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Positive Phase I results for KMO inhibitor in inflammatory disorders

Drug Discovery World

Kynos Therapeutics Founder and CSO Damian Mole said: “The headline data from this Phase I study have demonstrated KNS366 is safe and well tolerated at exposures that resulted in a high level of KMO enzyme inhibition.

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Astellas taps GO’s glycoprotein platform with $783.5m deal

pharmaphorum

For Astellas, GO will discover high-affinity antibodies against the O-glycoprotein targets, with the Japanese drugmaker responsible for subsequent research activities, clinical development and commercialisation if they reach the market. The post Astellas taps GO’s glycoprotein platform with $783.5m deal appeared first on.

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This week in drug discovery (6-10 February)

Drug Discovery World

Clinical drug trials have made the headlines this week, as it was revealed that breast cancer still tops the bill for number of clinical studies and the shortcomings in current methods to ensure representation of patient populations in trials were exposed.

Drugs 52
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Ozempic® 2.0 mg approved in the US for the treatment of type 2 diabetes

The Pharma Data

About the SUSTAIN clinical programme The SUSTAIN clinical development programme for once-weekly subcutaneous semaglutide injection currently comprises 11 phase 3 global clinical trials, including a cardiovascular outcomes trial, involving more than 11,000 adults with type 2 diabetes.

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Blue Oak taps AI specialist Exscientia for CNS drug discovery

pharmaphorum

The UK company made headlines earlier this year when partner Sumitomo Pharma started clinical trials of a drug candidate for obsessive compulsive disorder, said to be the first medicine developed using AI to enter testing in humans.

Drugs 58
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Once-weekly insulin icodec demonstrates superior reduction in HbA1c vs insulin degludec in people with type 2 diabetes in ONWARDS 2 phase 3a trial

The Pharma Data

Novo Nordisk today announced headline results from the ONWARDS 2 trial, a phase 3a, 26-week efficacy and safety treat-to-target trial investigating once-weekly insulin icodec vs insulin degludec in 526 people with type 2 diabetes switching from daily insulin.

Insulin 52
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4 Life Science Trends To Pay Attention To in 2021

XTalks

With COVID-19 having dominated the headlines in 2020, the coronavirus pandemic will inevitably continue to be the biggest story in 2021, but hopefully for more positive reasons. The burden of clinical trials is on all patient groups and patient segments. This includes how you engage with patients and how samples are collected.