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Gain Therapeutics has priced its initial public offering, raising more than $40 million for its computational drug discovery platform and pipeline of drugs for diseases associated with protein misfolding. . The post Protein misfolding specialist Gain nets $40m from IPO appeared first on. MORE
Study reveals mechanism used to regulate chaperone proteins, which guide other proteins into proper shapes Credit: UT Southwestern Medical Center DALLAS – Feb. MORE
Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Inhibiting pancreatic cancer by exploiting a protein loophole.Inhibiting pancreatic cancer by exploiting a protein loophole aliu Wed, 03/03/2021 – 05:24 from FierceBiotech: Biotech [link]. MORE
Credit: Proceedings of the National Academy of Sciences Ribosomes are the complexes of ribonucleoproteins at the heart of protein synthesis in cells. MORE
One such fusion beverage is high-protein iced tea – a functional, refreshing beverage that has the potential to be the next big beverage trend. As an ingredient, whey protein comes with some challenges. MORE
Credit: Surajit Chatterjee To better understand how RNA in bacteria gives rise to protein–and along the way, target these processes in the design of new antibiotics–researchers are turning their attention to the unique way this process happens in bacteria. MORE
Credit: University of Leeds A visualisation made from nearly 100,000 electron microscope images has revealed the ingenious way a protein involved in muscle activity shuts itself down to conserve energy. MORE
Credit: POSTECH Blood vessels deliver nutrients and oxygen to each organ in our body. They are difficult to completely restore to their original conditions once damaged by myocardial infarction or severe ischemic diseases. MORE
Credit: University of Leeds The UK’s leading scientific academy – the Royal Society – has awarded one of its most prestigious research professorships to an academic at the University of Leeds, to develop new ways of ‘seeing the unseen’ – the way that proteins interact to shape or to destroy memories. MORE
NanoString Launches GeoMx DSP Protein Assays for Next Generation Sequencing NanoString Launches GeoMx DSP Protein Assays for Next Generation Sequencing GeoMx Digital Spatial Profiler (DSP) Now Enables Multi-Analyte Spatial Analysis Using Both NGS and nCounter Read-outs SEATTLE–(BUSINESS WIRE)–NanoString Technologies, Inc. MORE
Proteins engineered to form honeycomb structures can block uptake of receptors from the surface of cells Credit: Ian Haydon, UW Medicine Institute for Protein Design A new class of protein material that interacts with living cells without being absorbed by them can influence cell signaling, a new study shows. MORE
and Alessandra Villa – alessandra.villa@philogen.com Oncotarget recently published “A novel format for recombinant antibody-interleukin-2 fusion proteins […]. MORE
The study, published in Nature Communications, shows how bacterial protein ‘cages’ can be reprogrammed as nanoscale bioreactors for hydrogen production. MORE
24, 2021 — Postmenopausal women who ate high levels of plant protein had lower risks of premature death, cardiovascular disease and dementia-related death compared with women who ate less plant proteins, according to new research published today in the Journal of the American Heart Association, an […]. Journal of the American Heart Association report DALLAS, Feb. MORE
New technology enables ultrafast identification of COVID-19 biomarkers Credit: Photo: Arne Sattler/Charité Researchers from Charité – Universitätsmedizin Berlin and the Francis Crick Institute have developed a mass spectrometry-based technique capable of measuring samples containing thousands of proteins within just a few minutes. MORE
Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Programming proteins to turn cells into molecular computers.A new method of breaking and fixing proteins could speed the development of sophisticated computer-like circuits in cells that will … Continue reading → #news MORE
Credit: WEHI, Australia The latest animation technology has revealed the molecular detail of how our bodies are protected from cancer by a key ‘tumour suppressor’ protein called p53. The new WEHI-TV animation visualises discoveries from more than 40 years of research to explain how the tumour suppressor protein p53 normally prevents cancer-causing changes in cells. […]. MORE
