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Evotec and Variant Bio partner to develop fibrosis treatments

Drug Discovery World

Evotec will identify best-in-class small molecules targeting a key fibrotic pathway with strong genetic support identified by Variant Bio and progress the programme towards the selection of a clinical development candidate(s) using its R&D platform.

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New research highlights potential of combination cancer treatmentĀ 

Drug Discovery World

iOnctura, a clinical-stage biotech developing selective cancer therapies against targets that play critical roles in multiple tumour survival pathways, has published new research data in the peer-reviewed journal Cancer Research, that supports a strategy of combining autotaxin inhibitor IOA-289 with TGF-Ī² pathway inhibitor IOA-359.

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Conversations from ESMO Targeted Anticancer Therapies Congress 2024Ā 

Drug Discovery World

DDWā€™s Megan Thomas caught up with Oliver Rausch, Chief Scientific Officer at Storm Therapeutics, following the ESMO Targeted Anticancer Therapies Congress 2024, a global meeting focusing on promising new anticancer targets and agents, focusing on those in early phase clinical development. MT: Whatā€™s next for STORMā€™s research?

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Research partners hope to develop novel antibody-drug conjugates

Drug Discovery World

Merck KGaA will be solely responsible for in vitro and in vivo characterisation, other preclinical work, and all clinical development and potential commercialisation activities relating to any resulting product candidates. . Mersana will receive an upfront payment of $30 million.

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BenevolentAI progresses drug for the potential treatment of ALSĀ 

Drug Discovery World

In preclinical studies conducted by the company, BEN-34712 was neuroprotective in a patient-derived, disease-relevant in vitro motor neuron/iAstrocyte co-culture model, demonstrating significant efficacy in both sporadic and familial subtypes of ALS.

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Immuno-Oncology Summit Europe 2023: Programme highlightsĀ 

Drug Discovery World

Key updates The findings presented by Dr Christian Klein, Head of Oncology Programs and Department Head of Cancer Immunotherapy Discovery, Roche Innovation Center Zurich, Roche Pharma Research & Early Development, pRED, bear major implications for the development of the next-generation of IL-2 therapies.

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Standigm and SK Chemicals Repurpose FDA-approved Drug into Rheumatoid Arthritis Candidate and Apply for Patent through their Open Innovation Partnership

The Pharma Data

SK Chemicals has shared their expertise in these diseases and validated the predicted targets and compounds through in vitro and in vivo studies. Further research on and development of the compound is ongoing with the objective of completing preclinical studies. About Standigm. Standigm is an AI-driven drug discovery company.