tag dna-methylation 
Scienmag
JULY 1, 2022
One way cells can control the activities of their genes is by adding small chemical modifications to the DNA that determine which genes are turned on or off. Methyl groups are one of these chemical modifications or tags.
The Pharma Data
MARCH 7, 2022
The new technique controls gene activity without altering the DNA sequence of the genome by targeting chemical modifications that help package genes in our chromosomes and regulate their activity. These methyl groups must be refreshed so if PRC2 is blocked the genes it has silenced. Cas9 binds and uses RNA as an address-tag.
Delveinsight
DECEMBER 3, 2020
It has been speculated that modifications to the epigenome drive cell ageing, especially a process known as DNA methylation, by which methyl groups are tagged onto DNA. Shinya Yamanaka discovered that the factors could alter the epigenome, and in that way modify mature cells back to a stem cell-like state.
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