Why small particles matter: Manufacturing and micro-material contamination
Pharmaceutical Technology
MARCH 6, 2024
To protect patient safety and reduce recall risks, drug manufacturers must reduce particle contamination sources wherever possible.
Contamination Related Topics 
UK MHRA recalls batches of eye gels due to microbial contamination
Pharmaceutical Technology
NOVEMBER 27, 2023
The UK MHRA has issued a recall of batches of carbomer-containing lubricating eye gels due to potential microbial contamination.
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IPC introduces draft amendment to microbial contamination in non-sterile products in IP 2022
AuroBlog - Aurous Healthcare Clinical Trials blog
NOVEMBER 3, 2022
In a bid to control the microbial quality of pharmaceutical products, the Indian Pharmacopoeia Commission (IPC) has come out with a draft amendment to microbial contamination in non-sterile products in Indian Pharmacopoeia (IP) 2022.
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Bayer pulls batch of cancer med Vitrakvi over bacterial contamination concerns
Fierce Pharma
NOVEMBER 20, 2023
The threat of microbial contamination has triggered yet another drug recall, this time from German pharma bigwig Bayer. after routine stability testing discovered the presence of microbial contamination identified as Penicillium brevicompactum. Bayer is recalling one lot of Vitrakvi oral solution in the U.S.
'Contaminated' spinach causes hallucinations in Australia
Medical Xpress
DECEMBER 15, 2022
Health authorities in Australia have said nine people in Sydney suffered "toxic reactions"—including hallucinations—from a batch of spinach thought to contain an "accidental contaminant".
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Keeping cleanrooms clean: Choosing the right laboratory equipment is key
Bio Pharma Dive
APRIL 15, 2024
Because live cell and tissue products are extremely sensitive to contamination from microorganisms, viral particles or other airborne impurities, research and manufacturing involving these materials needs to be conducted in a cleanroom environment.
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Lead contamination surfaces in affluent Atlanta neighborhood
Medical Xpress
MAY 11, 2023
Elizabeth Burns had just come inside from gardening in 2021 when she caught a TV news report about a rocklike material contaminating a nearby community's soil with lead.
Generics maker VistaPharm recalls ulcer med on bacteria contamination fears
Fierce Pharma
SEPTEMBER 25, 2023
shelves thanks to its own contamination scare. . | Drugs tainted with impurities ranging from bacteria and particulates to likely cancer agents have triggered multiple FDA recalls in recent years. Now, Florida’s VistaPharm is pulling a popular ulcer treatment from U.S.
Antibiotic-resistant bacteria contaminates whole ICU, shows study
Medical Xpress
MAY 8, 2023
Carbapenem-resistant Acinetobacter baumannii (CRAB) was brought into the ICU, in Hangzhou, on multiple occasions as patients were admitted, creating a large 'reservoir' of the bacteria which contaminated beds and equipment.
GSK manufacturing review prompts Scynexis to pull Brexafemme, halt trials over contamination concerns
Fierce Pharma
SEPTEMBER 25, 2023
GSK manufacturing review prompts Scynexis to pull Brexafemme, halt trials over contamination concerns esagonowsky Mon, 09/25/2023 - 12:26
Outbreak of typhoid on Dutch ship traced to contaminated drinking water
Medical Xpress
APRIL 1, 2023
A large outbreak of typhoid on a ship in the Netherlands has been traced to contaminated water, this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2023, Copenhagen, April 15-18) will hear.
Breastfeeding may reduce arsenic exposure in infants in arsenic-contaminated areas
Medical Xpress
FEBRUARY 9, 2023
Arsenic contamination is a significant threat to human health in many parts of the world. However, little is known about exactly how arsenic passes between mothers and their babies—both born and unborn—in populations living in contaminated areas.
Multiple indicators of wastewater contamination to shellfish farms
Scienmag
DECEMBER 8, 2021
Food and Drug Administration, tested multiple indicators of wastewater contamination to identify potential sources of contamination […]. A recent study by researchers at the Dauphin Island Sea Lab and the University of South Alabama, in collaboration with the U.S.
Conservationists find high DDT and PCB contamination risk for critically endangered California coastal condors
Scienmag
MAY 18, 2022
A new study has found contaminants that were banned decades ago are still imperiling critically endangered California condors. Credit: Courtesy of San Diego Zoo Wildlife Alliance A new study has found contaminants that were banned […].
WHO urges action on contaminated meds after child deaths
Medical Xpress
JANUARY 24, 2023
Following the deaths of more than 300 children from contaminated cough syrup, the WHO appealed Monday for "immediate and coordinated action" to root out substandard and falsified medicines around the world.
