Moderna says its coronavirus vaccine sparks immune response in older people

Bio Pharma Dive

An initial look at the vaccine's effects on the elderly shows those in their 70s had similar responses to those under 55, Moderna told a government panel

The host immune response in COVID-19 and beyond

Pharma Phorum

MeMed CEO Dr. Eran Eden explores the relationship between the host immune response and SARS-CoV-2 infection and how technology could help personalise treatment strategies. One of these involves listening to what the body’s own immune system can tell us.

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Potential cancer therapy may boost immune response

Scienmag

The addition of an anti-inflammatory medication to a common chemotherapy drug may improve immune response in patients by activating cells to fight cancer Credit: Cedars-Sinai LOS ANGELES (EMBARGOED UNTIL DEC.

Study identifies noncoding RNA involved in immune response and sepsis

Scienmag

SARS-CoV-2 curtails immune response in the gut

Scienmag

New understanding of the deleterious immune response in rheumatoid arthritis

Scienmag

Credit: (C) Erica Tandori Researchers within the Biomedicine Discovery Institute at Monash University have made a breakthrough in understanding the role played by high-risk immune genes associated with the development of rheumatoid arthritis (RA).

Study: Antibody Reduces Death in COVID-19 Patients Unable to Mount an Immune Response

BioSpace

?The new data shows REGEN-COV reduced the risk of death in hospitalized patients unable to mount their own immune response by 20

AstraZeneca's COVID-19 Vaccine Boosts Immune Response in Older, Younger Adults

BioSpace

FDA greenlit the restart of AstraZeneca’s Phase III COVID-19 vaccine trial, the company said the preventative medication boosts immune responses in older and younger adults against the novel coronavirus Days after the U.S.

Canadian study investigates immune response and vaccine hesitancy among Canada’s South Asian communities

BioTech 365

Canadian study investigates immune response and vaccine hesitancy among Canada’s South Asian communities Canadian study investigates immune response and vaccine hesitancy among Canada’s South Asian communities HAMILTON, Ontario, June 03, 2021 (GLOBE NEWSWIRE) — The Government of Canada, through its … Continue reading → GlobeNewswire

Triggering tumor antiviral immune response in triple negative breast cancer

Scienmag

14, 2021) – Researchers at Baylor College of Medicine have discovered how therapeutics targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers (TNBC) to trigger tumor cell death and signal the body’s immune response. HOUSTON – (Jan.

Sanofi-GSK COVID-19 Vaccine Hits Snag With Insufficient Immune Response in 50+ Population

BioSpace

The COVID-19 vaccine candidate developed by Sanofi and GlaxoSmithKline hit a snag that will delay the launch of a Phase III study due to an insufficient immune response in older trial patients

Exercise benefit in breast cancer linked to improved immune responses

Scienmag

BOSTON – Exercise training may slow tumor growth and improve outcomes for females with breast cancer – especially those treated with immunotherapy drugs – by stimulating naturally occurring immune mechanisms, researchers at Massachusetts General Hospital (MGH) and Harvard […]. Tumors grew more slowly and responded better to immunotherapy in mice that exercised compared with sedentary mice.

Strong immune responses seen in adults of all ages

The Pharma Data

response in the over-50s, the age group deemed at higher risk for contracting the severe form of the virus. . The interim results from the phase 2 trial on the vaccine, published today, on the contrary, showed a “ strong neutralizing antibody response” ?

Eurofins Launches Quantitative Antibody Test to Measure Immune Response to COVID-19 and Vaccines

BioTech 365

Scientists reveal structural details of how SARS-CoV-2 variants escape immune response

Scienmag

The findings provide direction for future vaccines or therapies that may offer broader protection against variants LA JOLLA, CA–Fast-spreading variants of the COVID-19-causing coronavirus, SARS-CoV-2, carry mutations that enable the virus to escape some of the immune response created naturally or by vaccination.

#news #biotech COVID-flu combo vaccine from Novavax sparks immune response to both viruses in animals

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: COVID-flu combo vaccine from Novavax sparks immune response to both viruses in animals.COVID-flu combo vaccine from Novavax sparks immune response to both viruses in animals arlene.weintraub Mon, … Continue reading → #news

Study: CureVac’s COVID-19 Vaccine Produces Immune Responses in Healthy Volunteers

BioSpace

Newly announced results of a Phase I dose-escalation study show CureVac’s COVID-19 vaccine candidate, CVnCoV, generates noticeable immune responses in healthy volunteers

Infant antibiotic exposure can affect future immune responses toward allergies

Scienmag

Early life exposure to antibotics in utero and through mother’s milk disrupts beneficial gut bacteria, compromising T-cell development, Rutgers research shows Exposure to antibiotics in utero and infancy can lead to an irreversible loss of regulatory T-cells in the colon-a valuable component of the immune system’s response toward allergens in later life – after only […].

