article thumbnail

Ask the Expert: Adventitious Contamination Control

PharmTech

In this episode of the Ask the Expert video series, Simona Guidi, Associate Director, Cell and Gene Therapies at ProPharma, discusses the options available for controlling adventitious contamination in cell processing and the use of closed processing systems for cell therapy production.

article thumbnail

Limited Chemical Monitoring Data Impedes Global Water Risk Assessments

Scienmag

Conventional water quality assessment programs primarily focus on a narrow spectrum of well-known contaminants, leaving thousands of other substances—many with unknown or poorly understood toxicities—largely unmonitored. The implications for ecosystem and biodiversity conservation are profound.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Innovative Technique Allows In Vivo Creation of CAR T Cells for Cancer and Autoimmune Disease Treatment

Scienmag

The reliance on ex vivo manipulation also exposes cells to potential contamination, and manufacturing variability can impact therapeutic efficacy. Addressing these limitations has been a persistent scientific challenge, one that has inspired new strategies centered on simplifying and streamlining T cell engineering.

In-Vivo 52
article thumbnail

Top 10 Most Innovative Food Companies of 2025, According to Fast Company

XTalks

At the same time, Purdue University introduced a paperbased, loopmediated isothermal amplification biosensor that detects fecal contamination in produce fields in under an hour. In 2024, University of California, Riverside researchers discovered microbes that break down PFAS known as forever chemicals in drinking water.

Protein 93
article thumbnail

How UV/Sulfite Breaks PFAS via Hydrated Electrons

Scienmag

In the relentless battle against environmental pollutants, few challenges loom as large as the persistent contamination caused by per- and polyfluoroalkyl substances, commonly known as PFAS. The broader consequences of these findings resonate deeply in the context of global efforts to mitigate PFAS pollution.

article thumbnail

March 4, 2025: PRIM-ER Team Develops Innovative Statistical Techniques for Stepped-Wedge Trials

Rethinking Clinical Trials

Stepped-wedge designs can be advantageous when simultaneous rollout of the intervention to all clusters is infeasible, or when withholding the intervention from any cluster would be unethical, or when there is a risk of contamination between intervention subjects and control subjects.

Trials 173
article thumbnail

From Lab Bench to Bedside: The Potential of Renewable Polymers to Revolutionize Medicine

Scienmag

Furthermore, ensuring consistent purity and the absence of immunogenic contaminants necessitates robust purification and characterization protocols. These factors collectively contribute to the protracted timeline and elevated costs associated with bringing renewable polymer-based biomaterials to market.