STAT News

NOVEMBER 3, 2022

… A Delaware federal court refused to throw out patent infringement claims brought by Arbutus Biopharma and Genevant Sciences against Moderna over its sale of Covid-19 vaccine doses to the U.S.  Genevant and Arbutus sued Moderna in February, seeking royalties from Moderna’s sale of its Covid-19 vaccine.

Vaccination 97

Vaccination Vaccine Drug Delivery Systems Sales 97

XTalks

FEBRUARY 21, 2022

BioNTech announced its new vaccine manufacturing approach in Africa where the company will ship modular factories, called the BioNTainer, to the continent to enable domestic production of the vaccines to help increase supplies. Related: BioNTech to Build First mRNA Vaccine Production Plant in Africa. Photo source: BioNTech.

Vaccination 105

Vaccination Vaccine Production Manufacturing 105

Drug Discovery World

MAY 19, 2023

In-human studies have been initiated to test treatments for Parkinson’s disease, radioactive contamination, Dravet Syndrome, influenza and inflammatory diseases.

Contamination 52

Contamination Clinical Trials Clinical Trials Drugs 52

pharmaphorum

AUGUST 4, 2022

Training and development. Staff development and training programmes were largely on pause during the pandemic. Businesses need to ensure they prioritise the recruitment and development of staff to help ensure longevity and survival. The post How can the pharma industry address the gap in talent recruitment and development?

Development 92

Development Manufacturing In-Vitro Compliance 92

Pharmaceutical Technology

MARCH 22, 2023

Several drug development trends are driving injectables demand. During the Covid-19 pandemic, large-scale vaccine production placed unprecedented demand on the parenteral packaging industry. This includes the rising number of biologic drugs on the market, which are mostly administered parenterally.

Contamination 130

Contamination Packaging Packaging Manufacturing 130

Pharmaceutical Technology

OCTOBER 28, 2022

It aims to ensure the quality of medicines by employing statistical, analytical, and risk-management methodology in the design, development, and manufacturing processes of medicines. Dr Amiji says that these harmonisation guidelines help industry understand the necessary requirements for developing pharmaceutical products.

Bioequivalency 130

Bioequivalency Production Branding Contamination 130

Sciensano

MARCH 27, 2024

Investigations show that these counterfeit ivermectin tablets are systematically underdosed or seriously contaminated with bacteria. This may have adverse public health implications, especially since the number of newly developed active pharmaceutical ingredients that can be safely used to control parasites is quite scarce.

Contamination 52

Contamination Bacteria Packaging Packaging 52

Pharmaceutical Technology

JULY 14, 2022

Covid-19 vaccines stay in the spotlight. Even as regulatory agencies contemplate the authorization of Omicron-specific Covid-19 vaccines , existing versions continue to make headlines. Several companies have been charged with manufacturing different components of J&J’s vaccine.

Manufacturing 130

Manufacturing Drugs Vaccination Vaccine 130

The Pharma Data

FEBRUARY 18, 2022

BioNTech SE (Nasdaq: BNTX, “BioNTech”) has taken a next step to improve vaccine supply in Africa. The company has introduced its approach to establishing scalable vaccine production by developing and delivering turnkey mRNA manufacturing facilities based on a container solution. Ugur Sahin, CEO, and Prof.

Manufacturing 40

Manufacturing Production Vaccination Vaccine 40

The Pharma Data

AUGUST 21, 2020

As the pharma community continue to research and develop hundreds of potential therapies to combat the Covid-19 pandemic, very few initiatives are yet to cross the finishing line into the commercial market. McKesson supports OWS to centralize distributor of future Covid-19 vaccines.

Vaccination 52

Vaccination Vaccine Manufacturing Contamination 52

pharmaphorum

MARCH 19, 2021

Since the third quarter of last year DeepVerge’s scientists have been working to transform an AI-based water contamination detection system into a unit that tests for the presence of the coronavirus. A femtogram is 0.000000000000000001 kilograms.

Contamination 145

Contamination Clinical Trials Clinical Trials Protein 145

Drug Discovery World

FEBRUARY 28, 2023

mRNA technology helped us to vaccinate the world against SARS-CoV-2. With only 10% of these conditions indicated for an approved therapy, there is a sizable opportunity for scientists and companies to develop treatments for patients with no other options to turn to.

Genetics 52

Genetics Genetic Analysis Vaccination Vaccine 52

Pharmaceutical Technology

JULY 22, 2022

In addition, immunity against the infection is found to wane for both previously infected individuals and the vaccinated. However, the development added to the concerns of increased monkeypox outbreaks in both the US and Canada, while confirmed cases have been reported from both Spain and Portugal, the article highlighted. Likes: 186.

