Nine for 2024, Pt 1: From fragility to resilience
pharmaphorum
DECEMBER 20, 2023
In this thought leadership piece by IQVIA EMEA, explore the topic of cardiovascular disease and the strategies needed to shift from fragility to resilience.
topic cardiovascular-disease 
Gatehouse Bio and AstraZeneca to develop RNA therapeutics for heart failure
Pharmaceutical Technology
SEPTEMBER 9, 2022
Initially, the companies partnered to identify new targets for respiratory and cardiovascular diseases using Gatehouse Bio’s artificial intelligence (AI)-powered platform in December 2019. Topic sponsors are not involved in the creation of editorial content.
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21 European countries unite in the EU Joint Action JACARDI to reduce the burden of cardiovascular diseases and diabetes
Sciensano
NOVEMBER 28, 2023
A new four-year project called the Joint Action on Cardiovascular Diseases and Diabetes ( JACARDI ) was launched in Rome on 27 November 2023. These chronic diseases pose a significant threat to individual health and well-being, while also straining healthcare systems and hindering social and economic development.
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GentiBio and BMS partner to develop inflammatory bowel disease therapies
Pharmaceutical Technology
AUGUST 11, 2022
GentiBio and Bristol Myers Squibb (BMS) have signed a multi-year partnership agreement for developing new engineered Treg therapies for inflammatory bowel disease (IBD) patients. Topic sponsors are not involved in the creation of editorial content. According to the agreement, BMS made an undisclosed upfront cash payment to GentiBio. .
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Rocket agrees to acquire biotech firm Renovacor
Pharmaceutical Technology
SEPTEMBER 21, 2022
Renovacor focuses on offering precision treatments for genetic cardiovascular and mechanistically-related ailments. Building on our success in Danon Disease to date, I am particularly excited to expand our cardiology focus and capabilities and address a clear unmet medical need in BAG3-associated dilated cardiomyopathy. for each share.
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March 7, 2023: Webinar on Causal Inference in Pragmatic Trials Coming to IMPACT Collaboratory
Rethinking Clinical Trials
MARCH 7, 2023
In the March 16 session of IMPACT Grand Rounds, the NIA IMPACT Collaboratory will host Dr. Eleanor Murray, who will present on the topic of causal inference in pragmatic trials.
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Driving Tomorrow’s Outcomes Through Clinical Research in Real-World Settings: Essentials of Embedded Pragmatic Clinical Trials: AcademyHealth (June 2023)
Rethinking Clinical Trials
JULY 5, 2023
Session 11 : Next Steps Kevin Weinfurt, PhD Case Study Presentations GGC4H: Testing Feasibility and Effectiveness of Universal Parent-Focused Prevention in Three Healthcare Systems Arne L.
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Changing Trials for Changing Times: Essentials of Embedded Pragmatic Clinical Trials Workshop: Health Care Systems Research Network Conference (February 2023)
Rethinking Clinical Trials
FEBRUARY 23, 2023
Session 11 : Next Steps Wendy Weber, ND, PhD, MPH Case Study Presentations GGC4H: Testing Feasibility and Effectiveness of Universal Parent-Focused Prevention in Three Healthcare Systems Arne L.
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Fried Food Intake May Increase Cardiovascular Disease Risk
The Pharma Data
JANUARY 25, 2021
Fried Food Intake May Increase Cardiovascular Disease Risk. 25, 2021 — Fried food consumption is associated with an increased risk for cardiovascular disease, according to a meta-analysis published online Jan. to 1.43) for major cardiovascular events, 1.22 (95 percent confidence interval, 1.07 Professional.
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Understanding the prevention and treatment needs for cardiovascular disease
pharmaphorum
JANUARY 25, 2022
What does the current picture of cardiovascular disease in Europe look like? Surprisingly for many, cardiovascular disease (CVD) is Europe’s leading cause of death – not cancer, as many people would assume. The post Understanding the prevention and treatment needs for cardiovascular disease appeared first on.
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Lipid Screen, CVD Assessment Advised in Endocrine Disorders
The Pharma Data
OCTOBER 30, 2020
30, 2020 — Lipid screening and cardiovascular risk assessment should be performed for all patients with endocrine disorders, according to an Endocrine Society clinical practice guideline published in the December issue of the Journal of Clinical Endocrinology & Metabolism. Professional. FRIDAY, Oct. Newman, M.D., © 2020 HealthDay.
