Increasing trial participation for new cancer treatments

Elsevier

As one study put it: “The increasing sophistication of cancer treatments threatens to outpace the ability of health care providers to enroll patients in clinical trials to test those therapies.”. And giving more patients access to trials certainly works to do that.”.

Patient-Centered Trials are Successful Trials

Crucial Data Soutions

In recent years, there have been a lot of conversations about how clinical researchers design and execute clinical trials. Are we still designing trials that rely solely on the participants’ ability to visit study sites?

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Alnylam details anticipated results from heart disease drug trial

Bio Pharma Dive

Fuller data from Alnylam’s APOLLO-B trial confirm the success reported by the company last month, but won’t end a debate on the degree of benefit offered by its drug

Questions Frequently Asked Pertaining to Clinical Trials

Riverside Clinical Research

If you are considering playing a vital role in the advancement of medicine and medical technology by embarking on your first experience as a clinical trial volunteer, you most likely have a few questions about clinical research and the clinical trial process.

What Biotech and Pharma need to consider about decentralized trials

Bio Pharma Dive

The pandemic motivated sponsors to reimagine decentralized trials and realize the benefits these models deliver

Trials 250

Clinical trials face increasing challenges

Bio Pharma Dive

The COVID-19 pandemic emerged at a time when the clinical trial landscape had reached a peak in complexity. Global trials are now commonplace as drug makers seek to establish efficacy in diverse populations

Tackling barriers to diversity, equity, and inclusion in clinical trials

Clairnes

The post Tackling barriers to diversity, equity, and inclusion in clinical trials appeared first on Clinical Trial Recruitment & Management Services.

De-risking oncology trials with medical monitoring

Bio Pharma Dive

Phase three oncology studies have approximately a 35% likelihood of leading to regulatory approval

Trials 274

Why are clinical trials struggling with diversity?

Pharma Phorum

Racial disparities are still commonplace in many clinical trials with white-ethnic groups often overrepresented amongst trial participants. While many pharma companies are actively working on initiatives to improve diversity in clinical trials, we still have a long way to go.

Accelerating virtual clinical trials

Bio Pharma Dive

Leveraging the guidance and support of trial virtualization professionals with experience in key areas of a trial's lifecycle will undoubtedly impact overall success

Practical approaches to operationalizing decentralized clinical trials

Bio Pharma Dive

When appropriate, DCTs can accelerate trial conduct, create a wealth of high-quality data and improve efficiency

Roche, nearing major trial readouts, starts new Alzheimer's drug study

Bio Pharma Dive

A large, multi-year trial is part of that bet As Aduhelm sputters on the market, Roche aims to prove its experimental medicine can work better.

Trials 252

New cancer drug clinical trials struggling

World of DTC Marketing

WHAT’S THIS ABOUT THEN : Researchers are rushing to launch clinical trials of experimental vaccines against the coronavirus, and treatments for COVID-19. Eli Lilly recently announced that it would halt enrolment in ongoing studies and delay the launch of new trials.

Clinical Trial Efficiencies: The Power of a Single Workstream

Imperical Blog

The management time needed to corral many different elements during a trial is immense. And there… The post Clinical Trial Efficiencies: The Power of a Single Workstream appeared first on Imperial Clinical Research Services Blog.

How to address patient privacy and data-security concerns in clinical trials

Clairnes

The post How to address patient privacy and data-security concerns in clinical trials appeared first on Clinical Trial Recruitment & Management Services.

Breaking down the barriers to decentralized trials

Bio Pharma Dive

Decentralized trials are here to stay. Here's how technology has and will continue to pave the way

Trials 236

Merck terminates Lynparza trial in colorectal cancer

Bio Pharma Dive

The setback slows plans to broaden use of a drug that analysts expect to generate nearly $10 billion in annual sales later this decade

Sales 224

Clinical trials: 2021 Recap and take-aways for 2022 and ahead. From Vaccine trials, new regulations, decentralized trials and patient-centricity

Clairnes

The post Clinical trials: 2021 Recap and take-aways for 2022 and ahead. From Vaccine trials, new regulations, decentralized trials and patient-centricity appeared first on Clinical Trial Recruitment & Management Services.

A Cancer Trial’s Unexpected Result: Remission in Every Patient

NY Times

Colon and Colorectal Cancer Drugs (Pharmaceuticals) Clinical Trials Research Immunotherapy American Society of Clinical Oncology New England Journal of Medicine GlaxoSmithKline PLCThe study was small, and experts say it needs to be replicated.

Trials 114

Clinical trial DTC? It may not be right for your drug candidate

World of DTC Marketing

SUMMARY: Over half of all clinical trial sites are outside the U.S. 87 % of all subjects in recent biologics trials were enrolled outside the U.S. DTC may or may not work for clinical trial enrollment it really depends on the condition and risk as judged by the patient.

COVID-19 has changed clinical trials for the better, says Medidata

Pharma Phorum

The pandemic forced clinical trial sponsors to change their processes, with a more technology-driven approach and, according to a new study by Medidata, the sector is now “stronger than ever” as a result.

The right way to use social media for clinical trial recruitment

Clairnes

The post The right way to use social media for clinical trial recruitment appeared first on Clinical Trial Recruitment & Management Services.

