Protein - Clinical Research Informer

At EpiBiologics, a pair of Genentech alumni wants to make next-gen protein degraders

Bio Pharma Dive

MARCH 22, 2023

Armed with a $50 million Series A round, the startup is building off of research from a lab run by protein engineering pioneer Jim Wells.

Protein

Protein Engineer Research

Lilly puts more money into protein degradation

Bio Pharma Dive

AUGUST 25, 2021

The pharma has struck its second research pact focused on drugs that break down harmful proteins in as many years, this time with California biotech Lycia Therapeutics.

Protein

Protein Drugs Research

Gladstone and UCSF scientists discover BET protein role in Covid-19

Pharmaceutical Technology

JULY 20, 2022

Researchers at Gladstone Institutes and UC San Francisco (UCSF) have discovered in a study that bromodomain and extraterminal (BET) proteins are vital for the body to fight Covid-19 infection. . The research also found that BET proteins play two distinct roles in affecting how the SARS-CoV-2 virus interacts with human cells. .

Protein

Protein Scientist Gene DNA

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ALS drugmakers, encouraged by recent FDA feedback, set their sights on a key protein

Bio Pharma Dive

MARCH 27, 2023

A closely watched meeting showed the FDA’s own external advisers think that effects on this protein, known as neurofilament, could be enough to warrant conditional approval of certain drugs.

Protein

Protein Drugs

Why Is Faba Bean Protein Gaining Popularity in the Food Industry?

XTalks

APRIL 29, 2025

Faba bean protein, derived from Vicia faba , is emerging as a high-quality, sustainable plant-based protein that is rapidly gaining traction in the food industry. Faba beans contain up to 30% protein and an impressive amino acid profile that rivals that of both soy and animal proteins. This protein is also high quality.

Protein

Protein Production Containment Manufacturing

Touting a new way to drug an all-important family of proteins, a startup launches with $100M

Bio Pharma Dive

JANUARY 27, 2022

Backed by some of biotech's most powerful investors, Septerna is looking to usher in the next chapter of medicines that act on G protein-coupled receptors.

Protein

Protein Medicine Drugs

This Protein May Protect Against Alzheimer’s, Scientists Say

AuroBlog - Aurous Healthcare Clinical Trials blog

OCTOBER 16, 2023

In the search for a treatment for Alzheimer’s disease, researchers have zeroed in on a protein with protective effects. A new study reveals how cholesterol and inflammation in different types of human brain cells interact with a protein called ABCA7, which regulates how molecules pass through cell membranes.

Protein

Protein Scientist Regulation Research

Hunting Host Cell Proteins (HCPs) with mass spectrometry

Bio Pharma Dive

JULY 24, 2023

Regulators are recognizing mass spectrometry as a powerful tool in Host Cell Protein analysis. Are you ready to implement HCP-MS?

Protein

Protein Regulation

AbbVie, targeting a well-known protein family, expands a partnership into neuroscience

Bio Pharma Dive

AUGUST 2, 2022

It’s the second deal in as many years between AbbVie and Sosei Heptares, which together have been trying to develop drugs that target so-called G protein-coupled receptors.

Protein

Protein Development Drugs

This Protein Could Help Us Unravel The Mystery of Alzheimer’s

AuroBlog - Aurous Healthcare Clinical Trials blog

MAY 28, 2024

The new research centers on the protein contactin-4 (CNTN4) – thought to play a role in neuronal network […] There are a lot of connected, moving biological parts in our brains, which makes the study of brain diseases particularly challenging.

Protein

Protein Research Clinical Trials Clinical Trials

Blocking a Single Protein Could Prevent Nerve Damage Responsible For Alzheimer’s

AuroBlog - Aurous Healthcare Clinical Trials blog

MARCH 10, 2024

Scientists have identified a key protein in the development of Alzheimer’s disease which could prove critical in slowing or even halting the condition’s progress.

Protein

Protein Scientist Research Development

A Common Sleeping Pill May Reduce Buildup of Alzheimer’s Proteins, Study Finds

AuroBlog - Aurous Healthcare Clinical Trials blog

SEPTEMBER 8, 2024

In a study published in 2023, scientists found that using sleeping pills to get some shut-eye could reduce the build-up of toxic clumps of proteins […]

Protein

Protein Scientist Research Clinical Trials

Novartis-linked startup launches with technology designed to remove ‘destroy’ tags on helpful proteins

Bio Pharma Dive

JULY 28, 2022

Vicinitas and its protein-stabilizing research have attracted $65 million from a group of investors that includes a16z, Deerfield and GV.

Protein

Protein Research

Flashing Lights And a Clicking Sound Cleared Toxic Proteins in Alzheimer’s Mice

AuroBlog - Aurous Healthcare Clinical Trials blog

MARCH 7, 2024

Scientists have now demonstrated how stimulating high-frequency brain waves in mice can clear out the amyloid protein clumps associated with Alzheimer’s. Could Alzheimer’s disease one day be treated by flashes of light and clicks of sound?

Protein

Protein Scientist Research Clinical Trials

GPCR-targeting drugs: A renewed focus on a ubiquitous group of proteins

Bio Pharma Dive

MARCH 7, 2023

As many as a third of FDA-approved drugs target GPCRs in some fashion, with uses ranging from treating cancer to pain. But biotech startups say there is still room to develop more.

