BioPharma Reporter

OCTOBER 11, 2022

Intranasal delivery of ChAdOx1 nCoV-19 failed to induce either a consistent mucosal antibody response or a strong systemic immune response, according to results from a Phase 1 clinical trial released today.

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Bio Pharma Dive

JUNE 8, 2022

The biotech claims study results could position its reformulated vaccine as a booster in the fall, though it’s unclear how well the shot can prevent sickness caused by omicron or newer strains of the variant.

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Medical Xpress

JANUARY 23, 2023

A recent study from a team of researchers from the University of Nebraska–Lincoln and other institutions, however, has found that a subset of taste cells called type II taste cells may play a key role in the body's immune response to harmful oral microbes.

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Bio Pharma Dive

OCTOBER 13, 2021

Results suggested Pfizer's and Moderna's vaccines may serve as a more potent booster for those who initially received Johnson & Johnson's shot, although data are limited and preliminary.

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Medical Xpress

APRIL 26, 2023

A new study by investigators from the Smidt Heart Institute at Cedars-Sinai suggests long COVID-19 might be caused by a dysfunction of the immune system.

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Medical Xpress

DECEMBER 13, 2022

Within a study by investigators at Weill Cornell Medicine and NewYork-Presbyterian, the long-term immune response to SARS-CoV-2 mRNA vaccination was similar in pregnant individuals and non-pregnant individuals of reproductive age.

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Medical Xpress

APRIL 13, 2023

As a major component of the immune system, T cells play a critical role in fighting off viral infections. A team led by Prof. Thomas Brocker and Jan Kranich from LMU's Biomedical Center has demonstrated in a mouse model that so-called extracellular vesicles play an important part in the stimulation of these cells.

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Bio Pharma Dive

OCTOBER 25, 2021

The trial results should allow the company to ask the FDA for approval of its vaccine in younger children, just as Pfizer nears a crucial decision for its shot in 5- to 11-year olds.

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Medical Xpress

OCTOBER 6, 2022

Findings from a small study of eight patients published in Clinical Infectious Diseases suggest that COVID-19 rebound is likely not caused by impaired immune responses.

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Scienmag

JUNE 2, 2022

Fever, cough, sore throat – symptoms in the spotlight in the era of COVID-19 – are just some of the tell-tale signs of our body’s immune system kicking into action against an unwanted intruder. Whether triggered by an infection, an allergen, or a vaccine, immune responses are driven by a complex array of cellular processes […].

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Bio Pharma Dive

SEPTEMBER 20, 2021

The results position Pfizer and BioNTech to seek clearance in children as young as five years old. But the companies haven't yet shared data on a rare heart inflammation associated with their shot that's a concern for regulators.

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Bio Pharma Dive

AUGUST 26, 2020

An initial look at the vaccine's effects on the elderly shows those in their 70s had similar responses to those under 55, Moderna told a government panel.

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Scienmag

OCTOBER 25, 2021

to downgrade its immune response. In severe COVID-19, however, this messenger is released at the very beginning of the infection, thus blocking the early control of the pathogen by the innate immune system. Once an infection is under control, the body normally uses a biochemical messenger known as TGF?

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Immune Response Medicine 96

Medical Xpress

JANUARY 4, 2023

In a new study by researchers from Mass General Brigham's founding members, Brigham and Women's Hospital and Massachusetts General Hospital, a team extensively investigated the immune response of 16 adolescents and young adults who developed myocarditis after receipt of the COVID mRNA vaccine.

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Medical Xpress

OCTOBER 19, 2022

Rheumatoid arthritis is a chronic autoimmune disease that is associated with aberrant immune responses.

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Medical Xpress

SEPTEMBER 9, 2022

New research has suggested that recommended vaccinia virus (VACV)-based vaccines will mount a robust immune response against the monkeypox virus observed in the current outbreak (MPXV-2022).

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Immune Response Vaccination Vaccine Research 75

pharmaphorum

MARCH 15, 2021

MeMed CEO Dr. Eran Eden explores the relationship between the host immune response and SARS-CoV-2 infection and how technology could help personalise treatment strategies. This is made possible using ‘Advanced Host Immune Response Technologies’. The pace of work in the industry reached almost ludicrous speeds.

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Medical Xpress

APRIL 20, 2023

A new HIV vaccine from Scripps Research has shown a significantly improved ability to neutralize the virus in preclinical tests, and it will soon be studied in healthy people who volunteer to participate in clinical trials.

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Bio Pharma Dive

APRIL 11, 2023

The shot appears to generate an immune response that matches or exceeds existing vaccines, but investigators aren’t yet sure how well it can prevent illness.

