Lilly puts more money into protein degradation
Bio Pharma Dive
AUGUST 25, 2021
The pharma has struck its second research pact focused on drugs that break down harmful proteins in as many years, this time with California biotech Lycia Therapeutics
Protein Related Topics 
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Evaluating methods targeting Protein-Protein Interactions
Pharma Phorum
AUGUST 5, 2021
Protein-protein interactions (PPIs) are becoming increasingly relevant in the pathology of many diseases, including cancer. PPIs are an integral part of the physiology of living organisms, as complexes which control biological pathways mediated by proteins.
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Feinstein Institutes researchers discover new protein for sepsis treatment
Pharmaceutical Technology
FEBRUARY 6, 2023
Researchers at the Feinstein Institutes for Medical Research have discovered a new protein that can be a potential therapeutic target for lethal sepsis. The post Feinstein Institutes researchers discover new protein for sepsis treatment appeared first on Pharmaceutical Technology.
With $81M, Entact Bio takes a new approach to fixing helpful proteins
Bio Pharma Dive
DECEMBER 6, 2022
Entact Bio aims to develop medicines that can enhance helpful proteins, rather than block harmful ones, a twist on the usual drugmaking playbook
Gladstone and UCSF scientists discover BET protein role in Covid-19
Pharmaceutical Technology
JULY 20, 2022
Researchers at Gladstone Institutes and UC San Francisco (UCSF) have discovered in a study that bromodomain and extraterminal (BET) proteins are vital for the body to fight Covid-19 infection. . These findings indicated that BET proteins have a vital role in enabling and combating Covid-19.
Protein folding in times of oxygen deficiency
Scienmag
JULY 12, 2022
Proteins often consist of hundreds or thousands of individual parts, the amino acids. However, protein molecules would not be able to fulfill their task as a long filament flapping back and forth. Chemistry AND Physics deficiency folding oxygen protein times
Decoding protein assembly dynamics with artificial protein needles
Scienmag
JANUARY 6, 2022
Protein assembly is essential for the formation of ordered biological structures, but imagine engineering one! This is exactly what researchers at Tokyo Tech have now accomplished with protein needles. Biology Artificial assembly Decoding dynamics needles protein
Artificial muscles made of proteins
Scienmag
JANUARY 28, 2022
Stefan Schiller and Dr. Matthias Huber from the University of Freiburg’s livMatS Cluster of Excellence have succeeded in developing a muscle solely on the basis of natural proteins. Latest News Artificial muscles proteins
AbbVie, targeting a well-known protein family, expands a partnership into neuroscience
Bio Pharma Dive
AUGUST 2, 2022
It’s the second deal in as many years between AbbVie and Sosei Heptares, which together have been trying to develop drugs that target so-called G protein-coupled receptors
Deep learning reveals how proteins interact
Scienmag
NOVEMBER 22, 2021
Scientist are now combining recent advances in evolutionary analysis and deep learning to build three-dimensional models of how most proteins in eukaryotes interact. Biology deep interact learning proteins reveals
Protein supplement helps control Type 2 diabetes
Scienmag
MAY 26, 2022
Drinking a small amount of whey protein before meals has been shown to help people with type 2 diabetes control their blood sugars. Social & Behavioral Science control Diabetes helps protein supplement type
Lilly partners with Sosei to develop drugs aimed at a key family of proteins
Bio Pharma Dive
DECEMBER 16, 2022
The pharma will pay Sosei $37 million upfront to discover new candidates for diabetes and metabolic diseases that target G protein-coupled receptors
Identifying individual proteins using nanopores and supercomputers
Scienmag
NOVEMBER 10, 2021
The amount and types of proteins our cells produce tell us important details about our health and how our bodies work. But the methods we have of identifying and quantifying individual proteins are inadequate to the task.
How can a protein help us remember?
Scienmag
DECEMBER 11, 2021
Studying fruit flies, they found that the Apterous (Ap) protein plays a crucial double role in retaining memories. Biology protein rememberTokyo, Japan – Researchers from Tokyo Metropolitan University have gained insights into the biochemistry of long-term memory.