For the first time, a UNIGE team has been able to follow precisely the path taken by a protein within the cell, paving the way for the study of the transport and distribution network of vital elements necessary for its survival. MORE
Study shines light on how tau aggregates promote neurodegeneration Look deep inside the brain of someone with Alzheimer’s disease, most forms of dementia or the concussion-related syndrome known as chronic traumatic encephalopathy (CTE) and you’ll find a common suspected culprit: stringy, hairball-like tangles of a protein called tau. MORE
Louis and of immunology and internal medicine at the School of Medicine, and his team are experts in footprinting proteins — that is, using advanced methods for investigating the structure and interactions of proteins within larger molecules. Michael Gross, professor of chemistry in Arts & Sciences at Washington University in St. MORE
— Scientists at the University of Wisconsin-Madison have developed a way to use a cell’s own recycling machinery to destroy disease-causing proteins, a technology that could produce entirely new kinds of drugs. Some cancers, for instance, are associated with abnormal proteins or an excess of normally harmless proteins. MADISON, Wis. MORE
Credit: FEFU press office Scientists from the Pacific Quantum Center of Far Eastern Federal University (FEFU) figured out how the AFV3-109 protein with slipknot structure folds and unfolds depending on temperature. MORE
Credit: Pixabay/Yen Strandqvist, Chalmers University of Technology Artificial Intelligence is now capable of generating novel, functionally active proteins, thanks to recently published work by researchers from Chalmers University of Technology, Sweden. MORE
How tightly cells clump together, known as cell adhesion, appears to be enabled by a protein better known for its role in the immune system. MORE
Scientists from Japan employ a novel two-step method of labeling neurotransmitter receptor proteins to track their localization efficiently Credit: Shigeki Kiyonaka The neurons in our nervous system “talk” to each other by sending and receiving chemical messages called neurotransmitters. MORE
Blanc, Michael Gecht, Roberto Covino and Gerhard Hummer A new, detailed model of the surface of the SARS-CoV-2 spike protein reveals previously unknown vulnerabilities that could inform development of vaccines. MORE
Credit: The Protein Society The Protein Society, the premier international society dedicated to supporting protein research, announces the winners of the 2021 Protein Society Awards, which will be conferred at the 35th Anniversary Symposium (virtual), July 7 – 14, 2021. MORE
– Researchers in the Oregon State University College of Science have taken a key step toward new drugs and vaccines for combating COVID-19 with a deep dive into one protein’s interactions with SARS-CoV-2 genetic material. Credit: OSU College of Science CORVALLIS, Ore. MORE
February 23, 2021) – The Gates Biomanufacturing Facility (GBF) has completed the manufacturing and release of a protein-based biologic under Good Manufacturing Practice for Phase 1 Investigational Drugs for first-in-human clinical trials. Manufacturing of this investigational, protein product demonstrates the GBF’s capacity to support both academic endeavors from Colorado’s university research centers and […]. Aurora, Colo. MORE
Investigations of a cellular protein have uncovered a possible link with schizophrenia Credit: Mindy Takamiya/Kyoto University iCeMS Scientists have suspected mutations in a cellular cholesterol transport protein are associated with psychiatric disorders, but have found it difficult to prove this and to pinpoint how it happens. MORE
– New research led by scientists at Washington State University has found that a protein known as GBP5 appears to play a key role in suppressing inflammation in rheumatoid arthritis, a potentially debilitating disease in which the immune system mistakenly attacks the […]. MORE
Credit: Graphic by Shireen Dooling Often considered the workhorses of the body, proteins are among the most important biomolecules critical to life processes. MORE
Credit: OIST A protein that’s common throughout the body plays a key role in regulating glucose levels, says new research conducted in the Cell Signal Unit at the Okinawa Institute of Science and Technology Graduate University (OIST) and Riken Center of Integrative Medical Sciences. MORE
An alliance with BeyondSpring spinout Seed Therapeutics makes Eli Lilly the latest pharma company to dive into the fast-emerging drug research field MORE
