBER 13, 2023

This impressive growth can be attributed to Fulgent’s distinctive chemistries and advanced proprietary bioinformatics pipeline, which have been instrumental in fueling the company’s rapid advancement in recent years.

Genetics 111

Genetics Vaccination Vaccine DNA 111

Drug Discovery World

OCTOBER 25, 2023

I started my career in a molecular genetics diagnostics laboratory in the NHS and I remember NGS just starting to be evaluated for routine use for every sample that came into the lab, rather than us having to examine single mutations in single genes. They had to use an international collaborator to get it done and it was expensive.

Bioinformatics 115

Bioinformatics Genetics RNA Drugs 115

Drug Discovery World

FEBRUARY 6, 2023

Johannes Goll, Global Head of Emmes’ Biomedical Data Science and Bioinformatics department, explains how big data analytics can deliver improved therapies and bring clinical research one step close to realising the potential of personalised care.

Big Data 52

Big Data RNA Bioinformatics Vaccination 52

Drug Discovery World

APRIL 21, 2023

Additionally, Dr Gianni will share insights on the use of these new tools in target validation and how they might revolutionise the drug discovery paradigm.

Doctors 52

Doctors Doctor Genetics In-Vitro 52

Drug Discovery World

OCTOBER 17, 2022

For pharma and biotech companies – whether working on small or large molecule drugs, or cell and gene therapies – this means empowering scientists with better and faster data management approaches, best practices, and leading technologies so they can pinpoint new molecules and formulations and modify existing ones more easily and quickly.

Marketing 52

Marketing Scientist Gene Expression Drugs 52

Drug Discovery World

NOVEMBER 15, 2022

If you want to order gene-length sequences, rather than short oligos for PCR, the waiting times are around two or three weeks at least. Modern advances in DNA synthesis, however, have made it possible to leverage gene-to- antibody production platforms where input candidate DNA sequences can be turned into purified antibodies.

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DNA Drugs Antibody Engineer 98

The Pharma Data

JANUARY 10, 2021

I actually think neuroscience is going to heat up in 2021,” said Ben Zeskind , co-founder and CEO of Immuneering , which is using bioinformatics and computational biology to develop new drugs in this space, along with oncology and immuno-oncology. Moving on From the Amyloid Hypothesis. “I Same with Alzheimer’s.

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Vaccination Vaccine Regulation Drugs 52