Drug Discovery World

JULY 29, 2022

A team led by researchers at HMS and the Broad has just accomplished the rare feat of connecting those dots for one important gut bacterium. You can change the bacterium and apply the same set of tests,” said Clardy. Such knowledge is essential for learning how to manipulate gut bacteria to treat or prevent illness.

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AuroBlog - Aurous Healthcare Clinical Trials blog

JANUARY 11, 2024

Zosurabalpin is highly effective against the bacterium carbapenem-resistant Acinetobacter baumannii (Crab), which is classified as a “priority 1” pathogen by the World Health Organization due to its growing presence in hospitals.

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Bacterium Bacteria Drugs Research 173

Bio Pharma Dive

JUNE 27, 2022

As hospitals have dealt with surging admissions and extended stays with COVID-19, staff and patients alike have still had to contend with another potentially deadly infection from a bacterium called Clostridioides difficile.

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Bacterium 246

Scienmag

JUNE 10, 2022

Washington, DC – June 10, 2022 – Globally, preterm birth complications are the leading cause of death for children under the age of 5. Not everyone faces the same risk, though: In the United States, roughly 10% of pregnancies lead to preterm birth, but for Black women, that likelihood is 14%. Recent studies suggest that the […].

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Bacterium 73

Scienmag

NOVEMBER 18, 2020

Credit: SDSU For a slow-growing microbe that multiplies infrequently, Mycobacterium tuberculosis, the pathogen that causes tuberculosis (TB) has long puzzled researchers as to how it develops resistance to antibiotics so quickly, in a matter of weeks to months.

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Medical Xpress

DECEMBER 20, 2022

A probiotic bacterium called Lacticaseibacillus rhamnosus HA-114 prevents neurodegeneration in the C. elegans worm, an animal model used to study amyotrophic lateral sclerosis (ALS).

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Bacterium Research 92

Scienmag

DECEMBER 7, 2020

Credit: Francesco Righetti Researchers at Karolinska Institutet in Sweden have come one step closer toward understanding why some people become seriously ill or die from a common bacterium that leaves most people unharmed.

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Bacterium Bacteria RNA Research 98

Scienmag

JUNE 20, 2021

By identifying one of the mechanisms regulating the virulence of Pseudomonas aeruginosa, a UNIGE team is proposing a new strategy to combat this bacterium, which is resistant to many common antibiotics Credit: © UNIGE Pseudomonas aeruginosa is an opportunistic pathogenic bacterium present in many ecological niches, such as plant roots, stagnant water (..)

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Bacteria Bacterium Regulation Medicine 81

Scienmag

DECEMBER 14, 2021

For the first time ever, scientists have been able to measure the speed of a bacterium that causes the incurable citrus greening disease. Citrus greening disease (also known as Huanglongbing) is the most devastating citrus disease in the world.

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Medical Xpress

APRIL 3, 2023

Yet, as many as two billion people are infected with Mycobaterium tuberculosis, the bacterium that causes tuberculosis, and are otherwise healthy and asymptomatic. More than 10 million people are sickened by tuberculosis (TB) globally each year, resulting in 1.5 million deaths.

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Bacterium Containment Scientist Vaccination 81

Medical Xpress

MARCH 27, 2023

diff infection caused by multiple strains of the bacterium, including those that cause serious illness. Each year, about 500,000 people in the U.S. deal with gastrointestinal infections from Clostridioides difficile (C. diff), and more than 20,000 die from these infections. diff infections in people.

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Bacterium Scientist Development Drugs 83

Scienmag

MARCH 4, 2022

Lyme disease is carried by black-legged ticks and infects people when they are bitten and transmit the bacterium Borrelia burgdorferi. Black-legged ticks are especially common in the northeastern United States, and people are exposed to the ticks usually during outdoor activities.