With protein misfolding and aggregation prevalent in neurodegeneration, cancer, metabolic and ophthalmic diseases, the unmet clinical need presents huge opportunity to accelerate the discovery and translation of novel therapeutics to transform patient outcomes. MORE
Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Supersaturation: The barrier between protein folding and misfolding.Correct, or native, protein folding is essential for correct protein function. Protein misfolding can lead to the formation of amyloid … Continue reading → #news MORE
Oak Brook, IL – The April edition of SLAS Discovery is a special issue on advances in protein degradation curated by guest editors M. Targeted protein degradation has generated interest within the drug discovery arena due to the inhibition of one particular function of a protein not […]. Paola Castaldi, Ph.D., and Stewart L. Fisher, Ph.D. MORE
Researchers from Aarhus University have developed a tool, ODiNPred, for prediction of the degree of structural order and disorder in proteins, by using machine learning together with experimental NMR data for hundreds of proteins. MORE
Oikos has started the new year by introducing new protein-filled products to their dairy line. Their products provide a good source of protein, calcium and come in two snackable forms that boast up to 25 grams of protein. The protein ingredients market size was $38.02 MORE
Protein Related Topics Pharma Phorum
SEPTEMBER 2, 2020
With protein misfolding and aggregation prevalent in neurodegeneration, cancer, metabolic and ophthalmic diseases, the unmet clinical need presents huge opportunity to accelerate the discovery and translation of novel therapeutics to transform patient outcomes.
Scienmag
MARCH 25, 2021
New technology enables ultrafast identification of COVID-19 biomarkers Credit: Photo: Arne Sattler/Charité Researchers from Charité – Universitätsmedizin Berlin and the Francis Crick Institute have developed a mass spectrometry-based technique capable of measuring samples containing thousands of proteins within just a few minutes.
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XTalks
OCTOBER 27, 2020
One such fusion beverage is high-protein iced tea – a functional, refreshing beverage that has the potential to be the next big beverage trend. As an ingredient, whey protein comes with some challenges.
Pharma Phorum
MARCH 19, 2021
Gain Therapeutics has priced its initial public offering, raising more than $40 million for its computational drug discovery platform and pipeline of drugs for diseases associated with protein misfolding. . The post Protein misfolding specialist Gain nets $40m from IPO appeared first on.
Scienmag
FEBRUARY 11, 2021
Study reveals mechanism used to regulate chaperone proteins, which guide other proteins into proper shapes Credit: UT Southwestern Medical Center DALLAS – Feb.
XTalks
JANUARY 21, 2021
Oikos has started the new year by introducing new protein-filled products to their dairy line. Their products provide a good source of protein, calcium and come in two snackable forms that boast up to 25 grams of protein. The protein ingredients market size was $38.02
Scienmag
APRIL 8, 2021
Credit: © Terence Strick The Mfd protein repairs bacterial DNA, but can also, to scientists’ surprise, promote mutation. Using a specialized protein, […].
Scienmag
MARCH 29, 2021
Credit: The Protein Society The Protein Society, the premier international society dedicated to supporting protein research, announces the winners of the 2021 Protein Society Awards, which will be conferred at the 35th Anniversary Symposium (virtual), July 7 – 14, 2021.
Scienmag
JANUARY 13, 2021
Credit: FEFU press office Scientists from the Pacific Quantum Center of Far Eastern Federal University (FEFU) figured out how the AFV3-109 protein with slipknot structure folds and unfolds depending on temperature.
Scienmag
MARCH 29, 2021
– New research led by scientists at Washington State University has found that a protein known as GBP5 appears to play a key role in suppressing inflammation in rheumatoid arthritis, a potentially debilitating disease in which the immune system mistakenly attacks the […].
Scienmag
JANUARY 6, 2021
Proteins engineered to form honeycomb structures can block uptake of receptors from the surface of cells Credit: Ian Haydon, UW Medicine Institute for Protein Design A new class of protein material that interacts with living cells without being absorbed by them can influence cell signaling, a new study shows.
