Remove tag haematology
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A broad range of unmet needs remains in the immuno-oncology space

Pharmaceutical Technology

In contrast to ICIs, which are utilised against solid tumours, cell therapies and bispecifics have been transformational in the haematological cancer settings, with approvals across a range of leukaemias and lymphomas. Cost-related unmet needs also scored highly.

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Bristol Myers Squibb pays $475 million for exclusive rights to Dragonfly Therapeutics' IL-12 immunotherapy programme

The Pharma Data

The investigational therapy has obviously caught the eye of BMS, and it was confirmed that the company intends to exercise its newly bought rights to push the drug forward in oncology and haematology.

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After a slow start for expensive CAR-T therapies, drug developers revisit oral therapies for blood cancer

pharmaphorum

price tag of $475,000 when it was first launched in 2017 – and it becomes apparent that these may not be desirable treatment options for every patient and in every setting. Add to this the considerable cost of these medications – the first approved CAR-T, Novartis’ Kymriah (tisagenlecleucel), had a U.S. Professional reception of the findings.

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Meet the Researcher: Andreas Bader, Triumvira Immunologics

Drug Discovery World

For example, CAR Ts have accomplished awesome successes in haematologic malignancies, and people are also trying to apply these technologies to solid tumours – but successes remain pending. We have now our lead product in a Phase I/II study, which is a HER-2 directed tag T cell product for patients with HER-2 positive solid tumours.

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How data is crucial to the relaunch of the Cancer Moonshot

pharmaphorum

The Biobank was launched in 2020, with an initial aim of enrolling at least 1,000 patients with locally advanced or metastatic solid tumours and haematologic malignancies undergoing standard of care therapy. Building a bank. The entire process takes place in the physician’s office, alongside a clinician.