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Ertugliflozin Noninferior for CV Outcomes in T2DM With ASCVD
The Pharma Data
OCTOBER 15, 2020
15, 2020 — Ertugliflozin is noninferior to placebo with respect to major adverse cardiovascular events among patients with type 2 diabetes and atherosclerotic cardiovascular disease, according to a study published online Oct. The researchers found that a major cardiovascular event occurred in 11.9 THURSDAY, Oct.
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Cardiorespiratory Fitness Linked to Psoriasis, Psoriatic Arthritis
The Pharma Data
JANUARY 15, 2021
15, 2021 — Low cardiovascular fitness in late adolescence is associated with an increased risk for incident psoriasis and psoriatic arthritis among men, according to a study published online Jan. Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox. Professional. FRIDAY, Jan.
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USPSTF Urges Behavioral Counseling to Reduce CVD Risk
The Pharma Data
NOVEMBER 25, 2020
Preventive Services Task Force (USPSTF) recommends offering behavioral counseling interventions that promote healthy diet and physical activity to adults with cardiovascular disease (CVD) risk factors. The researchers found that interventions were associated with a reduced risk for cardiovascular events (pooled relative risk, 0.80).
FDA’s CDRH Launches Voluntary Total Product Life Cycle Advisory Program (TAP) Pilot
XTalks
OCTOBER 26, 2022
The TAP Pilot Soft Launch is the first phase which will begin on January 1, 2023 and will enroll up to 15 devices in the Office of Health Technology 2 (OHT2): Office of Cardiovascular Devices. Give written feedback on requested biocompatibility and sterility topic(s) about the TAP device within 21 days of the request.
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Health Innovators: Sidekick Health’s Saemundur “Sam” Oddsson
pharmaphorum
SEPTEMBER 28, 2021
Watch the video below to hear more on those topics and to find out more about Sidekick Health, its solution and partnerships, plus Sam’s personal advice for budding entrepreneurs. He is also an accomplished researcher and author of several peer-reviewed articles in the areas of obesity, cardiovascular disease and lung disease.
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AHA: Young Adults With CVD Have Low Flu Vaccination Rates
The Pharma Data
NOVEMBER 10, 2020
10, 2020 — Many young adults with cardiovascular disease (CVD) do not receive influenza vaccination, according to a study presented at the American Heart Association Scientific Sessions 2020, held virtually from Nov. The vaccination rate was higher for those with versus without congestive heart disease. Professional.
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AHA: PTSD Tied to Ischemic Heart Disease in Female Veterans
The Pharma Data
NOVEMBER 10, 2020
AHA: PTSD Tied to Ischemic Heart Disease in Female Veterans. 10, 2020 — Posttraumatic stress disorder (PTSD) is an independent predictor of incident ischemic heart disease (IHD) in female veterans, according to a study presented at the American Heart Association Scientific Sessions 2020, held virtually from Nov. Professional.
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CAC Helps ID CVD Risk in Women Receiving RT for Breast Cancer
The Pharma Data
OCTOBER 15, 2020
15, 2020 — For women with breast cancer , coronary artery calcium (CAC) detected on radiotherapy (RT)-planning computed tomography (CT) scan is associated with cardiovascular disease (CVD) risk, according to a study presented at the annual European Breast Cancer Conference, held virtually from Oct. THURSDAY, Oct.
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Webinar Recap: Unleashing the Power of PROs Throughout Oncology Drug Development
VirTrial
FEBRUARY 28, 2024
Topic 1: Modular implementation in phase III, and meeting the needs of all stakeholders Even though we collect data remotely in multiple other therapeutic areas, oncology is not one where we routinely see this employed, so that brings with it the technologies, techniques, and methodologies for remote data collection.
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Can Marketing Save Women’s Healthcare?
Intouch Solutions
MARCH 19, 2024
They are disproportionately affected by cardiovascular disease, autoimmune diseases, migraines and osteoporosis. According to a 2022 KFF Women’s Health study, 44 percent of women with heart disease said their complaints were attributed to psychological causes. Women represent more of the health care system than men.
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Intradialytic Hypotension Tied to Peripheral Artery Disease
The Pharma Data
JANUARY 5, 2021
Intradialytic Hypotension Tied to Peripheral Artery Disease. 5, 2021 — More frequent intradialytic hypotension (IDH) during hemodialysis is associated with a higher incidence of subsequent peripheral artery disease (PAD) diagnosis, according to a study published online Dec. 11 in the A merican Journal of Kidney Diseases.
