pharmaphorum

JANUARY 24, 2022

IBM said the sell-off is tagged as “a clear next step” as it focuses on its platform-based hybrid cloud and artificial intelligence strategy, but it’s no secret that Watson Health has failed to live up to its early promise.

Radiology 110

Radiology Marketing Genome Genomics 110

XTalks

OCTOBER 12, 2022

We [Philips Pharma Solutions, formerly BioTel Research] have successfully ran multi-site DCE-MRI trials,” said Edward Ashton, PhD, VP, Oncology Imaging, Philips Pharma Solutions. An Example of an Anti-Angiogenic Therapy in Oncology. An Example of an Anti-Vascular Therapy in Oncology. Introduction to Perfusion Imaging.

Clinical Trials 93

Clinical Trials Clinical Trials Trials Drugs 93

The Pharma Data

JANUARY 31, 2021

Utilizing Clover’s proprietary Trimer-Tag© technology, S-Trimer is a trimeric SARS-CoV-2 spike (S)-protein subunit vaccine candidate. About Trimer-Tag© Technology. Trimer-Tag© is an innovative drug development platform which allows the production of novel, covalently-trimerized fusion proteins. —- End —-.

Clinical Trials 52

Clinical Trials Clinical Trials Vaccination Vaccine 52

pharmaphorum

APRIL 27, 2022

AZ’s head of oncology R&D Susan Galbraith said the breakthrough designation “is a significant validation of the potential we see for the historic DESTINY-Breast04 trial to enable a paradigm shift in how breast cancer is classified by targeting the full spectrum of HER2 expression.”

Sales 58

Sales Drugs Antibody Licensing 58

Drug Discovery World

JUNE 14, 2023

We have now our lead product in a Phase I/II study, which is a HER-2 directed tag T cell product for patients with HER-2 positive solid tumours. You can even look at it in from a broader perspective of what is the next breakthrough in oncology. I’ve been with a company for more than five years now.

Research 52

Research Engineer In-Vivo Production 52

pharmaphorum

APRIL 20, 2021

NICE’s final appraisal document for Kesimpta will be followed by technology appraisal guidance (TAG) that will pave the way for NHS prescribing in England and Wales. The Scottish Medicines Consortium is expected to publish its final advice on the drug later this year. billion in sales in 2028.

Sales 110

Sales Medicine Drugs Marketing 110

XTalks

JANUARY 28, 2022

Kimmtrak has a price tag of $18,760 per vial, which amounts to a weekly dose. The company is expecting approval from the European Medicines Agency (EMA) soon as it prepares for a European launch in the second quarter of this year. The median treatment time is about 23 weeks (or 5.3

FDA Approval 98

FDA Approval Development Licensing Licensing 98

The Pharma Data

DECEMBER 3, 2020

Utilizing Clover’s proprietary Trimer-Tag © technology, S-Trimer is a trimeric SARS-CoV-2 spike (S)-protein subunit vaccine candidate. About Trimer-Tag © Technology. Trimer-Tag © is an innovative drug development platform which allows the production of novel, covalently-trimerized fusion proteins.

Vaccination 52

Vaccination Vaccine Immune Response Protein 52

The Pharma Data

JANUARY 31, 2021

Utilizing Clover’s proprietary Trimer-Tag© technology, S-Trimer is a trimeric SARS-CoV-2 spike (S)-protein subunit vaccine candidate. About Trimer-Tag© Technology. Trimer-Tag© is an innovative drug development platform which allows the production of novel, covalently-trimerized fusion proteins.

Vaccination 52

Vaccination Vaccine Trials Protein 52

Drug Discovery World

JANUARY 10, 2023

Our catalog of over 6,500+ primary antibodies, 1,200+ secondary antibodies, and 50+ ELISA kits includes reagents for multiplex IF, flow cytometry, and more in fields including immunology, oncology, and neuroscience. Pillar 5: Protein OE/Epitope Tags. Antibody validation. Pillar 4: Biological Characteristics.

Antibody 52

Antibody Protein Reagent Scientist 52

Delveinsight

FEBRUARY 25, 2021

Combining immuno-oncology treatments such as checkpoint inhibitors with other cancer-killing drugs is considered a remarkable strategy for enhancing the response rate to immunotherapy. Increasing the immune system’s T cells to enhance cancer-destroying capabilities.

DNA 52

DNA In-Vivo Genetics Medicine 52

The Pharma Data

OCTOBER 9, 2021

This designation is predicated on data showing that gantenerumab significantly reduced brain amyloid pillar, a pathological hallmark of Notice, in the ongoing SCarlet RoAD and Marguerite RoAD open- tag extension trials, as well as other studies.

Antibody 52

Antibody In-Vitro Trials Development 52

Rethinking Clinical Trials

MARCH 21, 2023

Goldberg Distinguished Professor and Chief of Oncology Physician-in-Chief, North Carolina Cancer Hospital Director, Cancer Outcomes Research Program University of North Carolina Slides Keywords Patient-reported outcomes, Oncology, Clinical Trials Key Points Symptoms are common in cancer care.