Intranasal influenza vaccine Phase 1 study shows strong immune response

BioPharma Reporter

A single-dose intranasal influenza vaccine is safe and produces a durable immune response, according to a Phase 1 study published in the Journal of Clinical Investigation this week.

Many COVID-19 patients produce immune responses against their body’s tissues or organs

Scienmag

A University of Birmingham-led study funded by the UK Coronavirus Immunology Consortium has found that many patients with COVID-19 produce immune responses against their body’s own tissues or organs. COVID-19 has been associated with a variety of unexpected symptoms, both at the time of infection and for many months afterwards. It is not fully understand […]. Infectious Emerging Diseases Immunology/Allergies/Asthma Infectious/Emerging Diseases Medicine/Health

GSK and Sanofi report positive data from COVID-19 vaccine candidate trial: Strong immune responses seen in adults of all ages

BioPharma Reporter

Sanofi and GSK announced today that their COVID-19 vaccine candidate demonstrated strong immune responses across all adult age groups in a Phase 2 trial.

Rhesus macaques develop promising immune response to SARS-CoV-2

Scienmag

Results suggest lasting immunity after infection In a promising result for the success of vaccines against COVID-19, rhesus macaque monkeys infected with the human coronavirus SARS-CoV-2 developed protective immune responses that might be reproduced with a vaccine.

All gas, no brakes: Testosterone may act as ‘brake pedal’ on immune response

Scienmag

In doing so, a WVU researcher has found it could protect men from stomach inflammation Credit: WVU Photo/Brian Persinger Autoimmune diseases have something in common with horses, bachelor’s degrees and daily flossing habits: women are more likely to have them.

Gut’s immune response in COVID-19 may not provide efficient protection of other organs

Scienmag

A study of immune cells circulating in the blood hints the gut’s immune response to COVID-19 infection may not provide sufficient whole-body immunity from the virus Our guts may not provide long-lasting systemic immunity from COVID-19, which is where immune cells circulate through the body to provide protection to other organs, finds a new study […].

AstraZeneca’s COVID-19 Vaccine Delivers Strong Immune Response, Study Confirms

The Pharma Data

AstraZeneca’s COVID-19 vaccine candidate, AZD1222, currently being evaluated in phase 3 global trials, delivers a strong immune response, according to a new UK study.

Study finds that children’s immune response protects against COVID-19

Scienmag

September 21, 2020–(BRONX, NY)–The first study comparing the immune responses of adults and children with COVID-19 has detected key differences that may contribute to understanding why children usually have milder disease than adults.

Theratechnologies Announces New Data Demonstrating Tesamorelin’s Positive Effect on Immune Response Linked to Liver Inflammation

BioTech 365

Theratechnologies Announces New Data Demonstrating Tesamorelin’s Positive Effect on Immune Response Linked to Liver Inflammation Theratechnologies Announces New Data Demonstrating Tesamorelin’s Positive Effect on Immune Response Linked to Liver Inflammation Data presented at ENDO 2021 MONTREAL, March 20, 2021 (GLOBE … Continue reading → GlobeNewswire

SQZ Biotechnologies Initial First-In-Human Data Demonstrates Investigational Cell Therapy is Safe and Can Stimulate Immune Responses in Certain Patients with Advanced or Metastatic HPV16+ Tumors

BioTech 365

Johns Hopkins Scientists Discover Possible Key to Controlling COVID-19 Immune Response

BioSpace

They believe that by inhibiting factor D, it would reduce the inflammatory reactions that make COVID-19 so deadly

Research Roundup: Explaining Rare Immune Response in Children with COVID-19 and More

BioSpace

Every week there are numerous scientific studies published. Here’s a look at some of the more interesting ones

#news #biotech Insights into how COVID outsmarts the gut’s immune response could point to new treatments

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Insights into how COVID outsmarts the gut’s immune response could point to new treatments.Insights into how COVID outsmarts the gut’s immune response could point to new treatments … Continue reading → #news

AstraZeneca’s Vaccine Produced Immune Responses in Older Patients

The Pharma Data

AstraZeneca’s COVID-19 vaccine candidate, AZD1222, elicited immune responses in older coronavirus patients similar to ones generated in younger adults, lending more promise to a vaccine that’s seen as one of the leading contenders in the race to become the first approved COVID-19 vaccine.

