April 17, 2025: Researchers Illustrate Potential for Observational Studies of Real-World Data to Emulate Randomized Trials
Rethinking Clinical Trials
APRIL 17, 2025
Researchers applied the “target trial emulation framework” to highlight important design considerations for observational studies that use real-world data to emulate randomized clinical trials. The work, which was supported by the NIH Pragmatic Trials Collaboratory’s Distributed Research Network and by a grant from the National Institute on Aging, was published this week in Alzheimer’s & Dementia: Translational Research & Clinical Interventions.
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