Vaccination 130

Vaccination Vaccine Life Science Immune Response 130

Pharmaceutical Technology

JANUARY 12, 2023

. – about the advantages and challenges of product lyophilization, developing lyophilization processes on site at their Bloomington, Indiana plant, and the importance of continuing research. Case in point: the recently developed mRNA-based therapeutics which require cold storage for stability. Free eBook.

Production 130

Production Contamination Development Manufacturing 130

Roots Analysis

JANUARY 23, 2023

Humans to Humans Transmission: Human-to-human transmission can result from close contact with respiratory secretions, skin lesions of an infected person or recently contaminated objects. Presently, more than 25 therapeutics / vaccines are commercialized / under development for the treatment and prevention of monkeypox.

Vaccination 52

Vaccination Vaccine Contamination Development 52

The Pharma Data

DECEMBER 30, 2020

Becomes First Country to Approve Covid-19 Vaccine From Oxford-AstraZeneca. Britain became the first country to give authorization to the coronavirus vaccine developed by AstraZeneca and the University of Oxford, The New York Times reported Wednesday.

Contamination 52

Contamination Vaccination Vaccine Pharmacy 52

Drug Discovery World

JANUARY 19, 2023

pDNA is a critical raw material for advanced therapeutics including mRNA and viral vector-based cell and gene therapies and vaccines. Plasmid DNA: a critical reagent pDNA is the starting material for the development of many cell and gene therapy products, irrespective of the mode of action. billion by 2030 (BioSpace, 11 August 2022).

DNA 52

DNA Manufacturing Gene Therapy Gene 52

Pharmaceutical Technology

FEBRUARY 3, 2023

With scientists fervently developing mRNA vaccines, nucleic acid therapeutics, and viral vector-based gene therapies, clinicians are set to have a growing number of tools available to treat a wide range of conditions, from infectious diseases to genetic disorders and more. So, we set out to solve some of the problems,” she explains.

Genome 244

Genome Genomics Medicine Gene Therapy 244

The Pharma Data

AUGUST 24, 2020

There is no cure but the polio vaccine protects children for life. Polio is a virus which spreads from person to person, usually through contaminated water. A polio vaccine was developed in 1952. Now only the vaccine-derived polio virus remains in Africa. What are vaccines and how do they work? Getty Images.

Vaccination 52

Vaccination Vaccine Contamination Development 52

Drug Discovery World

MAY 11, 2023

Gene-based therapeutics and vaccines hold immense potential for more efficient and personalised treatment and prevention of complex diseases. In these cases, injection of the viral vector vaccines induced the production of antibodies recognising platelet factor 4 (PF4) found on patients’ platelets 1.

Production 52

Production Gene Protein Vaccination 52

Delveinsight

AUGUST 12, 2020

While in the indirect method, transmission from contaminated water, food, or by Insect bites occur. Moreover, the studies of the emergence of these diseases, the vectors that spread them, and the vaccine development process take a huge amount of human and financial resources apart from the cost of lives.

Contamination 59

Contamination Vaccination Vaccine Bacteria 59

XTalks

MAY 20, 2022

Britain recently announced it will be offering the smallpox vaccine, which is 85 percent effective against monkeypox according to the World Health Organization (WHO) , to healthcare workers in the country due to the handfuls of cases being reported across Europe. Related: Malaria Vaccine a Breakthrough Success with 77 Percent Efficacy.

Vaccination 98

Vaccination Vaccine Contamination Licensing 98

Pharmaceutical Technology

MAY 17, 2023

One big challenge is contamination. It can cost millions of dollars to remove contamination from a manufacturing process and this causes a consequent delay to the preparation of the drug. As with contamination, variation in outcomes and product quality are often a result of the raw materials used.

Insulin 130

Insulin Production Manufacturing Contamination 130

Pharmaceutical Technology

DECEMBER 8, 2022

Another important example is digital twins, which are enabling the development and installation of new equipment and production processes with less risk and faster timelines. Quality levels from ten years ago are no longer acceptable at this moment – that’s regarding contamination and very small defects. By Datwyler. United Kingdom.

Manufacturing 246

Manufacturing Packaging Packaging Production 246

Roots Analysis

OCTOBER 16, 2023

Biopharmaceutical filtration is a critical step in the production of biopharmaceuticals, including proteins, antibodies, and vaccines. It involves the separation of unwanted particles from biological materials to obtain contaminant free products. Particle Removal: This is the primary function of these filtration systems.

