Moderna says 'bivalent' booster sparks stronger immune response against omicron

Bio Pharma Dive

The biotech claims study results could position its reformulated vaccine as a booster in the fall, though it’s unclear how well the shot can prevent sickness caused by omicron or newer strains of the variant

NIH study finds mixing COVID-19 boosters increases immune response

Bio Pharma Dive

Results suggested Pfizer's and Moderna's vaccines may serve as a more potent booster for those who initially received Johnson & Johnson's shot, although data are limited and preliminary

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

Huddersfield scientists first to show how coronavirus triggers immune response in brain

Scienmag

Social & Behavioral Science brain coronavirus Huddersfield immune response scientists show triggers

Moderna vaccine safe and spurs immune response in kids, company says

Bio Pharma Dive

The trial results should allow the company to ask the FDA for approval of its vaccine in younger children, just as Pfizer nears a crucial decision for its shot in 5- to 11-year olds

Pfizer says coronavirus vaccine is safe and spurs immune response in children

Bio Pharma Dive

The results position Pfizer and BioNTech to seek clearance in children as young as five years old. But the companies haven't yet shared data on a rare heart inflammation associated with their shot that's a concern for regulators

Moderna says its coronavirus vaccine sparks immune response in older people

Bio Pharma Dive

An initial look at the vaccine's effects on the elderly shows those in their 70s had similar responses to those under 55, Moderna told a government panel

Decoding the language of immune responses

Scienmag

Fever, cough, sore throat – symptoms in the spotlight in the era of COVID-19 – are just some of the tell-tale signs of our body’s immune system kicking into action against an unwanted intruder. Whether triggered by an infection, an allergen, or a vaccine, immune responses are driven by a complex array of cellular processes […]. Latest News Decoding immune language responses

Nature article: SARS-CoV-2 disrupts timing of immune response

Scienmag

to downgrade its immune response. In severe COVID-19, however, this messenger is released at the very beginning of the infection, thus blocking the early control of the pathogen by the innate immune system.

Intranasal delivery of AstraZeneca COVID-19 vaccine fails to generate strong immune response

BioPharma Reporter

Intranasal delivery of ChAdOx1 nCoV-19 failed to induce either a consistent mucosal antibody response or a strong systemic immune response, according to results from a Phase 1 clinical trial released today.

The host immune response in COVID-19 and beyond

Pharma Phorum

MeMed CEO Dr. Eran Eden explores the relationship between the host immune response and SARS-CoV-2 infection and how technology could help personalise treatment strategies. One of these involves listening to what the body’s own immune system can tell us.

Vaccine-induced immune response to omicron wanes substantially over time

The Pharma Data

Investigators then evaluated immune responses over time. Moreover, immune responses to Omicron in all groups waned substantially, with neutralizing antibody levels decreasing 2.4-

Potential cancer therapy may boost immune response

Scienmag

The addition of an anti-inflammatory medication to a common chemotherapy drug may improve immune response in patients by activating cells to fight cancer Credit: Cedars-Sinai LOS ANGELES (EMBARGOED UNTIL DEC.

Scientists blueprint bacterial enzyme believed to “stealthily” suppress immune response

Scienmag

Scientists have produced the first fine-detail molecular blueprints of a bacterial enzyme known as Lit, which is suspected to play a “stealthy” role in the progression of infection by reducing the immune response. Blueprints such as these allow drug designers to uncover potential weaknesses in bacterial arsenals as they seek to develop new therapeutics that […].

