Remove tag heart-disease
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Grand Rounds February 3, 2023: Pragmatic Trials For Children With Congenital Heart Disease – Insights From The NITRIC Trial (Luregn Schlapbach, PhD, FCICM)

Rethinking Clinical Trials

All infants and children less than 2 years of age undergoing open heart surgery on cardiopulmonary bypass were eligible for the study with exclusions for diseases that implied high severity pre-bypass. The intervention was applied by perfusionists at a steady concentration from the start until the end of bypass.

Trials 130
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American health is in for a “world of hurt”

World of DTC Marketing

Cardiovascular disease deaths in the US have increased by nearly 17% since 2010, and are among the reasons that life expectancy in the U.S. The Global Burden of Disease study estimates that high sodium intake causes between 1 million and 5 million deaths per year globally” Then there is the obesity epidemic.

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Grand Rounds December 15, 2023: Diversifying Clinical Trials: A Path Forward (Roxana Mehran, MD, FACC, FAHA, MSCAI, FESC)

Rethinking Clinical Trials

Globally cardiovascular disease (CVD) prevalence had decreased between 1990 and 2010, but it has slightly increased since 2010. Tags #pctGR, @Collaboratory1 The post Grand Rounds December 15, 2023: Diversifying Clinical Trials: A Path Forward (Roxana Mehran, MD, FACC, FAHA, MSCAI, FESC) appeared first on Rethinking Clinical Trials.

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Grand Rounds December 2, 2022: A Randomized Controlled Trial of Mobile Health Intervention in Heart Failure and Diabetes: Lessons Learned (G. Michael Felker, MD, MHS)

Rethinking Clinical Trials

Pragmatic Clinical Trials, Heart Failure, Diabetes. Making lifestyle changes is difficult especially for people living with chronic diseases, where healthy behaviors could make a big difference. This study asks how can we better facilitate health behaviors in patients with chronic diseases and can we leverage technology?

Trials 130
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Grand Rounds October 6, 2023: Hybrid Studies Should Not Sacrifice Rigorous Methods (David M. Murray, PhD; Moderator: Jonathan Moyer, PhD)

Rethinking Clinical Trials

Murray, PhD NIH Associate Director for Prevention and Director, NIH Office of Disease Prevention Moderator: Jonathan C. Moyer, PhD Statistician, NIH Office of Disease Prevention Slides Keywords Implementation; Study design; Hybrid; Clustered; DECIPHeR Key Points People often contest that hybrid designs are not as rigorous as they should be.

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Medicare savings won’t make a dent in healthcare costs

World of DTC Marketing

A study put a price tag on American’s bad eating habits: $50 billion a year in health care costs, attributable to cardiometabolic diseases such as heart disease, stroke, and type 2 diabetes. Then there is the cost of unhealthy Americans.

Drugs 222
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Sarepta’s Elevidys Reaches Finish Line as First Gene Therapy Approved for Duchenne Muscular Dystrophy

XTalks

Symptoms of DMD can include difficulties walking and running, falling frequently, fatigue, learning disabilities/difficulties, heart issues and breathing problems. million price tag of Elevidys, a one-time gene therapy. DMD is caused by the absence of dystrophin, a protein that helps maintain the integrity of muscle cells.