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Grand Rounds October 7, 2022: Impact Of Handovers Of Anesthesia Care On Morbidity And Mortality (Melanie Meersch-Dini, MD)

Rethinking Clinical Trials

University Hospital Münster, Germany. In Germany, there are two levels of anesthesia, in-room anesthesiologists who are either trainees or a medical specialist (non-management). ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?. Speakers. Melanie Meersch-Dini, MD. Department of Anesthesiology, Intensive Care and Pain Medicine. Key Points.

Trials 130
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Orphan drugs and where to launch them: The keys to Europe’s forgotten territories

Pharmaceutical Technology

Due to the high price tags associated with these speciality medicines, innovators have naturally favoured big markets with high GDP such as the US and EU-5 (Germany, France, Spain, Italy, and the UK). The choice of where to launch an orphan drug is an important and difficult decision. Europe’s forgotten territories.

Drugs 147
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A broad range of unmet needs remains in the immuno-oncology space

Pharmaceutical Technology

High-prescribing physicians surveyed by GlobalData across eight major markets (8MM: US, France, Germany, Italy, Spain, UK, Japan, and China) identified a broad range of unmet needs in the IO space (see Figure 1). Despite the significant advances that have been made in the IO field, a huge level of unmet need remains.

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Drug Combo May Be Safe, Effective Therapy for Rare Leukemia

The Pharma Data

Among adults with ALL, 10% to 20% die during chemo, according to Dr. Dieter Hoelzer, of the University of Frankfurt, in Germany. When it came to market in 2014, the price tag for one treatment cycle was $89,000. But even with TKIs available, patients with Ph-positive ALL still undergo intensive chemotherapy — and it takes a toll.

Drugs 52
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Sprycel Plus Blincyto Drug Combo May Be Safe, Effective Therapy for Rare Leukemia

The Pharma Data

Among adults with ALL, 10% to 20% die during chemo, according to Dr. Dieter Hoelzer, of the University of Frankfurt, in Germany. When it came to market in 2014, the price tag for one treatment cycle was $89,000. But even with TKIs available, patients with Ph-positive ALL still undergo intensive chemotherapy — and it takes a toll.

Drugs 52
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Merck KGaA raises full-year forecast; Perlmutter’s new gig tackles ‘undruggable targets’

The Pharma Data

WHO to open a global pandemic ‘intelligence’ hub in Germany ( CNBC ). AbbVie’s Humira regains top pharma TV spender spot, while sibling brands Rinvoq and Skyrizi tag along ( Fierce ). . India approves Roche/Regeneron antibody cocktail to treat COVID-19 ( Reuters ). Medtech.

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Roctavian okay sets up another gene therapy test for Europe

pharmaphorum

million for the one-shot therapy – in other words, after any discounts that it may offer or outcomes-based agreements – aiming to launch first in Germany followed by France. BioMarin has said Roctavian will be available at a ‘net’ price of around €1.5 million spread over five years. million spread over five years.