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Sitagliptin Promising Addition for Preventing Acute GVHD

The Pharma Data

7, 2020 — For patients undergoing myeloablative allogeneic hematopoietic stem cell transplantation, sitagliptin combined with tacrolimus and sirolimus results in a low incidence of grade II to IV acute graft-versus-host disease (GVHD) by day 100, according to a study published in the Jan. More News Resources. THURSDAY, Jan.

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Klinrisk Secures National Kidney Foundation’s Investment for Kidney Disease Care

XTalks

With an active role in research, the National Kidney Foundation strives to reach at-risk populations, as well as early-stage and late-stage patients, providing them with resources to manage the disease effectively. The Innovation Fund has also recently invested in Relavo and Medigo to further technological advancements in renal health.

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Disability Diversity in Clinical Trials Initiative Launched by BMS in Time for Disability Pride Month

XTalks

A study published in the Journal of the American Medical Association has analyzed 338 Phase III and Phase IV clinical trials and revealed that 12.4 percent of people with developmental or intellectual disabilities and 1.8

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Pfizer Acquires Amplyx Pharmaceuticals

The Pharma Data

Deal expands anti-infectives pipeline with addition of novel antifungal Phase 2 candidate, Fosmanogepix (APX001). With both IV and oral formulations in development, Fosmanogepix may allow for the transition from IV to oral, thus potentially enabling, for the benefit of patients, the continuation of treatment outside the hospital.

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JAPAN’S MHLW APPROVES PFIZER’S CIBINQO® (ABROCITINIB) FOR ADULTS AND ADOLESCENTS WITH MODERATE TO SEVERE ATOPIC DERMATITIS

The Pharma Data

The approval of CIBINQO in Japan was based on the results from 1,513 patients across four Phase 3 studies, ranging from 12 to 16 weeks of treatment, and a long-term extension study from a robust clinical trial program. iii,iv In Japan, AD affects approximately 3% of adults and 13% of children.

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CytomX Therapeutics Announces Pricing of $100 Million Public Offering of Common Stock – Jan 21, 2021

The Pharma Data

CytomX expects to use any remaining net proceeds from this offering for capital expenditures, working capital and other general corporate purposes.

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FDA Authorizes Phase 1 Trial of ImmunityBio’s Novel COVID-19 Vaccine Candidate hAd5; Dual Construct is Designed to Drive Both T Cell and Antibody Immunity

The Pharma Data

Food and Drug Administration (FDA) to begin a Phase I clinical trial of hAd5-COVID-19, the company’s novel COVID-19 vaccine candidate that targets both the inner nucleocapsid (N), engineered to activate T cells, and outer spike (S) protein, engineered to activate antibodies against the coronavirus (SARS-CoV-2). i,ii,iii,iv.