Medical Xpress

MAY 15, 2023

Fresh insights into the spread of damaging proteins that build up in the brains of people with Alzheimer's disease could hold the key to stopping the condition from progressing, a study says.

Protein 138

Protein 138

Bio Pharma Dive

AUGUST 2, 2022

It’s the second deal in as many years between AbbVie and Sosei Heptares, which together have been trying to develop drugs that target so-called G protein-coupled receptors.

Protein 273

Protein Drugs Development 273

Pharmaceutical Technology

MARCH 21, 2023

Gilead Sciences has exercised its option to exclusively license the investigational targeted protein degrader development candidate, NX‑0479, from clinical-stage biopharmaceutical company Nurix Therapeutics. GS-6791 is the first development candidate from the previous collaboration between Gilead Sciences and Nurix in 2019.

Protein 130

Protein Licensing Licensing Development 130

Pharmaceutical Technology

FEBRUARY 16, 2023

Aqilion and Merck have entered an exclusive licence and strategic research partnership for the discovery, development and commercialisation of the transforming growth factor-β-activated kinase 1 (TAK1) protein-small molecule inhibitors.

Protein 147

Protein Development Drugs Trials 147

Bio Pharma Dive

DECEMBER 6, 2022

Entact Bio aims to develop medicines that can enhance helpful proteins, rather than block harmful ones, a twist on the usual drugmaking playbook.

Protein 209

Protein Medicine Development 209

pharmaphorum

AUGUST 5, 2021

Protein-protein interactions (PPIs) are becoming increasingly relevant in the pathology of many diseases, including cancer. PPIs are an integral part of the physiology of living organisms, as complexes which control biological pathways mediated by proteins. These regions are critical for optimal interactions between proteins.

Protein 126

Protein Gene Bioassay Clinical Research 126

Bio Pharma Dive

JULY 28, 2022

Vicinitas and its protein-stabilizing research have attracted $65 million from a group of investors that includes a16z, Deerfield and GV.

Protein 261

Protein Research 261

Bio Pharma Dive

JANUARY 27, 2022

Backed by some of biotech's most powerful investors, Septerna is looking to usher in the next chapter of medicines that act on G protein-coupled receptors.

Protein 318

Protein Medicine Drugs 318

Pharmaceutical Technology

APRIL 6, 2023

Biotheryx and Incyte have signed an agreement for identifying and developing targeted protein degraders for historically undruggable oncology targets. Incyte will pay a $7m technology access fee to Biotheryx for the initial target and potential research, and development funding of up to an additional $6m for costs related to the partnership.

Protein 130

Protein Development Sales Research 130

Drug Discovery World

MAY 4, 2023

Adaptyv Bio, a Swiss/US technology company that develops infrastructure and tools for protein designers to engineer better proteins, has built a protein engineering foundry that it says will “pave the way” for protein designers to develop new medicines, novel enzymes and sustainable materials.

Protein 52

Protein Engineer Life Science Medicine 52

Bio Pharma Dive

DECEMBER 16, 2022

The pharma will pay Sosei $37 million upfront to discover new candidates for diabetes and metabolic diseases that target G protein-coupled receptors.

Protein 157

Protein Drugs Development 157

Drug Discovery World

MAY 18, 2023

Read this guide to learn about common roadblocks, technologies to overcome them, and how to ensure you’re on the right track to building an efficient protein degrader.

Protein 52

Protein Drugs Development 52

Medical Xpress

MAY 16, 2023

Researchers at the University Medical Center Hamburg-Eppendorf have demonstrated cross-reactive immune responses to another SARS-CoV-2 protein besides the spike protein.

Protein 98

Protein RNA Immune Response Research 98

Drug Discovery World

MAY 18, 2023

Read this guide to learn about common roadblocks, technologies to overcome them, and how to ensure you’re on the right track to building an efficient protein degrader. The post Build effective protein degraders – answer these four questions appeared first on Drug Discovery World (DDW).

Protein 52

Protein Drugs Development 52

Pharmaceutical Technology

SEPTEMBER 14, 2022

API peptides and proteins-based drugs have gained much attention in the past decade. Discover the top API protein and peptide companies in contract marketing. Technologies in the delivery of peptides and proteins. They are promising therapeutics for the treatment of a variety of metabolic and oncological disorders.

Protein 130

Protein Reagent Marketing Drugs 130

Medical Xpress

FEBRUARY 16, 2023

An adenovirus serotype 26 respiratory syncytial virus (RSV) vector encoding a prefusion F (preF) protein (Ad26.RSV.preF) RSV.preF) in combination with RSV preF protein is immunogenic and prevents RSV-mediated lower respiratory tract disease in older adults, according to a study published in the Feb.

Protein 97

Protein Vaccination Vaccine Medicine 97

XTalks

APRIL 26, 2022

California-based startup Air Protein developed an alt meat called Air Meat, which is made using microbes that turn recycled carbon dioxide (CO2) into protein. So, how does the company make alt protein out of thin air? After that, in a process like beer fermentation, the protein is turned into a flour-like substance.

Protein 94

Protein Scientist Branding Production 94

Medical Xpress

MARCH 29, 2023

Fungi-derived mycoprotein is just as effective at supporting muscle building during resistance training as animal protein, according to the findings of a new study from the University of Exeter.

Protein 75

Protein 75

Medical Xpress

MARCH 8, 2023

A study published in the Journal of Orthopaedic Research has identified a bone matrix protein called Secreted phosphoprotein 24 kD (Spp24) that may help to treat osteosarcoma, the most common type of bone cancer.