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Scienmag

MAY 12, 2022

of the University of Alabama at Birmingham have made what they call “a major step” in understanding how Mycobacterium tuberculosis acquires iron from its human host — a process essential for the pathogenesis of this bacterium. . – Lei Zhang, Ph.D., and Michael Niederweis, Ph.D.,

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Bacteria Bacterium Gene Medicine 84

Medical Xpress

MARCH 29, 2023

A large case-control study by international researchers at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan has found that people who carry certain genetic risk factors for gastric (stomach) cancer have a much greater risk if they have also been infected by the bacterium Helicobacter pylori.

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Genetics Bacterium Genome Genomics 81

Scienmag

SEPTEMBER 24, 2020

New form of insect-pathogenic bacterium extends the options for sustainable crop protection and biological pest control in agriculture Credit: ill./©: The bacterium Photorhabdus luminescens is one such beneficial organism.

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Bacterium 74

BioSpace

JUNE 27, 2022

Boehringer and BiomX intend to use the discovery platform to identify biomarkers for a pathogenic bacterium thought to be associated with IBD.

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Medical Xpress

MARCH 14, 2023

pylori) is an infectious bacterium that resides in the gastric mucosa and causes persistent gastric damage. Helicobacter pylori (H. pylori can cause chronic gastritis, peptic ulcers, and iron deficiency anemia. If left untreated, it can also lead to the development of stomach cancer. The World Health Organization classifies H.

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Bacterium Development Research 69

Scienmag

JUNE 28, 2021

In a new study, researchers have designed a miniaturized 3D-printed device to inactivate Pseudomonas aeruginosa, a common bacterium that causes the infection. Credit: Jungeun Won Middle ear infections, also known as otitis media, affect more than 80% of the children in the U.S.

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Bacterium Research Development Medicine 98

Medical Xpress

NOVEMBER 16, 2022

diff, is a bacterium that causes severe intestinal illness and, as its name suggests, can be difficult to study and treat. Clostridioides difficile, often referred to as C. difficile or C. Approximately 1 in 6 patients infected with C. difficile will be reinfected within two months. Yet scientists have not figured out why C.

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Drug Discovery World

AUGUST 7, 2023

Research published in Science shows that a naturally occurring bacterium discovered by GSK scientists – Delftia tsuruhatensis Tres Cantos 1 (TC1) – could be the basis for new anti-malarial interventions. The results suggest TC1 has potential to inhibit the development of all malaria parasites which affect humans (P. ovale and P. falciparum).

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Bacteria Bacterium Containment Scientist 52

Scienmag

JANUARY 19, 2021

Credit: University of Exeter Bioimaging Unit Scientists have discovered how bacteria commonly responsible for seafood-related stomach upsets can go dormant and then “wake up” Vibrio parahaemolyticus is a marine bacterium that can cause gastroenteritis in humans when eaten in raw or undercooked shellfish such as oysters and mussels.

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Bacteria Bacterium Scientist Medicine 98

Scienmag

NOVEMBER 24, 2021

The bacterium Xanthomonas campestris is the major cause of black rot disease, which works by retarding several light-mediated biological processes. Black rot disease in cabbages, radishes and related cruciferous crops may have disastrous consequences for the yield and production of marketable plants.

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Bacterium Production Marketing 80

Scienmag

DECEMBER 8, 2021

Scientists have demonstrated that modifying an enzyme produced by the bacterium that causes anthrax can protect mice from infection with the deadly disease.

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Bacterium Scientist Medicine 82

Scienmag

JUNE 24, 2021

Credit: UCSF Researchers at UCSF have found that extreme caloric restriction diets alter the microbiome in ways that could help with weight loss but might also result in an increased population of Clostridiodes difficile, a pathogenic bacterium that can lead to severe diarrhea and colitis.

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Bacterium Research Medicine 85

Scienmag

JUNE 10, 2022

Researchers have known for some time that maternal breast milk provides critical nutrients for newborns, and antibodies from mothers vaccinated against a specific disease-causing bacterium or virus can be transferred via breast milk to babies.

