Rethinking Clinical Trials

OCTOBER 18, 2023

The World Health Organization defines social determinants of health as non-medical factors that influence health outcomes and conditions in which people are born, grow, work, live, and age, and the wider set of forces and systems shaping the conditions of daily life.

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Rethinking Clinical Trials

SEPTEMBER 30, 2022

To be eligible, patients needed to be first-time mothers aged 15 and older who met the income-eligibility criteria for Medicaid and were no more than 28-weeks gestation at enrollment. The primary outcome was a composite of at least one of small for gestational age, or low birth weight, or preterm birth or perinatal mortality.

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Rethinking Clinical Trials

AUGUST 22, 2022

Trial participants were adults ages 30-85, who tested positive for SARS-CoV-2 within 3 days, with fewer than 7 days of symptoms, no known prior infection with SARS-CoV-2, no severe kidney, liver, or heart failure. We also kept equal focus on follow-up. Learn more about COVID-OUT. pctGR, @Collaboratory1.

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Rethinking Clinical Trials

JANUARY 17, 2024

Tags #pctGR, @Collaboratory1 The post Grand Rounds January 12, 2024: Design and Implementation of a Weighted Lottery to Equitably Allocate Scarce Covid-19 Resources (Erin K. We know there is a digital gap in disadvantaged patients and elderly patients. Many patients did not answer the phone.

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pharmaphorum

NOVEMBER 19, 2021

It is recommended as a treatment for people aged two months and older with types 1, 2 and 3 SMA, as well as some people with the condition before they start showing symptoms. million price tag make it is the most expensive treatment ever approved for NHS funding.

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World of DTC Marketing

SEPTEMBER 9, 2021

A study put a price tag on American’s bad eating habits: $50 billion a year in health care costs, attributable to cardiometabolic diseases such as heart disease, stroke, and type 2 diabetes. However, experiences among individual hospitals vary, and about one-quarter of both for-profit and not-for-profit hospitals lost money in 2016.

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pharmaphorum

JUNE 12, 2022

Beti-cel has already been approved for marketing in Europe as Zynteglo, with a price tag of around $1.8 Haematopoietic stem cell transplantation (HSCT) offers a chance of a cure, but is only possible when a donor with a matching human leukocyte antigen (HLA) signature, within the correct age range, is available.

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Rethinking Clinical Trials

JULY 14, 2023

Tyson School of Medicine Slides Keywords Pragmatic Clinical Trial, GGC4H, Prevention Key Points Guiding Good Choices for Health Study (GGC4H) is about the Guiding Good Choices (GGC) intervention, a group-based program for parents and caregivers of younger adolescents (ages 9-14).

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pharmaphorum

APRIL 14, 2022

million price tag. Patients with the most severe form of inherited disorder develop life-threatening anaemia from the age of around four to six months and have to undergo monthly blood transfusions as well as additional treatment to prevent complications, such as chelation drugs to remove excess iron from the body.

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Drug Discovery World

OCTOBER 31, 2023

In the combined Phase I and II clinical trial, five children under one year of age with the condition also known as mucopolysaccharidosis type II (MPS II) will be treated with autologous hematopoietic stem cell (HSC) gene therapy.

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Rethinking Clinical Trials

NOVEMBER 21, 2022

There were pragmatic inclusion criteria of being admitted to PICU/HDU, age 36 weeks and older and less than 16 years, and assessed by the treating clinician to require noninvasive respiratory support either for an acute illness or within 72 hours of extubation following a period of invasive ventilation. pctGR, @Collaboratory1.

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XTalks

JUNE 8, 2021

SMA is a rare genetic condition that leads to a loss of motor neurons that results in progressive muscle weakness and wasting, paralysis and, when left untreated in its most severe form, breathing difficulties leading to permanent ventilation or death for most patients by the age of two. With a price tag of over $2.5

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The Pharma Data

JANUARY 31, 2021

Utilizing Clover’s proprietary Trimer-Tag© technology, S-Trimer is a trimeric SARS-CoV-2 spike (S)-protein subunit vaccine candidate. About Trimer-Tag© Technology. Trimer-Tag© is an innovative drug development platform which allows the production of novel, covalently-trimerized fusion proteins. —- End —-.

