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This week in drug discovery (20-24 March)

Drug Discovery World

This week we have seen a number of developments in the treatment of solid tumours hitting the headlines. Pennsylvania researchers may have found a way to boost CAR-T therapy in these tumours, previously only successful in blood cancers, which could have huge implications for cancer treatment.

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Astellas taps GO’s glycoprotein platform with $783.5m deal

pharmaphorum

For Astellas, GO will discover high-affinity antibodies against the O-glycoprotein targets, with the Japanese drugmaker responsible for subsequent research activities, clinical development and commercialisation if they reach the market.

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Merck cuts $1bn deal with Janux for cancer T-cell therapies

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Each programme includes undisclosed upfront and milestone payments plus royalties on sales, with Merck indicating in a statement that it will be funding the research. The headline of the deal was an experimental COVID-19 drug, but it also claimed rights to a pipeline of early-stage oncology drugs. Other recent deals include a $2.8

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Build Connections with B2B Audiences through the Xtalks Life Science Podcast

XTalks

This podcast offers a comprehensive view of noteworthy news stories that are making headlines in the pharma, biotech, healthcare and medical device sectors. Clinical Research: Stay updated on new and ongoing clinical trials for various drugs , treatments and medical devices, along with the latest trial data as it becomes available.

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The challenges and trends of cell & gene therapies 

Drug Discovery World

Among these include Zolgensma, Novartis’ gene therapy drug for spinal muscular atrophy (SMA), which made headlines in the UK for its £1.79 With the sector still in its infancy and with growing regulatory approvals and steady funding, it makes sense the researchers will be drawn to such an exciting and promising field of work.

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Why the New Xtalks Life Science Podcast is Essential Listening for Industry Professionals

XTalks

The weekly podcast will feature an overview of some of the key news stories making headlines, along with insight into the latest and evolving trends, innovations and landmark happenings in the pharma, biotech and medical device industries. She has presented her research at international conferences and published several peer-reviewed papers.

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DDW readers’ top drug discovery developments of 2023

Drug Discovery World

Representing a dominant field of drug discovery, it isn’t surprising that breakthroughs in cancer research were popular with DDW readers in 2023, particularly strategies to overcome treatment resistance and prevent the spread of disease. Of the trial participants, 53.3% responded and 20% are in remission (i.e. Variant of the month, EG.5