Scienmag

JUNE 23, 2025

The research team employed a series of clever biochemical and genetic engineering strategies to install a miniature synthetic pathway capable of performing this rearrangement under physiological conditions without disrupting cellular integrity. That this reaction can now be coaxed to proceed inside a living E.

Engineer 52

Engineer In-Vivo Reagent Genetic Engineering 52

Scienmag

JULY 5, 2025

The current research evaluates whether intra-arterial administration of tenecteplase – a genetically engineered variant of tPA (tissue plasminogen activator) with enhanced fibrin specificity and prolonged half-life – can potentiate the benefits of thrombectomy without compromising safety.

Genetic Engineering 45

Genetic Engineering Trials Engineer Clinical Trials 45

XTalks

NOVEMBER 29, 2024

Poseida’s genetic engineering platforms stand out for their precision, safety and potential to open new therapeutic avenues. Kristin Yarema, President of Cell Therapy at Poseida Therapeutics – Xtalks Life Science Podcast Ep. These resources allow for scalable cell therapy production, ensuring affordability and broader access.

Gene Therapy 100

Gene Therapy Gene Gene Editing Genetic Engineering 100

Scienmag

JULY 2, 2025

By employing mouse models genetically engineered to lack Rev-erbα specifically in muscle tissue, the authors established that the loss of this receptor severely impairs the time-dependent benefits typically gained from chronic exercise.

Gene Expression 59

Gene Expression Gene Regulation In-Vivo 59

Medical Xpress

JULY 1, 2025

Melanin can either protect or worsen hereditary hearing loss depending on genetic context, as reported by researchers from Japan.

Genetic Engineering 71

Genetic Engineering Genetics Engineer Gene 71

Scienmag

JUNE 20, 2025

By using sophisticated genetic engineering techniques, the researchers generated infant mice with targeted, inducible TBX4 disruption after birth, allowing them to parse the direct consequences of TBX4 deficit on lung maturation and pulmonary vascular integrity.

Genetics 59

Genetics Gene Development Regulation 59

Scienmag

JUNE 9, 2025

The malignant complexity of HGSC is underscored by a heterogeneous genetic landscape marked by extensive genomic instability and multiple aberrations, among which alterations in CDK12 have now gained considerable attention. The crux of the study centers on genetically engineered murine models replicating human HGSC features.

Genetics 85

Genetics Genomics Genome Gene 85

Scienmag

JULY 8, 2025

Disruption of interleukin-4 receptor (IL-4R) signaling—either via receptor blockade or through genetically engineered STAT6 deficiency—resulted in an abrogation of IL-10-producing Th2 cells.

Immune Response 59

Immune Response Genetic Engineering Gene Expression Regulation 59

XTalks

JUNE 23, 2025

The decision, announced June 18, 2025, follows concerns that participants may not have been informed about how their cells would be handled or that their cells could be genetically engineered abroad and re-infused into their bodies in the US.

Clinical Trials 95

Clinical Trials Clinical Trials Trials Gene Therapy 95

Scienmag

JUNE 25, 2025

In a groundbreaking advancement poised to revolutionize the future of crop genetic engineering, scientists have unveiled a novel method for delivering CRISPR–Cas9 genome-editing tools into wheat plants using an RNA virus-based vector.

RNA 59

RNA Genomics Genome Gene Editing 59

Scienmag

JULY 16, 2025

Intriguingly, this strategy circumvents the need for identifying and deploying multiple resistance genes tailored to different pathogens, simplifying the breeding and genetic engineering process.

Engineer 59

Engineer Bacteria Immune Response Genetic Engineering 59

NY Times

JULY 18, 2025

The regulator had asked Sarepta Therapeutics to halt all shipments of its therapy, Ele­vidys, after three patients died from liver failure after taking it or a similar treatment.

Regulation 61

Regulation Drugs Genetic Engineering Clinical Trials 61

Scienmag

JUNE 20, 2025

Methodologically, the researchers employed state-of-the-art biochemical and genetic approaches, including site-specific mutagenesis to alter lysine acetylation sites on OsECT3, mass spectrometry for acetylation mapping, RNA immunoprecipitation assays to assess m^6A binding, and cold tolerance assays in genetically engineered rice lines.

