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AstraZeneca makes a big RNA play, teaming up with VaxEquity

pharmaphorum

Development of the shot eventually fell behind mRNA rivals from BioNTech and Moderna, and Imperial eventually pivoted its efforts to development of possible boosters directed at emerging variants based on its self-assembling RNA (saRNA) platform. billion takeover of Translate Bio and $470 million acquisition of Tidal Therapeutics.

RNA 52
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Myocarditis case mars Sarepta DMD gene therapy readout

pharmaphorum

The headline readout was from Cohort 1 of its ENDEAVOR trial – in 20 subjects aged four to seven – which showed a significant improvement compared to controls at one year on the North Star Ambulatory Assessment (NSAA) scale compared to a matched control group.

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What HCPs think about blood clots linked to COVID-19 vaccines

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This sudden increase is due to reports of rare blood clots in recipients of the COVID-19 vaccines developed by AstraZeneca and more recently Johnson & Johnson. risk of developing blood clots with the contraceptive pill, with the ~0.0003% risk of blood clots with the AstraZeneca vaccine. Author Bio. HCPs compared the ~0.1%

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The challenges and trends of cell & gene therapies 

Drug Discovery World

DDW Editor Reece Armstrong looks at the cell and gene therapy landscape, examining the challenges facing developers and the trends we can expect to see throughout the year. . Among these include Zolgensma, Novartis’ gene therapy drug for spinal muscular atrophy (SMA), which made headlines in the UK for its £1.79

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DDW readers’ top drug discovery developments of 2023

Drug Discovery World

Neuroscience was also a key area for the year for the audience, with a number of ground-breaking developments, including a new potential treatment for schizophrenia and positive results for psychedelics as an antidepressant. Variant of the month, EG.5 5 or ‘Eris’ was found in more than 50 countries.

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CAR-T Beyond Oncology Digital Summit

pharmaphorum

The 3 rd CAR-T approval recently hit the headlines for Kite Pharma in mantle cell lymphoma. Due to this clear clinical and commercial success, the oncology field has become saturated with companies with the hope to develop a cure… but are you aware of the new CAR-T movement beyond oncology?

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Mega biotech Centessa beams up ex-Warp Speed science chief Slaoui

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But it’s the appointment of Slaoui as chief scientific advisor that’s attracting headlines, with an R&D approach that looks to be inspired by his time in charge of research at GlaxoSmithKline. Centessa has a similar approach, with each biotech working almost autonomously on a project already validated and ready for further development.