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Uncovering packaging impurities with rAAV genome sequencing

Drug Discovery World

Join DDW for this exclusive free event, ‘ rAAV genome sequencing with Oxford Nanopore uncovers transgene integrity and packaging impurities ’. The post Uncovering packaging impurities with rAAV genome sequencing appeared first on Drug Discovery World (DDW). The event will be supported by Oxford Nanopore Technologies.

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rAAV Genome sequencing uncovers transgene integrity and packaging impurities

Drug Discovery World

Attendees will hear how library preparation, assessed data quality, and generated important rAAV metrics such as integrity of DNA cargo, truncation events, chimeric transgenes, and levels of co-packaged impurities were performed. A live Q&A session follows the webinar presentation.

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How rAAV genome sequencing uncovers transgene integrity

Drug Discovery World

Join DDW for this exclusive free event, ‘ rAAV genome sequencing with Oxford Nanopore uncovers transgene integrity and packaging impurities ’. The post How rAAV genome sequencing uncovers transgene integrity appeared first on Drug Discovery World (DDW). The event will be supported by Oxford Nanopore Technologies.

Genome 52
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DDW event focusses on rAAVs and long-read nanopore sequencing

Drug Discovery World

Join DDW for this exclusive free event, ‘ rAAV genome sequencing with Oxford Nanopore uncovers transgene integrity and packaging impurities ’. The event will be supported by Oxford Nanopore Technologies. The event will take place on 13 May, 4PM BST.

DNA 98
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How can long-read nanopore sequencing support gene therapy delivery?

Drug Discovery World

Join DDW for this exclusive free event, ‘ rAAV genome sequencing with Oxford Nanopore uncovers transgene integrity and packaging impurities ’. The event will be supported by Oxford Nanopore Technologies. The event will take place on 13 May, 4PM BST.

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Modernizing cell culture processes for the next wave of genomic medicine

Pharmaceutical Technology

The field of genomic medicine has reached a true turning point. More efficient, suspension-based cell culture processes are urgently needed in the now fast-developing genomic medicine space. Two-Plasmid Packaging System for Recombinant Adeno-Associated Virus. CEVEC became part of Cytiva in October 2022. link] [2] Tang Q, et al.

Genome 244
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Guide to using AAV vectors in gene therapy

Drug Discovery World

The event aimed to help the audience understand the AAV workflow, from upstream methods for AAV production and validation to downstream analysis of the packaged product for enhanced therapeutic development. Questions were fielded from the audience, which included: What analysis will be performed to evaluate host or other DNA contamination?