Protein 96

Protein Research 96

pharmaphorum

MAY 31, 2023

6th Targeted Protein Degradation Summit Mike.Hammerton Wed, 05/31/2023 - 10:10 Bookmark this

Protein 52

Protein 52

Medical Xpress

APRIL 20, 2023

A team with the participation of researchers from the Institute for Advanced Chemistry of Catalonia (IQAC) of the Spanish National Research Council (CSIC) has revealed the structure of the protein responsible for Huntington's disease, a severe neurodegenerative pathology characterized by the progressive disorder of movement and cognitive function. (..)

Protein 98

Protein Research 98

Medical Xpress

APRIL 19, 2023

In research published in The FASEB Journal, scientists have discovered that a molecule called Yes-associated protein (YAP) plays a key role in the development of liver scarring, or fibrosis, by influencing the behavior of premature cells called liver progenitor cells.

Protein 97

Protein Scientist Research Development 97

The Pharma Data

OCTOBER 17, 2022

Protein IDs, medicine campaigners, show pledge for COVID wisdom A largely innovative system using the rearmost technology has generated a comprehensive list of SARS- CoV- 2 viral and mortal proteins that interact with each other, with one similar commerce showing the contagion directly impacting proteins that regulate the mortal vulnerable system.

Protein 98

Protein Drugs Medicine Gene Expression 98

Medical Xpress

FEBRUARY 17, 2023

Researchers at the National Institutes of Health and their colleagues have found that a toxic protein made by the body called DUX4 may be the cause of two very different rare genetic disorders.

Protein 98

Protein Genetics Research 98

Medical Xpress

FEBRUARY 22, 2023

Medicines that are based on mRNAs and proteins—particularly vaccines and antibodies—are time-intensive and costly to make. The challenge is in producing the necessary mRNAs and proteins in large enough amounts at low cost.

Protein 75

Protein Medicine Antibody Vaccination 75

Scienmag

JANUARY 6, 2022

Protein assembly is essential for the formation of ordered biological structures, but imagine engineering one! This is exactly what researchers at Tokyo Tech have now accomplished with protein needles.

Protein 79

Protein Regulation Engineer Research 79

XTalks

MARCH 31, 2023

By growing high quality crystal structures of protein-based therapeutics under microgravity, researchers can gain better insights into their complex structures and stability. The proteins will be analyzed back on Earth using techniques such as X-ray diffraction and compared with crystals from the same biologics grown on Earth.

Protein 94

Protein Research Drugs Pharma Companies 94

Medical Xpress

APRIL 26, 2023

Researchers at Nagoya University in Japan have discovered a receptor, sigma-1 receptor, and a protein, ATAD3A, that are associated with Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease. Since there are drugs that specifically target the receptor, their findings suggest a new therapeutic strategy.

Protein 93

Protein Drugs Research 93

Drug Discovery World

MARCH 30, 2023

Salipro Biotech, in collaboration with AstraZeneca, has published data from a study which describes a novel method to directly extract membrane proteins from cells into lipid Salipro nanoparticles, enabling structure-function analysis using surface plasmon resonance (SPR) and cryo-electron microscopy (cryo-EM) for challenging drug targets.

Protein 52

Protein Drugs Scientist Engineer 52

Drug Discovery World

MAY 18, 2023

Scientists in Japan have used a novel technique to identify a protein complex degraded by autophagy that has a possible role in liver cancer. p62 protein forms a membrane-less cytosolic organelle called p62 body and helps in the selective removal of toxic cellular waste through autophagy.

Protein 52

Protein Medicine Scientist Drugs 52

STAT News

DECEMBER 2, 2022

A Somerville startup and an academic lab in Seattle say they have developed a way to use artificial intelligence to design proteins that don’t exist in nature. Proteins help people move, digest food, and fight infections — to name a few of their numerous functions. And for some scientists, nature is too limiting.

Protein 111

Protein Scientist Drugs Development 111

Medical Xpress

OCTOBER 4, 2022

New research from the University of Cincinnati bolsters a hypothesis that Alzheimer's disease is caused by a decline in levels of a specific protein, contrary to a prevailing theory that has been recently called into question.

Protein 131

Protein Research 131

Medical Xpress

APRIL 12, 2023

A technique that identifies the build-up of abnormal protein deposits linked to Parkinson's disease could aid in early detection and play a key role in the disease's clinical diagnosis and characterization, according to research published in The Lancet Neurology journal.

Protein 98

Protein Research 98

Medical Xpress

NOVEMBER 8, 2022

Researchers at the University of Maryland School of Medicine's (UMSOM) Center for Precision Disease Modeling identified how a specific protein in SARS-CoV-2, the virus responsible for COVID-19, damages heart tissue. They then used a drug to reverse the toxic effects of that protein on the heart.

Protein 98

Protein Medicine Drugs Research 98

Medical Xpress

MARCH 27, 2023

In a new study, researchers examined how a country's number of published 3D protein structures for coronaviruses, including the one responsible for COVID-19, correlated with its economic output and population.

Protein 96

Protein Research 96

Medical Xpress

MARCH 2, 2023

Proteins, long polymers comprised of smaller constituents known as amino acids, play a crucial role in the functioning of the human body.

Protein 105

Protein Regulation 105

Medical Xpress

MARCH 28, 2023

The fast motor kinetics of prestin, a protein found in the inner ear, is essential for hearing high-frequency sounds, according to a Northwestern Medicine study published in the Proceedings of the National Academy of Sciences.

Protein 81

Protein Medicine Research 81