Clinical Trials 130

Clinical Trials Clinical Trials Trials Research 130

The Pharma Data

NOVEMBER 15, 2020

Peng Liang , Founder and Chief Scientific Officer of Clover and inventor of the Trimer-Tag© technology, says, “A successful vaccine that can truly modulate the course of the COVID-19 pandemic must have four essential characteristics: safety, efficacy, scalability of manufacturing, and speed.

Vaccination 52

Vaccination Vaccine Manufacturing Life Science 52

XTalks

AUGUST 17, 2020

Immunotherapy continues to be a burgeoning field, with immune-based therapies being among the leading treatments being developed in oncology and autoimmunity. The beauty with Neo-STAT is that you can make the entire [HLA-based] scaffold along with the IL-2 elements for cancer immunotherapy without a peptide.

Protein 98

Protein Engineer Immune Response In-Vivo 98

XTalks

DECEMBER 21, 2022

The multi-million-dollar price tags are largely attributable to the high R&D and manufacturing costs associated with making a gene therapy, as the raw materials for producing the therapy can be expensive. The majority of gene therapies approved and under development are in the areas of oncology and rare disease.

Life Science 52

Life Science Gene Therapy Gene Clinical Trials 52

pharmaphorum

OCTOBER 4, 2022

The companies tasked with supporting the data needs of the Biobank are Medidata and Theradex Oncology, alongside the NCI. The author of the study noted that researchers from anywhere in the world can now request access to the growing dataset that is being generated by the Biobank effort. Up in the clouds.

Biobanking 105

Biobanking Clinical Trials Clinical Trials Trials 105

Drug Discovery World

NOVEMBER 13, 2023

Jens Fischer, PhD, Program Manager, Large Molecule Research Therapeutic Modalities, Roche Pharma Research and Early Development (pRED), on: ‘ Bispecific and next-generation antibodies for non-oncology indications such as ophthalmologic and neurologic diseases’. It is called, ‘An unexpected future for immune oncology therapies?’

Protein 59

Protein Antibody Engineer Scientist 59

XTalks

JANUARY 19, 2024

This biological variability adds complexity, but with that complexity comes the power to choose the targets, the tags and the payloads and select combinations appropriate to the patient to personalize that therapy. Radiotherapy and Oncology. International Journal of Radiation Oncology* Biology* Physics 76.3 2010): S108-S115.

DNA 66

DNA Radiology FDA Approval Development 66

Drug Discovery World

NOVEMBER 9, 2023

Following this, Rebecca Croasdale-Wood, PhD, Director, Augmented Biologics Discovery & Design, Biologics Engineering, Oncology, AstraZeneca, will present: ‘Benchmarking the impact of AI biologics discovery and optimisation for pharma’. Croasdale-Wood will then participate in a keynote chat, interviewed by Miho.

Engineer 52

Engineer Antibody Protein In-Vivo 52

Delveinsight

DECEMBER 3, 2020

It has been speculated that modifications to the epigenome drive cell ageing, especially a process known as DNA methylation, by which methyl groups are tagged onto DNA. Shinya Yamanaka discovered that the factors could alter the epigenome, and in that way modify mature cells back to a stem cell-like state.

Gene Therapy 52

Gene Therapy Gene Antibody Research 52

XTalks

MARCH 22, 2023

2014 saw multiple business unit buyouts in the industry, with Novartis acquiring GlaxoSmithKline’s oncology arm and Bayer taking over Merck’s consumer health business. In addition, nearly half of all new drugs launched between 2020 and 2021 came with a price tag of $150,000 per year, or more. In 2015, Pfizer acquired Hospira.

Life Science 97

Life Science Drugs FDA Approval Vaccination 97

Rethinking Clinical Trials

JUNE 14, 2023

We’ve also launched a spin-off project called ENCORE which is focused on emulating oncology trials using oncology specialty EHR data. Ongoing work we’re tackling is understanding that the methods and validity of trial emulation using EHR data or EHR-linked claims instead of claims data alone, as we used for these 32 trial emulations.

Clinical Trials 130

Clinical Trials Clinical Trials Trials Research 130

Pharmaceutical Technology

MARCH 17, 2023

Between 2012 and 2022, the number of oncology risk sharing agreements increased massively by 498%. Watt said risk sharing agreements in oncology made up almost 50% of all pharmaceutical risk sharing agreements, as per a GlobalData analysis. This may be because access to oncology drugs varies widely across the world, she added.

Marketing 257

Marketing Drugs Research Analyst Manufacturing 257

The Pharma Data

MAY 4, 2021

Biosimilars, which grew 79% operationally to $530 million, primarily driven by recent oncology monoclonal antibody biosimilar launches of Ruxience (rituximab), Zirabev (bevacizumab) and Trazimera (trastuzumab) globally, as well as continued growth from Retacrit (epoetin) in the U.S.; Adjusted Diluted EPS (2). 47%. . . . . 1,611. . *. *.

Vaccination 40

Vaccination Vaccine Production Sales 40