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Cannabinoids receptors: popular preclinical target but banned in 137 countries

Pharmaceutical Technology

Despite this, the medical use of cannabinoid drugs is heavily restricted, including being banned in 137 countries, according to the United Nations. Collectively, cannabinoid receptors (CB1 and CB2) are currently the most popular targets in preclinical stage of development, with 391 drugs tagged in total.

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Risk-sharing agreements are growing at a rate of 24%

Pharmaceutical Technology

This is not the first treatment to come with a high price tag. 79% of risk-sharing agreements are finance-based According to GlobalData’s risk-sharing database, over 1,000 RSAs were made in the last decade across 28 countries and roughly 100 companies.

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Orphan drugs and where to launch them: The keys to Europe’s forgotten territories

Pharmaceutical Technology

Such movements have enabled pharmaceutical companies to increase their focus on rare diseases, and the number of orphan drug launches is steadily increasing. These countries will have a smaller patient pool due to population size and will likely carry a price tag that is significantly below that of higher GDP countries.”.

Drugs 147
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Grand Rounds October 20, 2023: A National Initiative to Eliminate Hepatitis C in the United States – Why This Matters to Clinical Trialists (Rachael L. Fleurence, PhD, MSc; Joshua M. Sharfstein, MD)

Rethinking Clinical Trials

Pilots for elimination programs for Hepatitis C have been successful in individual states and other countries. We spent 15 months working with the White House to get the program in the president’s budget and now our focus is on the Hill. Even when diagnosed, only 1 in 3 adults are cured of Hepatitis C in the U.S.

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Anti-Counterfeiting Technologies in Healthcare

Roots Analysis

Examples of such technologies include DNA Taggants (a unique DNA tag used in the product / packaging that can be scanned using a designated instrument / equipment), invisible printing technologies, digital watermark technologies and hidden markers / print technologies.

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Grand Rounds August 12, 2022: Equitably Including Diverse Participants in Pragmatic Clinical Trials (Consuelo H. Wilkins, MD, MSCI)

Rethinking Clinical Trials

Researchers push the focus on the population, but do we have the level of cultural humility required, and are we trustworthy enough to be doing this type of research and engaging these populations? These terms and designations were intended to restrict rights. The racism built into these categories does not go away when we do research.

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Oslo Medicines Initiative asks how to balance innovation incentivisation with security of access

pharmaphorum

Access to medicines is “one of the most challenging policy areas in every country in the European region” – it’s time to develop a solution that works for everyone. The outputs of the innovation process are proving prohibitively expensive for high-income countries, and way beyond the reach of low- and middle-income countries.”.