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Cardiovascular Risk Up With Metabolic Syndrome in Psoriasis
The Pharma Data
DECEMBER 30, 2020
30, 2020 — Metabolic syndrome (MetSyn) is prevalent among patients with psoriasis and is associated with increased cardiovascular risk, according to a study published online Dec. The researchers found that the burden of cardiometabolic disease, systemic inflammation, NCB, and high-risk plaque was higher in the MetSyn group.
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Maternal Heart Health Predicts CVD Onset in Offspring
The Pharma Data
NOVEMBER 6, 2020
6, 2020 — Offspring of parents with ideal cardiovascular health (CVH) have increased cardiovascular disease (CVD)-free survival, with maternal CVH a more robust predictor of offspring’s CVD-free survival than paternal CVH, according to a study published online Nov. Professional. FRIDAY, Nov. Abstract/Full Text.
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Bayer delivers on medical innovation fueling transformation of pharma business
The Pharma Data
FEBRUARY 21, 2022
The company is advancing around 50 projects in ongoing clinical trials across a range of potential therapeutic modalities and indications, with a focus on oncology, cardiovascular and women’s health. Strong pipeline with robust late-stage development program and broad potential across indications.
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Sanofi Pays $3.68 Billion for Principia Biopharma and its MS Pipeline
XTalks
AUGUST 20, 2020
Since BTK is involved in signal transduction in innate and adaptive cells of the immune system, inhibiting its action could help reduce inflammation and tissue damage associated with autoimmune diseases like MS. BTK inhibitor ‘168 is now entering Phase III trials with the first patient having been enrolled in June.
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NewAmsterdam goes public to advance drug in abandoned class
pharmaphorum
JULY 26, 2022
It was a hot topic in cholesterol-lowering drug development a few years ago, but when Merck & Co finally pulled the plug on anacetrapib five years ago on lacklustre phase 3 data, the general consensus was that the drug class was an R&D dead end. Remember CETP?
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More Plant Foods, Less Red Meat May Cut Heart Disease Risk
The Pharma Data
DECEMBER 9, 2020
More Plant Foods, Less Red Meat May Cut Heart Disease Risk. 9, 2020 — Substituting high-quality plant foods such as legumes, nuts, or soy for red meat might reduce the risk for coronary heart disease (CHD), according to a study published online Dec. Professional. WEDNESDAY, Dec. 2 in The BMJ. Laila Al-Shaar, M.P.H.,
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Guidelines Developed for Diabetes Management in CKD
The Pharma Data
NOVEMBER 18, 2020
18, 2020 — In a synopsis of the 2020 Kidney Disease: Improving Global Outcomes (KDIGO) clinical practice guideline, published online Nov. 10 in the Annals of Internal Medicine, recommendations and practice points are presented for clinicians caring for patients with diabetes and chronic kidney disease (CKD). WEDNESDAY, Nov.
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Pfizer Completes Acquisition of Arena Pharmaceuticals
The Pharma Data
MARCH 13, 2022
Acquisition offers new, differentiated, and potentially best-in-class approach to address needs of a broader number of patients with immuno-inflammatory diseases. In particular, we’re hopeful that we can accelerate clinical development of etrasimod successfully to have a positive impact on those living with these debilitating diseases.”.
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COVID-19 Patients More Often Have Vitamin D Deficiency
The Pharma Data
OCTOBER 27, 2020
from the University of Cantabria in Santander, Spain, and colleagues conducted a retrospective case-control study of 216 COVID-19 patients and 197 population-based controls to assess 25OHD levels and examine the influence of vitamin D status on disease severity. Hernández, Ph.D., The researchers found mean 25OHD levels of 13.8 ± 7.2
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A glance back to Pharma Integrates, London 2022 – part ii
pharmaphorum
JANUARY 19, 2023
It was a unique event, at which leaders from across the pharmaceutical pipeline addressed the needs of the industry, shared their own insights, and tackled debates on the crucial topics that influence the future of patient outcomes. Pharma and healthcare together can tackle chronic diseases. It’s our last throw,” Lord Prior explained.
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Statins PROS and CONS [TOP LIST]
Druggist
FEBRUARY 10, 2021
Coronary heart disease (restriction of the blood supply to the heart). Cardiovascular disease (heart attack, angina, heart failure) is one of the leading causes of death in the UK. Statins can be prescribed for patients as primary or secondary prevention of cardiovascular disease (CVD). Statins – pros.