Regulation 94

Regulation RNA Gene Expression Protein 94

Scienmag

JUNE 6, 2025

Understanding these molecular transport systems provides a foundational framework for breeding strategies and genetic engineering aimed at developing plants with optimized nutrient uptake efficiencies.

Protein 69

Protein Regulation Genetic Engineering Research 69

Scienmag

JULY 14, 2025

There is also exciting scope to explore how environmental variables influence these wound healing dynamics and to leverage this knowledge for innovative crop genetic engineering aimed at enhancing resilience.

Hormones 59

Hormones Regulation Genetic Engineering Engineer 59

Pharmaceutical Technology

APRIL 22, 2024

Discover how Synlogic Inc's patented genetically engineered bacteria produce short-chain fatty acids to combat metabolic diseases. Learn more about this innovative treatment approach.

Genetic Engineering 130

Genetic Engineering Bacteria Engineer Genetics 130

Pharmaceutical Technology

MARCH 29, 2024

Discover the groundbreaking patent by Yield10 Bioscience Inc for a genetically engineered oilseed plant expressing a plant protein, revolutionizing biotechnology in agriculture.

Genetic Engineering 130

Genetic Engineering Engineer Genetics Protein 130

Drug Patent Watch

MAY 2, 2022

DrugPatentWatch has been named to Genetic Engineering News‘ Best of the Web list. The review by Genetic Engineering News profile highlighted the “new training modules designed to help you find….

Genetic Engineering 106

Genetic Engineering Engineer Genetics 106

Pharmaceutical Technology

SEPTEMBER 8, 2024

Interferon alfa-2b is under clinical development by Center for Genetic Engineering and Biotechnology and currently in Phase II for Genital Warts (Condylomata Acuminata).

Genetic Engineering 100

Genetic Engineering Engineer Genetics Clinical Development 100

Pharmaceutical Technology

JUNE 10, 2023

CIGB-128 is under clinical development by Center for Genetic Engineering and Biotechnology and currently in Phase I for Brain Tumor. According to GlobalData, Phase I drugs for Brain Tumor does not have sufficient historical data to build an indication benchmark PTSR for Phase I.

Genetic Engineering 100

Genetic Engineering Engineer Genetics Clinical Trials 100

Pharmaceutical Technology

JUNE 10, 2023

CIGB-128 is under clinical development by Center for Genetic Engineering and Biotechnology and currently in Phase I for Brain Tumor. According to GlobalData, Phase I drugs for Brain Tumor does not have sufficient historical data to build an indication benchmark PTSR for Phase I.

Genetic Engineering 100

Genetic Engineering Engineer Genetics Clinical Trials 100

AuroBlog - Aurous Healthcare Clinical Trials blog

AUGUST 7, 2023

New research from ETH Zürich in Switzerland could see future wearable devices (with perhaps a few implants and a touch of genetic engineering) boost our health directly. Fitness trackers help you stay healthy by keeping count of your steps and monitoring your heart rate, driving you on to hit those cardio goals.

Genetic Engineering 246

Genetic Engineering Gene Engineer Genetics 246

Pharmaceutical Technology

MARCH 28, 2024

Discover how Synlogic Inc's patented genetically programmed microorganisms can modulate and treat diseases. Learn about the innovative method for producing pharmaceutical compositions using non-pathogenic bacteria to metabolize phenylalanine. Explore the potential applications in gut microbiome and tumor environments.

Bacteria 130

Bacteria Genetic Engineering Genetics Engineer 130

Scienmag

OCTOBER 16, 2020

International research team including University of Göttingen explains advantages of molecular breeding methods Credit: M Qaim More than two billion people worldwide suffer from micronutrient malnutrition due to deficiencies in minerals and vitamins.