Balancing protein in your diet could improve water quality
Scienmag
JULY 7, 2022
Balancing how much protein you eat with the amount your body needs could reduce nitrogen releases to aquatic systems in the U.S. Credit: Courtesy Maya Almaraz Balancing how much protein you eat with […]. Technology and Engineering Balancing diet improve protein quality water
CDC backs Novavax's protein-based vaccine for COVID-19
Bio Pharma Dive
JULY 20, 2022
Health officials argue a new type of shot could help to persuade unvaccinated people, although some surveys suggest that might not be the case
Touting a new way to drug an all-important family of proteins, a startup launches with $100M
Bio Pharma Dive
JANUARY 27, 2022
Backed by some of biotech's most powerful investors, Septerna is looking to usher in the next chapter of medicines that act on G protein-coupled receptors
Unexpected protein could play role in common brain disorder
Scienmag
APRIL 19, 2022
Scientists have known for years that amyloid fibrils — fibrous, ropelike structures formed by closely linked protein molecules — are present in the brains of patients with Alzheimer’s and Parkinson’s diseases and likely play a role in the progression of these disorders.
Without ‘work-life balance,’ this protein may promote disease
Scienmag
MAY 19, 2022
COLUMBUS, Ohio – A family of proteins that have a role in ensuring many types of cells move and maintain their shape may promote disease when they act like workaholics and disrupt the cellular environment, new research suggests. Latest News balance Disease promote protein worklife
Gene important in soybean protein content found after 30-year search
Scienmag
FEBRUARY 10, 2022
Soybeans outmatch all other legumes as the protein powerhouses of the plant kingdom, providing a key protein source for humans and livestock around the world. Social & Behavioral Science 30year Content gene important protein search SoybeanURBANA, Ill.
Newly discovered protein in fungus bypasses plant defenses
Scienmag
APRIL 25, 2022
April 25, 2022—A protein that allows the fungus which causes white mold stem rot in more than 600 plant species to overcome plant defenses has been identified by a team of U.S. April 25, 2022—A protein that allows […]. Pullman, Wash.,
Oral Protein / Peptide-based Drugs: Addressing Key Unmet Needs Across Disease Indications
Roots Analysis
MARCH 2, 2022
Orally administrable protein / peptide-based therapeutics offer several advantages including, effective treatment of numerous clinical conditions and degenerative disorders. Pipeline Overview of Oral Peptide and Protein-based Therapeutics. Oral Protein / Peptide-based Drugs.
Disarming a blood-clotting protein prevents gum disease in mice
Scienmag
DECEMBER 23, 2021
Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, according to research led by scientists at the National Institute of Dental and Craniofacial Research (NIDCR), part of the National Institutes of Health.
New Machine Learning maps the potentials of proteins
Scienmag
MAY 4, 2022
The biotech industry is constantly searching for the perfect mutation, where properties from different proteins are synthetically combined to achieve a desired effect. Social & Behavioral Science learning machine maps potentials proteins
Uncovering warped protein interactions in cancer
Scienmag
MAY 4, 2022
Scientists at Emory have revealed widespread distortions of a cell’s protein interaction machinery resulting from cancer-causing mutations. One reason why a mutation is tumorigenic is the altered network of protein-protein […]. Latest News cancer interactions protein Uncovering warpedThey developed a process resembling ground-penetrating radar, for its ability to map the hidden landscape of anticancer drug opportunities. The results are published in Cell.
Protein protects brain cells most impacted by glaucoma
Scienmag
MARCH 1, 2022
March 1, 2022) — A ubiquitous protein called sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of the neurons most impacted by glaucoma, scientists report. March 1, 2022) — A ubiquitous protein called sigma 1 receptor, […].
BETting on COVID-19: Study probes role of BET proteins in coronavirus infection
Scienmag
JULY 19, 2022
SAN FRANCISCO, CA—A while ago, some researchers had suggested that blocking a set of proteins, known as bromodomain and extraterminal (BET) proteins, might be a way to fight COVID-19. Biology BET betting coronavirus COVID19 infection probes proteins role study
Protein structure offers clues to drug-resistance mechanism
Scienmag
FEBRUARY 18, 2022
CAMBRIDGE, MA — MIT chemists have discovered the structure of a protein that can pump toxic molecules out of bacterial cells. Proteins similar to this one, which is found in E. Medicine & Health clues drugresistance mechanism offers protein structure
Viral proteins join forces to lower plants’ defense ‘shields’
Scienmag
JANUARY 25, 2022
New research, led by Washington State University scientists, into how viral proteins interact and can be disabled holds promise to help plants defend themselves against viruses—and ultimately prevent crop losses. Latest News defense forces join plants proteins shields viral
AI-designed protein awakens silenced genes, one by one
Scienmag
MARCH 4, 2022
By combining CRISPR technology with a protein designed with artificial intelligence, it is possible to awaken individual dormant genes by disabling the chemical “off switches” that silence them. Biology AIdesigned awakens Genes protein silenced
Air Protein: The Alt Meat Startup Making Plant-Based Protein Out of Thin Air
XTalks
APRIL 26, 2022
California-based startup Air Protein developed an alt meat called Air Meat, which is made using microbes that turn recycled carbon dioxide (CO2) into protein. So, how does the company make alt protein out of thin air?