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Vitamin D3, Omega-3 Fatty Acids Have No Impact on AMD
The Pharma Data
OCTOBER 30, 2020
from Brigham and Women’s Hospital in Boston, and colleagues conducted a prespecified ancillary study of the Vitamin D and Omega-3 Trial of supplementation with vitamin D and marine omega-3 fatty acids for the primary prevention of cancer and cardiovascular disease. Christen, Sc.D., years of treatment and follow-up.
FDA accepts Dupixent® (dupilumab) for Priority Review in children aged 6 months to 5 years with moderate-to-severe atopic dermatitis
The Pharma Data
FEBRUARY 13, 2022
FDA a ccepts Dupixent ® (dupilumab) for Priority Review in c hildren a ged 6 m onths to 5 y ears with m oderate-to-severe a topic d ermatitis. Atopic dermatitis is a chronic type 2 inflammatory skin disease, and 85 to 90% of patients develop symptoms (onset of disease) before 5 years of age, which can often continue through adulthood.
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Real-World Implications of Vitamin K2 Deficiency
XTalks
SEPTEMBER 14, 2020
At the same time, 31% of global mortality is attributed to impaired cardiovascular health. He will also be co-presenting an important webinar on this very topic. In fact, one-third of all fall-related deaths are attributed to low bone density, a condition that impacts 200 million women globally. While both are impacted by age (i.e.,
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Ongoing Anticoagulant Use Does Not Avert Severe COVID-19
The Pharma Data
DECEMBER 4, 2020
to 1.33) and in a comparator group of patients with cardiovascular disease (adjusted hazard ratio, 0.94; 95 percent confidence interval, 0.80 Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox. to 1.12] and 0.90 [95 percent confidence interval, 0.71 to 1.15], respectively).
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Pharma TV Ad Spending Trends: Companies in the Top Ten this Week
XTalks
MAY 13, 2021
A study from the Cleveland Clinic showed that 68 percent of Americans decided to make healthy lifestyle changes during the COVID-19 pandemic and pay more attention to risk factors for health concerns, including chronic diseases and mental health issues.
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Masked Asleep Hypertension Common in U.S. Adults
The Pharma Data
NOVEMBER 2, 2020
percent), or chronic kidney disease (21.5 “Future research should investigate the possible cardiovascular risk reduction and economic benefits of treating asleep hypertension,” the authors write. Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox. 65 years; 24.4
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Get Rid of Red Meat to Help Your Heart: Study
The Pharma Data
DECEMBER 7, 2020
On the other hand, opting for plant-based proteins instead of ordering a steak may boost your cardiovascular health. The investigators looked at how red meat consumption influenced their risk of heart disease, the leading cause of death among American men and women. Chan School of Public Health, in Boston. 2 in the BMJ. .
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How transcriptomics is driving drug discovery
Drug Discovery World
FEBRUARY 13, 2023
which genes are upregulated, and which ones are downregulated – which is very useful when studying different disease states. Transcriptomics are a necessary compliment to the development of precision medicine therapy approaches in many different disease areas. SB: Certainly. since October 2021.
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AbbVie’s Rinvoq and Pfizer’s Cibinqo Win FDA Approvals as Eczema Treatments, Bringing Competition to Sanofi’s Dupixent
XTalks
JANUARY 21, 2022
According to Pfizer, up to ten percent of adults and 20 percent of children around the world suffer from eczema, with a third of patients experiencing moderate to severe disease. The trials assessed measures of improvements in skin clearance, itch relief, disease extent and severity. In the US, there are around 6.5
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FDA accepts Dupixent® (dupilumab) for priority review in adults with prurigo nodularis
The Pharma Data
MAY 31, 2022
if approved Acceptance marks another important step in advancing Dupixent for a broad range of diseases with underlying type 2 inflammation. Both trials met the primary and key secondary endpoints, showing Dupixent significantly improved disease signs and symptoms compared to placebo, including reduction in itch and skin lesions.
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Sotyktu (deucravacitinib) Gets FDA Approval for Moderate-to-Severe Plaque Psoriasis
XTalks
SEPTEMBER 16, 2022
People with psoriasis are also at risk of developing additional health conditions, such as cardiovascular disease. Topical therapy , which includes steroid creams, can help address itchy and painful regions on the body for patients with mild disease. We welcome this new treatment option.”.
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