Some food contamination starts in the soil
Scienmag
FEBRUARY 2, 2021
Credit: Matt Limmer When most people hear “food contamination,” they think of bacteria present on unwashed fruits or vegetables, or undercooked meat. However, there are other ways for harmful contaminants to be present in food products.
Infant death linked to contaminated breast pump: CDC
Medical Xpress
MARCH 3, 2023
Cronobacter sakazakii bacteria from a contaminated breast pump caused an infection that killed an infant last year, U.S. federal health officials said Thursday.
Johnson & Johnson Pulls Neutrogena and Aveeno Spray Sunscreens Over Benzene Contamination
XTalks
JULY 16, 2021
Johnson & Johnson is recalling sunscreens from two of its popular brands over concerns of carcinogenic benzene contamination. Therefore, levels should be monitored at different stages of production to avoid harmful benzene contamination. Growing Contamination Issues. Despite this, contamination issues still persist.
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Could used beer yeast be the solution to heavy metal contamination in water?
Scienmag
JUNE 13, 2022
A new analysis by researchers at MIT’s Center for Bits and Atoms (CBA) has found that inactive yeast could be effective as an inexpensive, abundant, and simple material for removing lead contamination from drinking water supplies. Serious […].
Water stagnation: Preventing contamination of water systems in vacated buildings
Pharmaceutical Technology
SEPTEMBER 1, 2022
Corroding pipework that has resulted from stagnation can further contaminate water systems with the presence of metals such as lead and copper. The post Water stagnation: Preventing contamination of water systems in vacated buildings appeared first on Pharmaceutical Technology.
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Arsenic-contaminated water associated with antibiotic resistance in children, study finds
Medical Xpress
DECEMBER 8, 2022
In rural Bangladesh, areas with high levels of arsenic contamination in drinking water, compared to areas with less contamination, have a higher prevalence of antibiotic-resistant Escherichia coli in both water and child stool samples, according to a new study publishing December 8, 2022 in PLOS Pathogens by Mohammad Aminul Islam of Washington State (..)
UMass Amherst chemical engineer receives $1.4M NSF grant to create programmable living devices for drinking water contaminant removal
Scienmag
JUNE 28, 2022
million grant from the National Science Foundation for a collaborative project to engineer synthetic bacteria to neutralize toxic contaminants found in drinking water. Credit: UMass […].
Merck found the source of Januvia contamination, plans to fix the issue this year: report
Fierce Pharma
JANUARY 18, 2023
Merck found the source of Januvia contamination, plans to fix the issue this year: report. Wed, 01/18/2023 - 09:42.
Phase I trial launches into oral drug for radioactive contamination
Drug Discovery World
MAY 17, 2023
A first-in-human clinical trial of an experimental oral drug for removing radioactive contaminants from inside the body has begun. Internal radioactive contamination occurs when radioactive elements are absorbed through wounded skin, inhaled or ingested. Just two drugs are approved for removing internal radioactive contamination.
MIT Scientists Develop Food Sensor That Can Detect Spoiled or Contaminated Food
XTalks
SEPTEMBER 22, 2020
MIT engineers have designed a food sensor , made from an array of silk microneedles, that can pierce through the plastic packaging of foods to sample for bacterial contamination and spoilage. Two kinds of specialized “bioinks” react to the bacterial presence and certain pH levels, which respectively detect contamination and spoilage.
How far is Fukushima nuclear accident contaminated water from us?
Scienmag
DECEMBER 1, 2021
On 26 August 2021, the Japanese Cabinet passed a bill to discharge treated Fukushima nuclear accident contaminated water into the Pacific Ocean to alleviate the problem of nuclear wastewater storage.
Cough syrup can harm children—experts warn of contamination risks
Medical Xpress
FEBRUARY 27, 2023
The organization called for more efforts to protect children from contaminated medicine. The recent deaths of over 300 children in Africa and Asia have prompted the World Health Organization (WHO) to warn about the use of "substandard and falsified" medical products. Toxicologists Winston Morgan and Shazma Bashir unpack the story.
Cross-Contamination of Medications is Wider Issue than Realized: Report
BioSpace
JULY 25, 2021
recent report suggests that cross-contamination is not all that uncommon of an issue, and maybe inevitable.
Mars Recalls Select Skittles, Starbust and Life Saver Gummies over Possible Metal Contamination
XTalks
MAY 19, 2022
Since metal contamination is a common issue in food production, resulting in expensive recalls and lawsuits, the FDA has implemented metal detection standards to ensure the same principles are followed for all companies. So why is metal contamination such a common reason for launching voluntary recalls?
US Woman Receives Revolutionary Brain Implant For OCD And Epilepsy
AuroBlog - Aurous Healthcare Clinical Trials blog
FEBRUARY 6, 2024
American Amber Pearson used to wash her hands until they bled, terrified by the idea of contamination from everyday items, a debilitating result of her obsessive compulsive disorder (OCD).