Study details changes in omicron’s spike protein
Scienmag
JANUARY 25, 2022
An international team of scientists has determined the precise structural changes in the spike protein of the omicron variant. Biology details omicrons protein Spike study
Advanced microscopes help scientists understand how cells break down proteins
Scienmag
NOVEMBER 17, 2021
Proteins are the building blocks of all living things. A vast amount research takes place on how these proteins are made and what they do, from enzymes that carry out chemical reactions to messengers that transmit signals between cells.
Imaging solves mystery of how large HIV protein functions to form infectious virus
Scienmag
JULY 6, 2022
Now, a team of scientists from the Salk Institute and Rutgers University have for the first time determined the molecular structure of HIV Pol, a protein that plays […]. Medicine & Health form functions HIV imaging infectious large mystery protein solves virus
Bioproduction Breakthrough: New method for developing Pichia pastoris yeast strains with high productivity of useful proteins
Scienmag
JULY 7, 2022
A collaboration including researchers from Kobe University, University of Tokyo and Tohoku University has successfully identified and disrupted genes in the yeast Pichia pastoris (1) in order to increase its secretory production of useful proteins (2).
New insights of how the HIV-1 assembles and incorporates the Env protein
Scienmag
JUNE 21, 2022
Assembly of HIV-1, which causes AIDS, takes place on the inner plasma membrane leaflet of infected cells, a geometric building process that creates hexamers out of trimers of the viral Gag protein, as guided by Gag’s N-terminal matrix domain. BIRMINGHAM, Ala.
Suffering from psoriasis? Blame this trio of proteins
Scienmag
NOVEMBER 19, 2021
Medicine & Health Blame proteins psoriasis Suffering trioLA JOLLA—About 7.5 million Americans suffer from psoriasis, an autoimmune disease that shows up as patches of red, inflamed skin and painful, scaly rashes.
Intracellular temperature sensors: Protein complex exhibits temperature-sensitive activity
Scienmag
NOVEMBER 9, 2021
Osaka, Japan – One degree (Celsius) can make a difference: a team of investigators led by Osaka University has demonstrated regulation of a critical protein complex that occurs only at physiological temperature.
AF2Complex: Researchers leverage deep learning to predict physical interactions of protein complexes
Scienmag
APRIL 18, 2022
From the muscle fibers that move us to the enzymes that replicate our DNA, proteins are the molecular machinery that makes life possible. Protein function […]. Chemistry AND Physics AF2Complex complexes deep interactions learning leverage Physical predict protein researchers
Deep-learning algorithm aims to accelerate protein engineering
Scienmag
OCTOBER 7, 2021
Machine learning algorithms assist in protein engineering by reducing the experimental burden of methods such as directed evolution, which involves multiple rounds of mutagenesis and high-throughput screening.
Genetically modified proteins convert carbon nanotube to programmable optoelectronic device
Scienmag
MARCH 30, 2022
Russian researchers and their international collaborators have developed a full-function bioelectronic photocell using one molecule of a fluorescent protein attached to a carbon nanotube. When exposed to light, the system can change its electronic properties and operate either as a spotlight or memory cell depending on how the protein is attached to the tube. Technology and Engineering carbon convert device genetically modified Nanotube optoelectronic Programmable proteins
Stress protein in fibroblasts may be a good target for future cancer drugs, Penn study finds
Scienmag
JUNE 10, 2022
Cancer cancer Drugs fibroblasts finds future good Penn protein stress study target
U of T researchers find trove of proteins that may influence cystic fibrosis
Scienmag
FEBRUARY 14, 2022
Researchers at the University of Toronto have identified hundreds of new proteins that could play a role in cystic fibrosis, and which may shed light on why some patients respond better than others to current therapies.
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