Strong immune response underlies acute kidney injury related to COVID-19

Scienmag

— Mayo Clinic researchers have found that acute kidney injury associated with COVID-19 resembles sepsis-caused kidney injury, and the immune response triggered by the infection plays a pivotal role. ROCHESTER, Minn. The findings, published in Mayo Clinic Proceedings, also suggest that mitochondrial dysfunction — a loss of function in cellular energy production — is commonly […]. Infectious Emerging Diseases Infectious/Emerging Diseases Medicine/Health

Pfizer and BioNTech Announce Omicron-Adapted COVID-19 Vaccine Candidates Demonstrate High Immune Response Against Omicron

BioTech 365

Genetic ancestry shapes immune response to influenza virus

Scienmag

A new study aimed at explaining differential susceptibility to viral epidemics reveals that ancestry and associated genetic variation can explain population-level differences in the immune response to the flu virus and perhaps also to COVID-19. Latest News ancestry genetic immune influenza response shapes virus

Study identifies noncoding RNA involved in immune response and sepsis

Scienmag

New understanding of the deleterious immune response in rheumatoid arthritis

Scienmag

Credit: (C) Erica Tandori Researchers within the Biomedicine Discovery Institute at Monash University have made a breakthrough in understanding the role played by high-risk immune genes associated with the development of rheumatoid arthritis (RA).

Physical activity could boost your immune response to the flu jab, according to new systematic review and meta-analysis

Scienmag

Mathematics activity boost flu immune jab Metaanalysis Physical response review Systematic

Covid-19 induced immune response may damage brain, NINDS study finds

Pharmaceutical Technology

Scientists at the National Institutes of Health (NIH) unit National Institute of Neurological Disorders and Stroke (NINDS) have found that Covid-19-induced immune response could damage the blood vessels of the brain and may lead to short and long-term neurological symptoms. .

AstraZeneca’s COVID-19 Vaccine Delivers Strong Immune Response, Study Confirms

The Pharma Data

AstraZeneca’s COVID-19 vaccine candidate, AZD1222, currently being evaluated in phase 3 global trials, delivers a strong immune response, according to a new UK study.

AstraZeneca's COVID-19 Vaccine Boosts Immune Response in Older, Younger Adults

BioSpace

FDA greenlit the restart of AstraZeneca’s Phase III COVID-19 vaccine trial, the company said the preventative medication boosts immune responses in older and younger adults against the novel coronavirus Days after the U.S.

3D-Printed Vaccine Patch Offers Enhanced Immune Response, Comfort Level

BioSpace

The patch is not only painless, it requires less vaccine to generate the same or greater effects

Cedars-Sinai investigators ID gene critical to human immune response

Scienmag

Cedars-Sinai investigators have identified a gene that plays an essential role in the innate human immune system. The gene, NLRP11, helps activate the inflammatory response that tells the body’s white blood cells to go on the attack against a foreign presence. Latest News CedarsSinai critical gene human immune investigators response

Pfizer and BioNTech Announce Updated Clinical Data for Omicron BA.4/BA.5-Adapted Bivalent Booster Demonstrating Substantially Higher Immune Response in Adults Compared to the Original COVID-19 Vaccine

The Pharma Data

Acclimated Bivalent Booster Demonstrating mainly Advanced Immune Response in Grown-ups Compared to the Original COVID- 19 Vaccine Bivalent supporter inspired roughly4-fold advanced negativing antibody titers against OmicronBA.4/BA.5 Immune responses againstBA.4/BA.5

New Data Highlight Immune Response to COVID-19 Vaccines in Individuals with Relapsing Forms of Multiple Sclerosis Treated with Zeposia (ozanimod)

BioTech 365

New Data Highlight Immune Response to COVID-19 Vaccines in Individuals with Relapsing Forms of Multiple Sclerosis Treated with Zeposia (ozanimod) New Data Highlight Immune Response to COVID-19 Vaccines in Individuals with Relapsing Forms of Multiple Sclerosis Treated with Zeposia (ozanimod) … Continue reading → Business Wire

Study: Antibody Reduces Death in COVID-19 Patients Unable to Mount an Immune Response

BioSpace

?The new data shows REGEN-COV reduced the risk of death in hospitalized patients unable to mount their own immune response by 20

Wistar scientists identify novel therapeutic approach to re-activate immune response against tumors

Scienmag

Therefore, new therapeutic options such as targeted therapy that boosts antitumor immunity are needed to improve ovarian cancer treatment efficacy and patient survival. Biology approach identify immune reactivate response scientists therapeutic tumors Wistar

AstraZeneca’s Vaccine Produced Immune Responses in Older Patients

The Pharma Data

AstraZeneca’s COVID-19 vaccine candidate, AZD1222, elicited immune responses in older coronavirus patients similar to ones generated in younger adults, lending more promise to a vaccine that’s seen as one of the leading contenders in the race to become the first approved COVID-19 vaccine.