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Antibody Bacteria Bacterium Vaccination 72

Scienmag

APRIL 16, 2022

Two strains of the bacterium causing tuberculosis have only minor genetic differences but attack the lungs in completely different fashion, according to Rutgers researchers.

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Bacterium Genetics Research 73

Scienmag

NOVEMBER 19, 2020

Structural insights about a deadly bacterium’s toolbox point to ways to block it Credit: Maria Schumacher Lab, Duke Biochemistry DURHAM, N.C. – The bacterium that causes the tick-borne disease tularemia is a lean, mean infecting machine.

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Bacterium Genome Genomics Research 52

Scienmag

MARCH 2, 2021

— Envisioning an animal-free drug supply, scientists have — for the first time — reprogrammed a common bacterium to make a designer polysaccharide molecule used in pharmaceuticals and nutraceuticals. Process paves a road to safe, ethical, and fast drug manufacturing Credit: Rensselaer Polytechnic Institute TROY, N.Y.

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Bacteria Bacterium Drugs Scientist 86

Pharmaceutical Technology

MAY 18, 2023

An investigational orally delivered biologic drug, LMN-201 is a cocktail of four therapeutic proteins that act synergistically to neutralise the C difficile bacterium and the toxin. It is compatible with standard-of-care antibiotics.

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Bacterium Bacteria FDA Approval Trials 130

Scienmag

FEBRUARY 5, 2021

Treatment causes deadly bacterium to leak and die Credit: Hailing Jin/UCR New research affirms a unique peptide found in an Australian plant can destroy the No. 1 killer of citrus trees worldwide and help prevent infection. Huanglongbing, HLB, or citrus greening has multiple names, but one ultimate result: bitter and worthless citrus fruits.

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Bacterium Research Production Gene 92

Scienmag

OCTOBER 15, 2020

Credit: (Image: Chair of Molecular Infection Biology II / University of Wuerzburg / SCIGRAPHIX) More than half of the world’s population carries the bacterium Helicobacter pylori in their stomach mucosa.

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RNA Bacterium Development Genetics 93

Scienmag

MARCH 30, 2022

noa scientists highlights the potential for using oceanographic sensors to make accurate predictions of Vibrio vulnificus, an infectious bacterium, in the Ala Wai Canal in Waikiki, Hawai‘i. Recently published research led by University of Hawai‘i (UH) at M?noa

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Bacteria Bacterium Scientist Research 59

Scienmag

JULY 20, 2021

Scientists discover gliding machinery for Mycoplasma mobile to be a new structure that could share ancestry with ATP synthase Credit: Yuya Sasajima (Osaka City University) For more than 20 years, Makoto Miyata from Osaka City University has been studying the gliding motility of the parasitic bacterium Mycoplasma mobile (M.

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Bacterium Scientist 71

Scienmag

MARCH 22, 2022

The disease is caused by a bacterium, Mycobacterium […].

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Bacterium Scientist Drugs Medicine 88

Scienmag

JUNE 23, 2021

Bacterium associated with antibiotic-induced colitis plays a role in weight control Credit: © CDC | Janice Carr Researchers from Charité – Universitätsmedizin Berlin and the University of California in San Francisco were able to show for the first time that a very low calorie diet significantly alters the composition of the microbiota present (..)

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Bacterium Research Medicine 68

Scienmag

MAY 18, 2021

Tuberculosis, a disease caused by the bacterium Mycobacterium tuberculosis (Mtb), is typically the leading infectious cause of death globally, killing 1.2 million […].

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Bacterium Research Development Medicine 72

Scienmag

JULY 7, 2021

Researchers have produced vaccine-like immune responses to a dangerous bacterium by colonizing 26 healthy volunteers with a related, but harmless, commensal bacterial species.

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Bacteria Bacterium Vaccination Vaccine 75