Bio Pharma Dive
NOVEMBER 13, 2020
An alliance with BeyondSpring spinout Seed Therapeutics makes Eli Lilly the latest pharma company to dive into the fast-emerging drug research field
Scienmag
APRIL 5, 2021
– Researchers in the Oregon State University College of Science have taken a key step toward new drugs and vaccines for combating COVID-19 with a deep dive into one protein’s interactions with SARS-CoV-2 genetic material. Credit: OSU College of Science CORVALLIS, Ore.
Scienmag
DECEMBER 7, 2020
Louis and of immunology and internal medicine at the School of Medicine, and his team are experts in footprinting proteins — that is, using advanced methods for investigating the structure and interactions of proteins within larger molecules. Michael Gross, professor of chemistry in Arts & Sciences at Washington University in St.
Scienmag
APRIL 16, 2021
Study shines light on how tau aggregates promote neurodegeneration Look deep inside the brain of someone with Alzheimer’s disease, most forms of dementia or the concussion-related syndrome known as chronic traumatic encephalopathy (CTE) and you’ll find a common suspected culprit: stringy, hairball-like tangles of a protein called tau.
Scienmag
MARCH 31, 2021
Oak Brook, IL – The April edition of SLAS Discovery is a special issue on advances in protein degradation curated by guest editors M. Targeted protein degradation has generated interest within the drug discovery arena due to the inhibition of one particular function of a protein not […]. Paola Castaldi, Ph.D., and Stewart L. Fisher, Ph.D.
Scienmag
DECEMBER 28, 2020
Investigations of a cellular protein have uncovered a possible link with schizophrenia Credit: Mindy Takamiya/Kyoto University iCeMS Scientists have suspected mutations in a cellular cholesterol transport protein are associated with psychiatric disorders, but have found it difficult to prove this and to pinpoint how it happens.
BioTech 365
APRIL 14, 2021
Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Programming proteins to turn cells into molecular computers.A new method of breaking and fixing proteins could speed the development of sophisticated computer-like circuits in cells that will … Continue reading → #news
Scienmag
DECEMBER 2, 2020
Credit: University of Leeds A visualisation made from nearly 100,000 electron microscope images has revealed the ingenious way a protein involved in muscle activity shuts itself down to conserve energy.
Scienmag
APRIL 2, 2021
Scientists from Japan employ a novel two-step method of labeling neurotransmitter receptor proteins to track their localization efficiently Credit: Shigeki Kiyonaka The neurons in our nervous system “talk” to each other by sending and receiving chemical messages called neurotransmitters.
Scienmag
MARCH 18, 2021
— Scientists at the University of Wisconsin-Madison have developed a way to use a cell’s own recycling machinery to destroy disease-causing proteins, a technology that could produce entirely new kinds of drugs. Some cancers, for instance, are associated with abnormal proteins or an excess of normally harmless proteins. MADISON, Wis.
Scienmag
OCTOBER 21, 2020
Comprised of only 29 proteins (compared to our 400,000), with a genome 1/200,000 the size of ours, […].
Scienmag
DECEMBER 24, 2020
How tightly cells clump together, known as cell adhesion, appears to be enabled by a protein better known for its role in the immune system.
Scienmag
APRIL 12, 2021
Credit: POSTECH Blood vessels deliver nutrients and oxygen to each organ in our body. They are difficult to completely restore to their original conditions once damaged by myocardial infarction or severe ischemic diseases.
Scienmag
AUGUST 28, 2020
Credit: OIST A protein that’s common throughout the body plays a key role in regulating glucose levels, says new research conducted in the Cell Signal Unit at the Okinawa Institute of Science and Technology Graduate University (OIST) and Riken Center of Integrative Medical Sciences.
Scienmag
JANUARY 14, 2021
Credit: University of Leeds The UK’s leading scientific academy – the Royal Society – has awarded one of its most prestigious research professorships to an academic at the University of Leeds, to develop new ways of ‘seeing the unseen’ – the way that proteins interact to shape or to destroy memories.