Study reveals how long-term infection and inflammation impairs immune response as we age

Scienmag

Cell Stem Cell, 2021, HOUSTON, TX – March 25, 2021 – Humans are born with tens of thousands of hematopoietic stem cells (HSCs) that collectively ensure lifelong production of blood and immune cells that protect us from infections. Credit: Hormaechea-Agulla et al.,

Greenwich LifeSciences Reports Robust Immune Response Phase IIb Data Supporting GP2 Clinical Outcome of 0% Metastatic Breast Cancer Recurrences Over 5 Years of Follow-up

BioTech 365

Greenwich LifeSciences Reports Robust Immune Response Phase IIb Data Supporting GP2 Clinical Outcome of 0% Metastatic Breast Cancer Recurrences Over 5 Years of Follow-up Greenwich LifeSciences Reports Robust Immune Response Phase IIb Data Supporting GP2 Clinical Outcome of 0% Metastatic … Continue reading → Business Wire

COVID-19 vaccines ‘induce robust immune response’ in pregnant women: study

BioPharma Reporter

COVID-19 mRNA vaccines are âhighly effectiveâ in producing antibodies against SARS-CoV-2 in pregnant and lactating women; and also confer protective immunity to newborns, according to a new study.

New research will allow convenient investigation of human innate immune response to viral infections

Scienmag

(Boston)–Researchers from Boston University School of Medicine (BUSM) report the formation of human cells containing a green fluorescent protein or GFP (one of the most important proteins in biology and fluorescence imaging) genetically fused with two interferon stimulated genes (ISGs), namely Viperin and ISG15. This new creation makes these cells highly valuable reagents for reporting […]. Medicine & Health Medicine/Health

#news #biotech China’s Sinovac sees speedy immune response with COVID-19 shot in early trials

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: China’s Sinovac sees speedy immune response with COVID-19 shot in early trials.China’s Sinovac sees speedy immune response with COVID-19 shot in early trials badams Wed, 11/18/2020 – … Continue reading → #news

‘Goldilocks’ neonatal immune response may protect against autism

Scienmag

Mid-range level of immune protein associated with lowest risk Philadelphia, November 10, 2020 – The causes of autism spectrum disorder (ASD) – including genetic and environmental factors – are not entirely understood. Many studies have already shown that serious maternal infection during pregnancy is associated with increased risk for offspring in both people and animals. […].

#news #biotech CureVac links COVID-19 vaccine to immune response, setting it up to enter pivotal trial

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: CureVac links COVID-19 vaccine to immune response, setting it up to enter pivotal trial.CureVac links COVID-19 vaccine to immune response, setting it up to enter pivotal trial … Continue reading → #news

#news #biotech GSK sees ‘robust immune response’ from RSV vaccine hopefuls

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: GSK sees ‘robust immune response’ from RSV vaccine hopefuls.GSK sees ‘robust immune response’ from RSV vaccine hopefuls badams Wed, 10/21/2020 – 04:07 from FierceBiotech: Biotech [link].

Modeling future COVID-19 cases under a variety of immune responses, and with or without vaccines

Scienmag

Their work emphasizes how dependent the future course of the pandemic is on the nature of the adaptive immune response to this virus and on […]. Researchers who adapted standard epidemiological models to explore how the COVID-19 pandemic trajectory might unfold in the next five years report diverse scenarios ranging from recurring severe epidemics to elimination.

Cells sacrifice themselves to boost immune response to viruses

Scienmag

Whether flu or coronavirus, it can take several days for the body to ramp up an effective response to a viral infection. New research appearing in the journal Nature Immunology describes how different cells in the immune system work together, communicate, and – in the case of cells called neutrophils – bring about their own […].

#news #biotech Moderna’s COVID-19 vaccine spurs immune response in older adults

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Moderna’s COVID-19 vaccine spurs immune response in older adults.Moderna’s COVID-19 vaccine spurs immune response in older adults ntaylor Wed, 09/30/2020 – 06:26 from FierceBiotech: Biotech [link].