Accelerating patient care through digital transformation and decentralized clinical trials

Bio Pharma Dive

The adoption of digital health technologies (DHTs) in the industry continues to pave the way to enable decentralized clinical trials (DCTs

How digital patient recruitment can reduce enrollment costs in Major Depressive Disorder clinical trials

Clairnes

The post How digital patient recruitment can reduce enrollment costs in Major Depressive Disorder clinical trials appeared first on Clinical Trial Recruitment & Management Services.

4 Benefits Of Clinical Trial Participation

Olympian Clinical Research

Clinical trials are research studies designed to evaluate or test a medical, surgical, or behavioral intervention. Most recently, clinical trials have gained recognition through the development and testing of Covid-19 vaccines.

BioMarin reports cancer case in hemophilia gene therapy trial

Bio Pharma Dive

Drug regulators have not ordered a trial hold, however The development comes three weeks after Roctavian was approved in Europe and ahead of a planned regulatory submission in the U.S.

Pfizer gene therapy research delayed by trial changes, safety questions

Bio Pharma Dive

Data readouts for Pfizer's hemophilia gene therapies are now expected later than previously forecast, while the company also works through modifying a trial of its Duchenne treatment

Reimagining Clinical Trials: Why are Virtual Clinical Trials Becoming the New Normal?

Delveinsight

Clinical trials are an essential part of the drug development process. Worldwide, more than 2 million clinical trials are registered and the number is steadily increasing over the past several years. The conduct of trials was not possible due to the risk of catching coronavirus.

Leveraging print and digital communications for patient-centric clinical trials

Bio Pharma Dive

The demand for communicating and reaching trial participants where they live in the most convenient and effective fashion is growing daily and having a dynamic print solution can help make that happen

Decentralized Clinical Trials: the next step towards digitalization of clinical research

Clairnes

The post Decentralized Clinical Trials: the next step towards digitalization of clinical research appeared first on Clinical Trial Recruitment & Management Services. Blog Decentralized Clinical Trials

How to leverage data to boost atopic dermatitis trial registrations

Clairnes

The post How to leverage data to boost atopic dermatitis trial registrations appeared first on Clinical Trial Recruitment & Management Services.

Virtual Reality App trial shown to reduce common phobias

Scienmag

Results from a University of Otago, Christchurch trial suggest fresh hope for the estimated one-in-twelve people worldwide suffering from a fear of flying, needles, heights, spiders and dogs. Social & Behavioral Science app common phobias reality reduce shown trial virtual

Xtalks Spotlight: How are Decentralization Practices Changing CNS Clinical Trials?

XTalks

The adoption of decentralized clinical trial models has gained significant momentum in the past several years, even before the COVID-19 pandemic that triggered the need for more remote options to mitigate trial disruptions. Rachel Colite, VP Decentralized Clinical Trials, Cogstate.

The Apple Watch in clinical trials: Current uses and future possibilities

Bio Pharma Dive

Why the Apple Watch will likely be one of the top choices for use by sponsors, CROs and clinical trial teams wishing to use wearables in their trials

Decentralised trials: beyond the pandemic

Pharma Phorum

The adoption of decentralised activities was a major factor in allowing clinical trials to continue during the early stages of the pandemic. This is where the advantages of DCTs can address the limitations of traditional clinical trials.

HPV and the New Velocity Clinical Research HPV Vaccine Clinical Trial

Riverside Clinical Research

Through vigilant monitoring and testing, the Velocity Clinical Research study team consistently helps develop vital medical interventions that often result in effective treatments and improved quality of life for both our clinical trial volunteers and the greater community as a whole.

Allogene cleared by FDA to resume 'off the shelf' cancer cell therapy trials

Bio Pharma Dive

A "chromosomal abnormality" that led regulators to halt Allogene's trials was judged to be unrelated to its technology, a finding with important implications for the field of donor-derived cell therapies

Nektar, Bristol Myers drug combination fails in late-stage melanoma trial

Bio Pharma Dive

The trial results were the most significant setback for the companies' four-year-old partnership and will likely force Nektar to cut costs

Trials 230

eCOA clinical trials: A simple, cost-effective approach to study build

Bio Pharma Dive

This new data capture model gives clinical trial sponsors control over study build

Pfizer cleared to restart hemophilia gene therapy trial

Bio Pharma Dive

While a voluntary pause in dosing new patients will remain in place, the FDA's decision puts the study back on track to deliver data in 2023

Despite failed trial, Brainstorm asks FDA to approve ALS drug

Bio Pharma Dive

The move comes less than a month after the agency agreed to review Biogen’s tofersen — another ALS drug with a questionable record in clinical testing

Trials 207

Cancer and Clinical Trials: May 20 is Clinical Trials Day

Triage Cancer

Friday, May 20, is Clinical Trials Day! Clinical trials are critical to advancing cancer research, and they also provide opportunities for individuals diagnosed with cancer to try new treatments. And for a more in-depth breakdown, see Triage Cancer’s Quick Guide to Clinical Trials.

How Much Do You Know About in silico Trials?

XTalks

Take this quiz to test your knowledge about in silico trials! Register for this free, upcoming webinar to learn more about the benefits of implementing in silico clinical trials with mechanistic models for drug development.