Understanding the Crohn’s disease patient [whitepaper]

At Antidote, we understand that successfully engaging patients for a clinical trial starts with a deep understanding of the patient population. Knowing who patients are, what motivates them, and what messages will resonate with them can all be beneficial when finding individuals who may be eligible to take part in specific studies.

We recently analyzed a data set of nearly 1,000 Crohn’s patients to determine how best to reach these individuals with clinical trial opportunities. Crohn’s disease, a type of inflammatory bowel disease, is estimated to impact three million Americans. The symptoms can include abdominal cramps, diarrhea, and constipation, in addition to complications with weight loss and fatigue. Currently, there is no cure for Crohn’s disease, and treatment instead revolves around symptom management — but with certain medications, foods, drinks, and stress all being triggers, flare-ups can often feel unpredictable.

The data we collect as patients search for trials offers us insight into which patients may be eligible for particular trials, but critically, it allows us to understand the motivational factors that drive patients to participate in research — and to plan out our recruitment accordingly. The data we collected includes:

  • Insights on flare-ups, resections, and medication history — all with regard to age and time since diagnosis. 
  • A comparison of the number of medications a patient is on to the types of medications they are on to understand patterns of medication use. 
  • A discovery that 66% of patients on Crohn’s patients experience inadequate relief or intolerable side effects from their medications, and an analysis of the number of and types of medications those patients were on. 

To get the details on these insights and learn more about our work, get the whitepaper today.