Bacteria 40

Bacteria Production Contamination Protein 40

XTalks

MAY 29, 2024

In its acquisitions, J&J also acquired antibody-drug conjugate (ADC) developer Ambryx and cardiac med tech Laminar along with more than 50 smaller, early-stage licensing deals and partnerships. billion upfront buyout of GLP-1 drug developer Carmot Therapeutics. The vaccine earned $8.89 billion Swiss francs ($7.10

Pharma Companies 52

Pharma Companies Sales FDA Approval Vaccination 52

Roots Analysis

OCTOBER 24, 2023

The limitations of stainless-steel bioreactors such as high risk of contamination, process related challenges and high operational cost have prompted innovators to develop more advanced single use bioreactor in order to meet the rising demand for safe and efficacious biotherapeutics.

Manufacturing 40

Manufacturing Contamination Marketing Production 40

Advarra

MARCH 31, 2023

The use of engineered genetic materials in clinical trials is rapidly expanding, with potential applications for genetic vaccines, gene-modified cellular therapies, and gene therapies. For example, the Pfizer and Moderna mRNA COVID vaccines utilize lipid nanoparticles, while other approaches utilize genetically engineered viruses.

Engineer 52

Engineer Genetics Clinical Research Research 52

The Pharma Data

NOVEMBER 10, 2020

coli O157:H7 strain found by Michigan Department of Agriculture and Rural Development (MDARD) in Tanimura & Antle brand packaged single head romaine lettuce. 15 or 16 due to possible contamination with E. coli O157:H7 outbreaks that occurred in 2019 resulting in contamination of romaine lettuce in the Salinas Valley growing area.

Contamination 52

Contamination Packaging Packaging Production 52

Drug Discovery World

MARCH 21, 2023

The work promises to reduce the threats of viral contamination when harnessing bacteria to produce medicines such as insulin as well as other useful substances, such as biofuels. Currently, viruses that infect vats of bacteria can halt production, compromise drug safety, and cost millions of dollars. “We

Engineer 52

Engineer Genetic Engineering Scientist Bacteria 52

The Pharma Data

JANUARY 6, 2021

Two boys, a 23-month-old and a 6-year-old, developed lung cancers that proved an exact genetic match to cervical cancers within their mothers at the time of birth, Japanese researchers report. Most cervical cancers are caused by human papillomavirus (HPV), a virus against which there is an effective vaccine. WEDNESDAY, Jan.

Vaccination 52

Vaccination Vaccine Doctors Doctor 52

Drug Discovery World

FEBRUARY 8, 2023

As such, characterising the proportions of empty, partially-filled, and full AAV capsids is vital for determining sample quality and estimating efficacy during both process development and for quality control. What makes an ideal AAV analytics tool for process development? Figure 2: A typical mass photometry measurement of AAV capsids.

Gene Therapy 52

Gene Therapy Gene Antibody Production 52

pharmaphorum

SEPTEMBER 9, 2022

Rising global temperatures will, for example, enhance the spread of mosquito-borne diseases like malaria and Zika, increasing the need for effective vaccines. Water-borne illnesses are also likely to become more common, as increased rain and storm surges contribute to flooding and contaminated run off.

Production 90

Production Pharma Companies Generic Drugs Contamination 90

XTalks

OCTOBER 16, 2020

The drug was developed by biotech company Regeneron Pharmaceuticals, Inc. Related: First Ebola Vaccine Cleared by European Commission. “We Inmazeb was developed through Regeneron’s proprietary ‘rapid response’ VelocImmune technology and associated VelociSuite technologies for producing fully human monoclonal antibodies.

Antibody 98

Antibody Drugs Clinical Trials Clinical Trials 98

The Pharma Data

OCTOBER 30, 2020

In particular, the Committee appreciated WHO’s critical role in developing evidence-based guidance and recommendations; providing countries with technical assistance and operational support; communicating clear information and addressing misinformation; and convening the Solidarity Trials and the Access to COVID-19 Tools (ACT) Accelerator.

Regulation 52

Regulation Vaccination Vaccine Compliance 52

XTalks

SEPTEMBER 14, 2020

“Vaccine Nationalism” Could Prove the Undoing of COVID-19 Containment. Tension is mounting as nations big and small jockey around industry to ensure they are first in line to access a vaccine, should one prove to be successful against COVID-19. Moderna’s COVID-19 Vaccine. The price of that prize is incalculable.

Vaccination 92

Vaccination Vaccine Antibody Life Science 92

Roots Analysis

FEBRUARY 1, 2024

Cold chain is a three-fold concept, involving certain aspects that can be co-related to science, technology, and process development. In the absence of suitable temperature controlled packaging solutions, the products packaged, such as vaccines, biologics, cell and gene therapies might get exposed to extreme ambient temperatures.

Packaging 40

Packaging Packaging Containment Production 40