Sanofi-GSK COVID-19 Vaccine Hits Snag With Insufficient Immune Response in 50+ Population

BioSpace

The COVID-19 vaccine candidate developed by Sanofi and GlaxoSmithKline hit a snag that will delay the launch of a Phase III study due to an insufficient immune response in older trial patients

How a receptor shapes the immune response

Scienmag

Immune cells specialize to ensure the most efficient defense against viruses and other pathogens. Researchers at the University of Basel have shed light on this specialization of T cells and shown that it occurs differently in the context of an acute and a chronic infection. This could be relevant for new approaches against chronic viral […]. Biology Immunology/Allergies/Asthma Medicine/Health Molecular Biology Virology

Strong immune responses seen in adults of all ages

The Pharma Data

response in the over-50s, the age group deemed at higher risk for contracting the severe form of the virus. . The interim results from the phase 2 trial on the vaccine, published today, on the contrary, showed a “ strong neutralizing antibody response” ?

SARS-CoV-2 curtails immune response in the gut

Scienmag

Infant antibiotic exposure can affect future immune responses toward allergies

Scienmag

Early life exposure to antibotics in utero and through mother’s milk disrupts beneficial gut bacteria, compromising T-cell development, Rutgers research shows Exposure to antibiotics in utero and infancy can lead to an irreversible loss of regulatory T-cells in the colon-a valuable component of the immune system’s response toward allergens in later life – after only […].

Seneca Therapeutics Announces Publication of AACR Abstract Demonstrating Systemic Anti-Tumor Immune Response in Syngeneic Pancreatic Murine Model

BioTech 365

Study: CureVac’s COVID-19 Vaccine Produces Immune Responses in Healthy Volunteers

BioSpace

Newly announced results of a Phase I dose-escalation study show CureVac’s COVID-19 vaccine candidate, CVnCoV, generates noticeable immune responses in healthy volunteers

MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio

BioTech 365

MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio MeMed BV® test recently … Continue reading → GlobeNewswire

MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio

BioTech 365

MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio MeMed BV® test recently … Continue reading → GlobeNewswire

MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio

BioTech 365

MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio MeMed BV® test recently … Continue reading → GlobeNewswire

Mix-and-Match Vaccine Platform May Boost Immune Response & Duration

BioSpace

IDRI is working with a newly-formed consortium to develop a next-gen COVID-19 vaccine that will be stable at routine temperatures and that may be able to confer immunity for a longer duration

Press Release: Sanofi-GSK next-generation COVID-19 booster delivers strong immune response against variants of concern, including Omicron

BioTech 365

Press Release: Sanofi-GSK next-generation COVID-19 booster delivers strong immune response against variants of concern, including Omicron Press Release: Sanofi-GSK next-generation COVID-19 booster delivers strong immune response against variants of concern, including Omicron Sanofi–GSK next-generation COVID-19 booster delivers strong immune response … Continue reading → GlobeNewswire

Immune response to COVID-19 vaccine different with prior infection

Scienmag

A quick stick in the arm with an approved COVID-19 vaccine elicits a flurry of activity in the body’s immune system. Biology COVID19 immune infection prior response vaccine

Gut’s immune response in COVID-19 may not provide efficient protection of other organs

Scienmag

A study of immune cells circulating in the blood hints the gut’s immune response to COVID-19 infection may not provide sufficient whole-body immunity from the virus Our guts may not provide long-lasting systemic immunity from COVID-19, which is where immune cells circulate through the body to provide protection to other organs, finds a new study […].