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Changing the way cancer drugs are priced in the U.S. is apparently even harder than it sounds.

EQRx, a company founded to upend the costly U.S. system for pricing new drugs, said Thursday it would abandon that goal for the two products that are closest to the market.

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The company said that it would “adopt market-based pricing” for aumolertinib, a treatment for non-small lung cancer, and lerociclib, a treatment for breast cancer. That is a stark contrast to the plan that EQRx laid out when it was founded three years ago, when the company’s founder and executive chairman, the venture capitalist Alexis Borisy, said that EQRx’s entire purpose would be to reimagine the way that drug pricing works by working more closely with insurers and health care systems to increase the use of lower-priced drugs.

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