Remove tag tau
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Roche’s Early Alzheimer’s Blood Test Gets FDA Breakthrough Device Designation

XTalks

The Elecsys pTau217 assay is designed to detect amyloid pathology, a hallmark of Alzheimer’s disease, by measuring phosphorylated tau protein in human plasma. Previously, Roche secured an FDA breakthrough tag for another one of its Alzheimer’s blood tests that detects levels of pTau-181 and ApoE4 (apolipoprotein e4).

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FDA slammed over Aduhelm OK as Biogen takes heat for $56k price tag

pharmaphorum

GlobalData does see the approval of Aduhelm encouraging more research on combination therapies, for example with anti-tau drugs. The post FDA slammed over Aduhelm OK as Biogen takes heat for $56k price tag appeared first on.

Drugs 98
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AAIC 2021: Six Ways the Approval of Aducanumab Will Change Alzheimer’s Clinical Trials

XTalks

Connection with Tau Therapies. Another interesting point that came out of the discussion was how the approval of aducanumab might affect Alzheimer’s clinical trials of anti-tau therapies. She said that while anti-amyloid drugs may be able to impact accumulation of tau, much more data is needed to substantiate that link.

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Biogen’s Aducanumab Becomes First Drug Approved for Alzheimer’s in Nearly 20 Years Despite Controversy

XTalks

The disease is characterized by the accumulation of amyloid beta plaques and neurofibrillary, or tau, tangles in the brain that result in loss of neurons and neural connections. Aducanumab Controversy and Price Tag. Alzheimer’s disease is an irreversible, progressive brain disorder that slowly destroys memory and thinking skills.

Drugs 98
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Viagra ‘should be tested as Alzheimer’s therapy’

pharmaphorum

The model suggested sildenafil users would have a 69% reduced risk of Alzheimer’s compared to non-users, a higher impact than drugs that target amyloid and tau, which have accounted for the bulk of drug discovery and development for the disease in the last couple of decades.

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