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BioSpace

DECEMBER 10, 2020

The COVID-19 vaccine candidate developed by Sanofi and GlaxoSmithKline hit a snag that will delay the launch of a Phase III study due to an insufficient immune response in older trial patients.

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Immune Response Vaccination Vaccine Trials 111

Medical Xpress

APRIL 19, 2023

Cancer drugs that stimulate the body's immune system to attack tumors are a promising way to treat many types of cancer. However, some of these drugs produce too much systemic inflammation when delivered intravenously, making them harmful to use in patients.

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BioSpace

OCTOBER 26, 2020

FDA greenlit the restart of AstraZeneca’s Phase III COVID-19 vaccine trial, the company said the preventative medication boosts immune responses in older and younger adults against the novel coronavirus. Days after the U.S.

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BioSpace

NOVEMBER 1, 2020

Newly announced results of a Phase I dose-escalation study show CureVac’s COVID-19 vaccine candidate, CVnCoV, generates noticeable immune responses in healthy volunteers.

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Scienmag

NOVEMBER 25, 2021

A new study aimed at explaining differential susceptibility to viral epidemics reveals that ancestry and associated genetic variation can explain population-level differences in the immune response to the flu virus and perhaps also to COVID-19. Viruses are among the strongest sources of selection pressure in human evolution.

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Scienmag

JUNE 15, 2022

Physical activity could boost your immune response to the flu jab, according to new systematic review and meta-analysis Credit: Anupam Mahapatra, Unsplash, CC0 ([link] Physical activity could boost your immune response to the flu jab, according to new systematic review and meta-analysis ### Article URL: [link] Article Title: Physical activity and (..)

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BioSpace

JUNE 15, 2021

?The new data shows REGEN-COV reduced the risk of death in hospitalized patients unable to mount their own immune response by 20%.

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Scienmag

JULY 12, 2021

Scientists have produced the first fine-detail molecular blueprints of a bacterial enzyme known as Lit, which is suspected to play a “stealthy” role in the progression of infection by reducing the immune response.

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Medical Xpress

MARCH 30, 2023

Aging (senescent) cells, which stop dividing but don't die, can accumulate in the body over the years and fuel chronic inflammation that contributes to conditions such as cancer and degenerative disorders.

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Immune Response Research 111

Medical Xpress

OCTOBER 14, 2022

New findings publishing on October 14 in the journal Immunity show that this is caused by increased expression of an antiviral cytokine type I interferon (IFN-I), which is partially coded for by chromosome 21.

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Immune Response 75

pharmaphorum

SEPTEMBER 7, 2020

A trial of Russia’s Sputnik V coronavirus vaccine has shown the jab produces an immune response, although the study was too small to produce conclusive findings, particularly on safety. The post Early data shows Russia’s Sputnik V COVID-19 vaccine produces immune response appeared first on.

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Medical Xpress

APRIL 6, 2023

The human body is capable of creating a vast, diverse repertoire of antibodies—the Y-shaped sniffer dogs of the immune system that can find and flag foreign invaders.

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Immune Response Antibody Research 145

Medical Xpress

NOVEMBER 24, 2022

Lipids influence how our cells behave and function, which affects many processes in the body including the immune system. When we consume fats (also called lipids) in our diet, they can be metabolized or stored to provide energy for the body. But they are also involved in regulating the genes expressed within—and the signaling between—cells.

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Scienmag

JULY 20, 2021

— Mayo Clinic researchers have found that acute kidney injury associated with COVID-19 resembles sepsis-caused kidney injury, and the immune response triggered by the infection plays a pivotal role. ROCHESTER, Minn.

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Scienmag

FEBRUARY 1, 2021

A long noncoding RNA regulates the expression of inflammatory genes and has a surprising effect on vulnerability to septic shock in mice Credit: Apple Vollmers When the body’s immune response to an infection gets out of control, the result can be sepsis, a life-threatening condition in which an overwhelming inflammatory response can lead rapidly (..)

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Bio Pharma Dive

NOVEMBER 14, 2022

New results show the two-pronged booster the FDA cleared in August sparks a stronger immune response against omicron and its subvariants than Moderna’s original shot.

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The Pharma Data

OCTOBER 26, 2020

AstraZeneca’s COVID-19 vaccine candidate, AZD1222, elicited immune responses in older coronavirus patients similar to ones generated in younger adults, lending more promise to a vaccine that’s seen as one of the leading contenders in the race to become the first approved COVID-19 vaccine. Source link.

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The Pharma Data

MAY 17, 2021

The interim results from the phase 2 trial on the vaccine, published today, on the contrary, showed a “ strong neutralizing antibody response” ? The companies also noted a high immune response after a single dose of the shot in patients with prior infection, indicating, they said, strong booster potential for the jab. “

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