Scienmag

JUNE 25, 2021

A new study by UC Davis researchers confirms the low likelihood that SARS-CoV-2 contamination on hospital surfaces is infectious. The study, published June 24 in PLOS ONE, is the original report on recovering near-complete SARS-CoV-2 genome sequences directly from surface swabs.

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Contamination Genome Genomics Research 41

Pharmaceutical Technology

APRIL 27, 2023

Genomic medicine development was ranked as the top industry trend for 2023 in a survey of 198 GlobalData Pharma clients and prospects conducted between October and November 2022. Every stage of development should result in a reproducible, safe drug product with no cross contamination from one batch to another. billion by 2028.

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Manufacturing RNA Contamination Vaccination 130

Drug Discovery World

FEBRUARY 8, 2024

These include automated solutions, proprietary genomics protocols, specialists to advise on global cGMP repository and logistics, plus experts to guide researchers through advanced therapy development. Questions were fielded from the audience, which included: What analysis will be performed to evaluate host or other DNA contamination?

Gene Therapy 59

Gene Therapy Gene Bioinformatics Life Science 59

Drug Discovery World

OCTOBER 3, 2023

These include automated solutions, proprietary genomics protocols, specialists to advise on global cGMP repository and logistics, plus experts to guide researchers through advanced therapy development. Questions were fielded from the audience, which included: What analysis will be performed to evaluate host or other DNA contamination?

Gene Therapy 52

Gene Therapy Gene Life Science Bioinformatics 52

XTalks

MARCH 10, 2022

As the leader in genomic sequencing, Clear Labs helps its clients better understand and manage pathogens, from foodborne illnesses to SARS-CoV2. This new era of NGS-empowered software tools offers a more accurate and deeper understanding of microbial contamination, helping drive root cause analysis and source eradication.

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Manufacturing Genome Genomics Contamination 98

XTalks

JANUARY 18, 2021

coli contamination. Since lettuce requires plenty of irrigation water during cultivation, cross-contamination often causes an E. However, a positive takeaway from the presentation was the potential of whole genome sequencing (WGS) in helping detect outbreaks. coli outbreak. For example, in three years, there have been nine E.

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Contamination Regulation Cosmetics Genome 52

Drug Discovery World

AUGUST 10, 2022

If the gene does not integrate into the genome, the cell will not become a CAR T cell. Furthermore, even if the transgene enters the cell in the correct numbers, the location where the gene integrates into the genome is somewhat random. The gene could also bury itself in a silenced region of the genome, leaving the gene dormant.

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Manufacturing Gene Genome Genomics 98

Drug Discovery World

APRIL 25, 2024

Automation has emerged as a tool which teams now use to free-up the time scientists spend doing manual tasks for cell lines and also to ensure the consistency of cell cultures and reduce the chances of contamination 2.

Development 59

Development Protein In-Vivo Life Science 59

Drug Discovery World

FEBRUARY 28, 2023

Finally, dosing and timing may be controlled simply by adjusting the amount of mRNA delivered to the cells, rather than relying on inducible systems that are integrated into the genome. The identity of the transcript is confirmed by Sanger sequencing.

Genetics 52

Genetics Genetic Analysis Vaccination Vaccine 52

Drug Discovery World

FEBRUARY 8, 2023

During AAV process development, there are numerous variables that need to be optimised to maximise the number of full capsids while minimising contaminants. Robustness: to be able to tolerate matrix effects (type of buffer, residual contaminants, ionic strength, etc.) What makes an ideal AAV analytics tool for process development?

Gene Therapy 52

Gene Therapy Gene Antibody Production 52

XTalks

NOVEMBER 7, 2022

These tumor-derived entities are used to derive genomic and proteomic data. However, Dr. Bahassi reported that the selection of CTCs using this method is often not very efficient and the CTC population is usually highly contaminated with leukocytes. Detection of Genomic Alterations from cfDNA: Targeted, Non-Personalized Approaches.

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Drug Discovery World

MAY 11, 2023

In addition, there are other sources of protein contamination, such as from cell culture medium supplements — for example, bovine serum albumin.” coli, and Pichia cells. These host cells alone contain over a thousand HCPs.

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Production Gene Protein Vaccination 52

pharmaphorum

MARCH 8, 2022

DI: Oncology is a hugely exciting area at the moment, particularly the further focus on genome testing to help identify specific mutations in the DNA and select the best treatment option for the patient and their type of cancer. Darina Shopova is design engineer at Envair Technology, working on the design and development of rigid isolators.

Life Science 98

Life Science Engineer Scientist Doctors 98

XTalks

FEBRUARY 26, 2021

It wasn’t until the early 1970s when large numbers of other cell lines were found to be contaminated with HeLa in some labs that an investigation was launched. However, when a strain of HeLa cells was sequenced and researchers published its genome in 2013, Skloot informed the Lacks family about this.

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Scientist Research Genetics Cosmetics 69

The Pharma Data

NOVEMBER 15, 2020

She currently serves as a non-executive director on the board of Genfit, S.A.,

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Clinical Trials Clinical Trials Production Trials 40