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Sanofi and GSK COVID-19 vaccine candidate demonstrates strong immune responses across all adult age groups in Phase 2 trial

The Pharma Data

Adjuvanted recombinant COVID-19 vaccine candidate triggered strong neutralizing antibody responses in all adult age groups. High immune response after a single dose in patients with prior infection shows strong booster potential. For media and investors only. Issued: London UK. About the Phase 2 study.

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Research Roundup: UK Strain of COVID-19 and More

The Pharma Data

Researchers say, however, they have never seen a virus acquire more than a dozen mutations at once. Of the 17 mutations, eight are in the gene that encodes the spike protein. One is N501Y, which has been previously shown to increase how the spike protein binds to the ACE2 receptor. In research in South Africa in B.1.1.7,

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INOVIO Announces Publication of Phase 1 Data from its COVID-19 DNA Vaccine Candidate, INO-4800 in The Lancet’s EClinicalMedicine

The Pharma Data

Cellular (T cell) response were observed to multiple regions of the spike protein including the RBD region. 74% had measurable cellular responses at the 1.0 mg dose group demonstrated cellular responses. The 1.0 mg and 2.0 mg dose group and 84% demonstrating neutralizing antibodies in the 2.0

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Evusheld long-acting antibody combination recommended for approval in the EU for the pre-exposure prophylaxis (prevention) of COVID-19

The Pharma Data

Discovered by Vanderbilt University Medical Center and licensed to AstraZeneca in June 2020, the human monoclonal antibodies bind to distinct sites on the SARS-CoV-2 spike protein(10) and were optimised by AstraZeneca with half-life extension and reduction of Fc effector function. W911QY-21-9-0001.

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Who are the AACR Scientific Achievement Award winners?

Drug Discovery World

The American Association for Cancer Research (AACR) will honour the following cancer researchers, physician-scientists, advocates, and journalists during its annual meeting to be held April 14-19 at the Orange County Convention Center in Orlando, Florida. June’s award lecture will be held on Sunday April 16 at 4:30pm ET.

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AZD7442 PROVENT Phase III prophylaxis trial met primary endpoint in.

The Pharma Data

More than 75% of participants had co-morbidities, which include conditions that have been reported to cause a reduced immune response to vaccination. Genetic and structural basis for recognition of SARS-CoV-2 spike protein by a two-antibody cocktail. W911QY-21-9-0001. Increased resistance of SARS-CoV-2 variant P.1 Dong J, et al.

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COVID-19 Pandemic Coverage

XTalks

The company’s candidate vaccine, mRNA-1273, is a synthetic messenger RNA that encodes the stabilized SARS-CoV-2 spike protein. The University of Oxford/AstraZeneca partnership, in turn, is testing a viral-vectored coronavirus vaccine that again expresses the spike protein of SARS-CoV-2 virus. Drugs and Vaccines.