Scienmag
JANUARY 7, 2021
Credit: Proceedings of the National Academy of Sciences Ribosomes are the complexes of ribonucleoproteins at the heart of protein synthesis in cells.
Scienmag
APRIL 14, 2021
Credit: Surajit Chatterjee To better understand how RNA in bacteria gives rise to protein–and along the way, target these processes in the design of new antibiotics–researchers are turning their attention to the unique way this process happens in bacteria.
Scienmag
FEBRUARY 24, 2021
24, 2021 — Postmenopausal women who ate high levels of plant protein had lower risks of premature death, cardiovascular disease and dementia-related death compared with women who ate less plant proteins, according to new research published today in the Journal of the American Heart Association, an […]. Journal of the American Heart Association report DALLAS, Feb.
BioTech 365
MARCH 3, 2021
Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Inhibiting pancreatic cancer by exploiting a protein loophole.Inhibiting pancreatic cancer by exploiting a protein loophole aliu Wed, 03/03/2021 – 05:24 from FierceBiotech: Biotech [link].
Scienmag
SEPTEMBER 9, 2020
Credit: © 2020 KAUST Purifying specific protein molecules from complex mixtures will become easier with a simpler way to detect a molecular “tag” commonly used as a handle to grab the proteins.
Scienmag
SEPTEMBER 21, 2020
Credit: Graphic by Shireen Dooling Often considered the workhorses of the body, proteins are among the most important biomolecules critical to life processes.
Scienmag
APRIL 1, 2021
Blanc, Michael Gecht, Roberto Covino and Gerhard Hummer A new, detailed model of the surface of the SARS-CoV-2 spike protein reveals previously unknown vulnerabilities that could inform development of vaccines.
BioTech 365
FEBRUARY 1, 2021
Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Supersaturation: The barrier between protein folding and misfolding.Correct, or native, protein folding is essential for correct protein function. Protein misfolding can lead to the formation of amyloid … Continue reading → #news
Scienmag
FEBRUARY 23, 2021
February 23, 2021) – The Gates Biomanufacturing Facility (GBF) has completed the manufacturing and release of a protein-based biologic under Good Manufacturing Practice for Phase 1 Investigational Drugs for first-in-human clinical trials. Manufacturing of this investigational, protein product demonstrates the GBF’s capacity to support both academic endeavors from Colorado’s university research centers and […]. Aurora, Colo.
Scienmag
NOVEMBER 10, 2020
Credit: WEHI, Australia The latest animation technology has revealed the molecular detail of how our bodies are protected from cancer by a key ‘tumour suppressor’ protein called p53. The new WEHI-TV animation visualises discoveries from more than 40 years of research to explain how the tumour suppressor protein p53 normally prevents cancer-causing changes in cells. […].
Scienmag
NOVEMBER 2, 2020
The study, published in Nature Communications, shows how bacterial protein ‘cages’ can be reprogrammed as nanoscale bioreactors for hydrogen production.
Scienmag
SEPTEMBER 9, 2020
Researchers from Aarhus University have developed a tool, ODiNPred, for prediction of the degree of structural order and disorder in proteins, by using machine learning together with experimental NMR data for hundreds of proteins.
Scienmag
MARCH 29, 2021
Credit: Pixabay/Yen Strandqvist, Chalmers University of Technology Artificial Intelligence is now capable of generating novel, functionally active proteins, thanks to recently published work by researchers from Chalmers University of Technology, Sweden.
Scienmag
OCTOBER 23, 2020
and Alessandra Villa – alessandra.villa@philogen.com Oncotarget recently published “A novel format for recombinant antibody-interleukin-2 fusion proteins […].
BioTech 365
NOVEMBER 9, 2020
NanoString Launches GeoMx DSP Protein Assays for Next Generation Sequencing NanoString Launches GeoMx DSP Protein Assays for Next Generation Sequencing GeoMx Digital Spatial Profiler (DSP) Now Enables Multi-Analyte Spatial Analysis Using Both NGS and nCounter Read-outs SEATTLE–(BUSINESS WIRE)–NanoString Technologies, Inc.
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