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Rethinking Clinical Trials

DECEMBER 6, 2022

The trial enrolled 187 patients, with 35% women, 47% African American, 10% Hispanic, age 59 years. There were two exploratory endpoints: change in mean daily step counts from baseline to 6 months and change in metabolomic profiling from baseline to 3 months. Enrollment halted before planned sample size of 200 due to COVID-19.

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pharmaphorum

NOVEMBER 19, 2020

Lucentis (ranibizumab) was first FDA approved in 2006 for wet age-related macular degeneration (wet AMD) and has picked up approvals in related eye conditions ever since, although its patent expired in June.

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XTalks

DECEMBER 13, 2023

Both gene therapies are approved for individuals 12 years of age and older with sickle cell disease. The landmark approvals were awarded to bluebird bio’s Lyfgenia (lovo-cel) and Vertex Pharmaceuticals and CRISPR Therapeutics’ jointly developed Casgevy (exa-cel). Casgevy is also the first ever CRISPR/Cas9-based therapy approved in the US.

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The Pharma Data

MARCH 16, 2022

using SNAP-tag) involves labeling cell proteins with a fluorescent dye, thereby enabling researchers to observe how proteins interact in the living cell and where in the cell they are located. With Spirochrome, he commercialized fluorescent probes for cell biology, while with Covalys, he marketed SNAP-tag and other protein labeling methods.

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The Pharma Data

DECEMBER 3, 2020

Utilizing Clover’s proprietary Trimer-Tag © technology, S-Trimer is a trimeric SARS-CoV-2 spike (S)-protein subunit vaccine candidate. About Trimer-Tag © Technology. Trimer-Tag © is an innovative drug development platform which allows the production of novel, covalently-trimerized fusion proteins.

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The Pharma Data

MARCH 7, 2022

The approach will allow researchers to understand the role individual genes play in normal cell growth and development, in aging, and in such diseases as cancer, said Shiri Levy, a postdoctoral fellow in UW Institute for Stem Cell and Regenerative Medicine (ISCRM) and the lead author of the paper. Cas9 binds and uses RNA as an address-tag.

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pharmaphorum

SEPTEMBER 15, 2020

“Digitally native brands are typically agile businesses from the ground up, and agility and flexibility are part of their core makeup,” says Joe Holmes, vice president, marketing services, US at Tag. Jeremy Richter, Tag. Joe began his life at Tag in the UK, bringing efficiencies to his clients, working across all conceivable channels.

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The Pharma Data

JANUARY 31, 2021

Utilizing Clover’s proprietary Trimer-Tag© technology, S-Trimer is a trimeric SARS-CoV-2 spike (S)-protein subunit vaccine candidate. About Trimer-Tag© Technology. Trimer-Tag© is an innovative drug development platform which allows the production of novel, covalently-trimerized fusion proteins.

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Rethinking Clinical Trials

SEPTEMBER 22, 2022

The DANFLU-1 trial is a large-scale pragmatic RCT that looked at high-dose vs standard-dose flu vaccine to test whether high-dose vaccines might reduce hospitalizations among the elderly, age 65 and older. 34,000 study invitations were sent out and 12,551 participants consented and were randomized in the study. Learn more.

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Rethinking Clinical Trials

SEPTEMBER 21, 2023

The sample included 2,744 adults at least 18 years of age who currently or had previously received SNAP benefits. I’m proposing to evaluate another incentive program with that in mind in order to more closely track those purchase.

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pharmaphorum

JANUARY 21, 2022

Balancing the incentivisation of innovation against affordable access to revolutionary new medicines is an age-old conundrum in the biopharmaceutical industry. In recent years, revolutionary medicines have come with price tags to match, but this is simply a symptom of our current model.

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pharmaphorum

JUNE 2, 2021

It added that there is evidence that Evrysdi is a life-extending treatment for SMA type 1, the most serious from of the disease that generally leads to death before the age of 2 if untreated, and as an oral drug is an alternative for people who cannot have the other SMA treatment options.