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Researchers to study possible links between fracking, water contaminants
Scienmag
FEBRUARY 24, 2022
A new grant from HEI Energy will allow researchers to explore possible links between fracking and water contaminants in southwestern Pennsylvania. […].
Prenatal environmental contaminants and childhood disease
Scienmag
MAY 4, 2021
Credit: PAS A state of the art plenary session during the Pediatric Academic Societies (PAS) 2021 Virtual Meeting discussed prenatal environmental contaminants and childhood disease, and the latest evidence for epigenetic mechanisms associated with transgenerational disease and public policy implications.
‘Human error’ at CDMO blamed for contamination of Moderna COVID-19 vaccine
BioPharma Reporter
OCTOBER 6, 2021
A probe has identified 'human errorâ at the Spanish contract development and manufacturing organization, Rovi, as the reason for the presence of metal contaminants in Moderna COVID-19 vaccine doses, leading to Japanese authorities withdrawing 1.6 million doses of the shot in August.
Fecal contamination in popular Montana backcountry area primarily attributable to wildlife or pack animals
Scienmag
SEPTEMBER 22, 2021
Investigators analyzed water samples from a suite of backcountry lake outlets in the Absaroka-Beartooth Wilderness Area of Montana for fecal contamination. Combining a traditional fecal bacterial assay and polymerase chain reaction (PCR), researchers found fecal contamination, but in most cases the […].
Effect of Disposable Elevator Cap Duodenoscopes on Microbial Contamination and Technical Performance of ERCP
JAMA Internal Medicine
JANUARY 22, 2023
This randomized clinical trial determines contamination rates after high-level disinfection and technical performance of duodenoscopes with disposable elevator caps compared with those with standard designs.
FDA cites Emergent for failings at plant that contaminated J&J doses
Bio Pharma Dive
APRIL 22, 2021
A recent nine-day inspection by agency officials found numerous breaches of manufacturing standards and inadequate training for factory employees.
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Biochar from agricultural waste products can adsorb contaminants in wastewater
Scienmag
NOVEMBER 16, 2020
— Biochar — a charcoal-like substance made primarily from agricultural waste products — holds promise for removing emerging contaminants such as pharmaceuticals from treated wastewater. UNIVERSITY PARK, Pa.
FDA lambasts Kilitch for unsanitary manufacturing conditions and issues warning letter to Natco, too
Fierce Pharma
APRIL 10, 2024
FDA chided Kilitch Healthcare India for “poor practices” tied to written procedures around microbial contamination, shoddy lab records, behaviors that could have caused contamination and quality control lapses. . | In a four-observation warning letter issued this week, the U.S.
Hundreds of ready-to-eat foods are recalled over possible listeria contamination
NPR Health - Shots
FEBRUARY 6, 2023
The foods are sold under dozens of different brand names, but all recalled products say Fresh Creative Cuisine on the bottom of the label. The recall affects items sold in nine East Coast states. Image credit: Sarah Silbiger/Getty Images)
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Pesticides commonly used as flea treatments for pets are contaminating English rivers
Scienmag
NOVEMBER 16, 2020
New research reveals widespread contamination, with two neurotoxic pesticides found in concentrations that far exceed accepted safe limits Researchers at the University of Sussex have found widespread contamination of English rivers with two neurotoxic pesticides commonly used in veterinary flea products: fipronil and the neonicotinoid imidacloprid. (..)
SnoreStop NasoSpray is Voluntarily Recalled by Green Pharmaceuticals Due to Microbial Contamination
XTalks
JUNE 14, 2022
FL OZ (9 mL) nasal spray bottles to be contaminated with the bacteria, Providencia rettgeri. California-based Green Pharmaceuticals Inc. is recalling the 2372/21222 lot of their SnoreStop NasoSpray bottles. The US Food and Drug Administration (FDA) found the 0.3
Making sub-visible particles visible
Bio Pharma Dive
MAY 16, 2022
Sub-visible particles can lower the effectiveness of a drug, which is why regulatory authorities are demanding processes be developed, validated and set up in such a way as to minimize all forms of contamination.
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Pfizer's Hospira recall spree bleeds into 2024 with product pulls for multiple hospital drugs in shortage
Fierce Pharma
DECEMBER 27, 2023
After a year plagued by recalls, Pfizer’s sterile injectables unit Hospira seems no closer to righting the ship over its glass-contamination woes. After a year plagued by recalls, Pfizer’s sterile injectables unit Hospira seems no closer to righting the ship over its glass-contamination woes.
High-impact milling: Are you compromising operator safety?
Pharmaceutical Technology
NOVEMBER 8, 2023
Worker safety and prevention of cross-contamination are vital when working with fine powders and toxic ingredients.
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