Genetic Engineering 98

Genetic Engineering Engineer Genetics Development 98

Pharma Times

SEPTEMBER 21, 2022

A new genetically engineered virus has delivered a one-two punch in initial phase 1 trial

Genetics 156

Genetics Genetic Engineering Engineer Trials 156

Pharmaceutical Technology

MAY 10, 2023

SYNB1934 consumes Phe in the gastrointestinal (GI) tract by leveraging genetic engineering of the drug or drug-carrying capsule, probiotic escherichia coli (E coli) Nissle. The orally administered, non-systemically absorbed drug candidate SYNB1934 has been designed for reducing blood phenylalanine (Phe) levels in PKU patients.

Genetic Engineering 261

Genetic Engineering Drugs Engineer Genetics 261

BioSpace

DECEMBER 4, 2020

Has China discovered a super-soldier formula through the capabilities of genetic engineering? government official claims this is exactly what is happening.

Genetic Engineering 145

Genetic Engineering Engineer Genetics 145

Pharmaceutical Technology

SEPTEMBER 23, 2024

Learn how their innovative method enhances genetic engineering and biotechnology. Discover Telesis Bio Inc.'s s groundbreaking patent for synthesizing specific DNA sequences.

DNA 130

DNA Genetic Engineering Engineer Genetics 130

Pharmaceutical Technology

SEPTEMBER 5, 2022

Administered as a single dose, the genetically engineered vaccine has the replication-defective adenovirus type 5 vector that expresses the spike S protein of the SARS-CoV-2 virus. In May, CanSinoBIO received an emergency use listing (EUL) from the World Health Organization (WHO) for its recombinant Covid-19 shot, Convidecia.

Vaccine 264

Vaccine Vaccination Genetic Engineering Clinical Trials 264

BioSpace

JULY 27, 2021

breakthrough study has found that altering the genetic makeup of malaria-carrying mosquito species could be the key to stopping the spread of the malaria virus and finally eradicating the disease.

Genetic Engineering 95

Genetic Engineering Genetics Engineer 95

The Pharma Data

DECEMBER 14, 2020

FDA Approves Genetically Engineered Pigs for Food, Possible Medical Use. 14, 2020 — The first genetically engineered pigs for use as food or for potential future biomedical use — such as transplantation — in humans have been approved by the U.S. Professional. MONDAY, Dec. Food and Drug Administration.

Genetic Engineering 52

Genetic Engineering Engineer FDA Approval Genetics 52

BioSpace

AUGUST 31, 2020

Boston Pharmaceuticals licensed the drug candidate BOS-580, an injectable, genetically engineered variant of human FGF21.

Licensing 111

Licensing Licensing Genetic Engineering Engineer 111

Medical Xpress

JANUARY 5, 2023

A new study by Burke Neurological Institute (BNI), Weill Cornell Medicine, finds that activation of MAP2K signaling by genetic engineering or non-invasive repetitive transcranial magnetic stimulation (rTMS) promotes corticospinal tract (CST) axon sprouting and functional regeneration after spinal cord injury (SCI) in mice.

Genetic Engineering 119

Genetic Engineering Engineer Genetics Medicine 119

BioTech 365

DECEMBER 1, 2020

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Restoring eyesight with genetically engineered stem cells.Restoring eyesight with genetically engineered stem cells arlene.weintraub Mon, 11/30/2020 – 09:46 from FierceBiotech: Biotech [link].

Genetic Engineering 40

Genetic Engineering Engineer Genetics Research 40

Scienmag

DECEMBER 3, 2020

A new study has found that a novel T cell genetically engineered by University of Arizona Health Sciences researchers is able to target and attack pathogenic T cells that cause Type 1 diabetes, which could lead to new immunotherapy treatments.

Genetic Engineering 45

Genetic Engineering Engineer Genetics Bacteria 45

BioTech 365

OCTOBER 16, 2020

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Plant genetic engineering to fight hidden hunger.More than 2 billion people worldwide suffer from micronutrient malnutrition due to deficiencies in minerals and vitamins.

Genetic Engineering 40

Genetic Engineering Engineer Genetics Development 40

BioTech 365

AUGUST 24, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Genetically engineered good bacteria could aid in combating disease.Our bodies are home to several bacterial species that help us maintain our health and wellbeing.

Genetic Engineering 40

Genetic Engineering Bacteria Engineer Genetics 40