Drug Discovery World

MARCH 29, 2023

The trial is expected to enrol 10 patients, aged 18-75 years, who have had a diagnosis of medically refractory UC of at least six months duration and have failed at least one monoclonal antibody therapy. The post First patient dosed in ulcerative colitis drug trial appeared first on Drug Discovery World (DDW).

Drug Trials 52

Drug Trials Trials Drugs Clinical Trials 52

BioSpace

APRIL 1, 2021

One of the common research approaches to treating brain diseases such as Parkinson’s disease (PD) and Alzheimer’s disease (AD) is using antibodies designed to clear the accumulated misfolded proteins implicated in the diseases. To date, these drug trials have not been particularly successful at i.

Protein 73

Protein Drug Trials Antibody Trials 73

Drug Discovery World

FEBRUARY 20, 2023

AstraZeneca’s Evusheld became the first antibody combination for pre-exposure prophylaxis (PrEP) against Covid-19 licensed in the UK. The post What are the top disease areas for clinical drug trials? appeared first on Drug Discovery World (DDW).

Drug Trials 52

Drug Trials Trials Clinical Trials Clinical Trials 52

The Pharma Data

NOVEMBER 10, 2020

We wanted a tau antibody that would bind to the expressed forms of tau, so we developed a very specific assay,” Dage said. The plasma assay elements include: Capture – a biotin-labeled anti-phosphor-thr217-tau antibody. Detection – a ruthenium-labeled isoform-specific anti-tau antibody.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Antibody 52

pharmaphorum

JANUARY 25, 2021

GlaxoSmithKline has suffered another research setback after it axed a phase 2 trial of an anti-LAG3 drug in patients with ulcerative colitis, following a major disappointment with a key lung cancer drug last week. The post GSK suffers another R&D setback, axing ulcerative colitis drug trial appeared first on.

Drug Trials 94

Drug Trials Trials Drugs Licensing 94

Advarra

MARCH 21, 2023

These products will require clinical trial data to get to market, but with significantly fewer participants required as compared to a drug trial. Class 3: Applied to products with the highest risk, or to Class 2 products that are the first in their category. Think of the intent or purpose for the intended use (e.g.,

Clinical Trials 52

Clinical Trials Clinical Trials Trials Production 52

XTalks

APRIL 26, 2021

Given the success of Oxford’s Phase II trial, the study investigators are now gearing up for a Phase III licensure trial to assess large-scale safety and efficacy in 4,800 children aged 5 to 36 months across four countries in Africa. Developing an efficacious vaccine against malaria has been a huge challenge.

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Vaccination Vaccine Immune Response Trials 105