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The Pharma Data

OCTOBER 21, 2020

The patients in this study were newly diagnosed with Ph-positive ALL and ranged in age from 24 to 82. When it came to market in 2014, the price tag for one treatment cycle was $89,000. It is already approved in the United States for certain ALL patients. The chemo-free approach could shorten that.

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The Pharma Data

OCTOBER 21, 2020

The patients in this study were newly diagnosed with Ph-positive ALL and ranged in age from 24 to 82. When it came to market in 2014, the price tag for one treatment cycle was $89,000. It is already approved in the United States for certain ALL patients. The chemo-free approach could shorten that.

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Druggist

OCTOBER 25, 2020

Virasoothe Cooling Gel can be used in toddlers and children from 6 months of age. Despite its higher price tag as compared with other products sold for the management of chickenpox PoxClin Cool Mousse is regarded as ‘highly-rated’ and well-priced product on Amazon.co.uk Buy on Amazon Price incl. Buy on Amazon Price incl.

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Delveinsight

FEBRUARY 25, 2021

A study published in Cancer Epidemiology, Biomarkers & Prevention last year, December, estimated that the annual use of Galleri, among other multi-cancer early detection blood tests, could decrease late-stage cancer diagnoses by more than 50% in people aged 50 to 79 in the U.S.

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pharmaphorum

AUGUST 28, 2020

But the advent of COVID-19 is proving to be something of a coming of age for digital epidemiology, which has been putting data from disparate sources to global use for the last 15 years. We are ingesting hundreds of thousands of pieces of information daily and we tag that information across locations, disease types, species, and case counts.

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The Pharma Data

OCTOBER 19, 2020

Share the video on your favourite social media channel, with the hashtag #WeAreFamily #COVID19 #HealthforAll and tag @WHO, @The_WorldWeWant and @thewhof. Upload your video to [link]. If you want your video to be considered for inclusion in the global We Are Family video, you will need to share your video by Monday, 30 November 2020.

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The Pharma Data

NOVEMBER 9, 2020

WeAreFamily #COVID19 #HealthforAll and tag @WHO, @The_WorldWeWant and @thewhof. Video clips will be selected based on age, geographical diversity, and appropriate physical distancing if the video includes groups of people beyond immediate family members and correct handwashing if singing along to the song while washing hands.

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Delveinsight

JULY 22, 2020

The hospital inventory is equipped with tagged sensors. Growing Aging population. Growing Old-age population in the coming years is likely to rely more on IoT based products as these products help measure even the minute variations in body vitals. Medical Equipment Tracking.

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FDA Law Blog

JUNE 27, 2023

The honor was bestowed on only 183 attorneys, which is awarded to “top attorneys under 40 whose legal accomplishments belie their age.” In addition to Mr. Karst, ten other HP&M Directors were tagged as “Recommended” by WWL: Life Sciences 2023: Ricardo Carvajal Robert A. Valentine , as a 2023 Rising Star. Dormer Jeffrey N.

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Rethinking Clinical Trials

FEBRUARY 22, 2023

The Heartline Trial is a randomized trial of up to 28,000 patients to test whether the new Apple watch (with built-in single lead EKG) can detect new onset atrial fibrillation in participants age 65 and older. Patients were enrolled via an app in this virtual trial. The consent form is electronic and approved by a central IRB.

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XTalks

SEPTEMBER 27, 2022

It is specifically indicated to slow the progression of neurologic dysfunction in boys four to 17 years of age with early, active CALD. The record-breaking price tag of Skysona is not surprising for one-time gene therapies like it. Symptoms of CALD typically appear in childhood (median age seven). Related: Bluebird’s $2.8M

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XTalks

FEBRUARY 27, 2024

Skyclarys (omobaloxone) was approved in 2023 for the treatment of adults and pediatric patients 16 years of age and older with Friedreich’s ataxia, a rare, neurological disease​​. Sarepta hopes to clarify Elvidys’ effectiveness in older children in a confirmatory trial.

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