article thumbnail

What to expect from drug discovery and development in 2023

Drug Discovery World

At the height of the pandemic, DCTs were seen as a viable alternative to keeping the engines running on clinical trials when non-critical in-person care was paused. Opportunities will progress for use cases such as cancer diagnoses based on liquid biopsies, predicting cancer progression and improving gene editing tools potential (e.g.

article thumbnail

Re-assessing the risks of drug-induced arrhythmias during drug discovery

Drug Discovery World

Dofetilide was found to inhibit the human Ether-à- go-go-Related Gene (hERG) encoding cardiac potassium channel, which mediates the repolarising current in the cardiac action potential (IKr). He has a PhD in Electrical Engineering from the Engineering in Medicine Laboratory at Imperial College. He has a D.Phil.

Drugs 52