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NEW YORK — Amazon said Wednesday it has closed its $3.9 billion acquisition of the primary care organization One Medical.

The e-commerce giant has said the buyout, which was announced in July, is a key component of its growing health care business, which includes its online drugstore Amazon Pharmacy and a patient to doctor messaging service called Amazon Clinic.

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One Medical, which was owned by San Francisco-based 1Life Healthcare Inc, has about 815,000 members and 214 medical offices in more than 20 markets. Its membership-based service offers virtual care as well as in-person visits.

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