Protein

Protein FDA Approval Drugs Development

With $81M, Entact Bio takes a new approach to fixing helpful proteins

Bio Pharma Dive

DECEMBER 6, 2022

Entact Bio aims to develop medicines that can enhance helpful proteins, rather than block harmful ones, a twist on the usual drugmaking playbook.

Protein

Protein Medicine Development

AI tool could help doctors ID breast cancers vulnerable to Enhertu

Bio Pharma Dive

MAY 22, 2025

Tumors with low- and ultra-low levels of a protein called HER2 are treatable with Enhertu, but harder to identify. New research shows AI can improve diagnosis.

Doctors

Doctors Doctor Protein Research

Rotavirus protein NSP4 manipulates calcium signaling, affecting disease outcomes

Medical Xpress

JANUARY 18, 2025

The study published in Science Advances is among the first to show that the rotavirus protein NSP4 is both necessary and sufficient for multiple aspects of rotavirus infection by disrupting calcium signaling not only within infected cells but also in nearby uninfected cells.

Protein

Protein Medicine Research

Faba Bean Protein: Overcoming Formulation Challenges in Protein-Enriched Food Applications

XTalks

MARCH 18, 2025

In today’s food and beverage industry, protein enrichment has become a pivotal trend, driven by consumers’ growing awareness of health and nutrition. High-protein products are in demand across various categories, from bakery and dairy (alternatives) to sports nutrition and savoury foods.

Protein

Protein Manufacturing Production Branding

For The First Time, Scientists Capture The Protein-Lipid Dance on Video

AuroBlog - Aurous Healthcare Clinical Trials blog

APRIL 28, 2024

Our bodies are alive with activity and packed with proteins jammed into fatty membranes or floating in and out of watery cells. Scientists have now, for the first time, captured the dance between the two: a liquid tango featuring proteins and fats as they would normally move in cells.

Protein

Protein Scientist Clinical Trials Clinical Trials

A new biotech, built around protein design, springs from David Baker’s lab

Bio Pharma Dive

OCTOBER 30, 2024

Archon Biosciences, co-founded by the winner of the 2024 Nobel Prize in Chemistry, emerged from stealth Wednesday with $20 million in seed capital.

Protein

Astellas delves deeper into protein degrading drugs with Cullgen deal

Bio Pharma Dive

JUNE 14, 2023

The alliance is Astellas’ second recent partnership involving protein degraders, an emerging area of drug research the company has made a focus in recent years.

Protein

Protein Drugs Research

Initial launches with $75M and a new idea for targeting problematic proteins

Bio Pharma Dive

MAY 1, 2023

The company was co-founded by, among others, Jamie Cate, husband of CRISPR pioneer Jennifer Doudna, and Kevan Shokat, a chemical biologist whose previous work helped lead to KRAS-targeting cancer drugs.

Protein

Protein Drugs

Faba Bean Protein in Savoury Applications: The Next-Gen Solution

XTalks

APRIL 22, 2025

As consumer interest in protein-enriched foods continues to grow, food manufacturers are increasingly seeking high-quality, functional ingredients that enhance both nutrition and sensory appeal. Plant-based proteins are interesting as versatile solutions for a wide range of food applications.

Protein

Protein Manufacturing Production Marketing

Putative Fidgetin Like Protein 2 drugs in development, 2024

Pharmaceutical Technology

AUGUST 29, 2024

The Putative Fidgetin Like Protein 2 pipeline drugs market research report outlays comprehensive information on the Putative Fidgetin Like Protein…

Protein

Protein Drugs Development Marketing

Myotonin Protein Kinase drugs in development, 2024

Pharmaceutical Technology

AUGUST 29, 2024

GlobalData’s report assesses the drugs in the Myotonin Protein Kinase pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline.

Protein

Protein Development Drugs

Transmembrane Protein PVRIG drugs in development, 2024

Pharmaceutical Technology

AUGUST 29, 2024

GlobalData’s report assesses the drugs in the Transmembrane Protein PVRIG pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline.

Protein

Protein Development Drugs

Generate:Biomedicines and Novartis link on protein therapeutics development

Pharmaceutical Technology

SEPTEMBER 25, 2024

Generate:Biomedicines and Novartis have partnered for the discovery and development of protein therapeutics in multiple disease areas.

Protein

Protein Development

Teva puts rival to Prometheus, Pfizer drugs at center of turnaround plans

Bio Pharma Dive

MAY 18, 2023

At an investor day, executives highlighted an experimental inflammatory disease drug targeting the protein TL1A as important to their long-term growth prospects.

Drugs

Drugs Protein

Relay's targeted cancer drug could be safer than its competitors. Is it more effective?

Bio Pharma Dive

OCTOBER 8, 2021

Initial study results for Relay's experimental treatment offer some support for the biotech's protein motion technology, but raise some questions, too.

Protein

Protein Drugs

E3 Ubiquitin Protein Ligase CBL B drugs in development, 2024

Pharmaceutical Technology

AUGUST 29, 2024

GlobalData’s report assesses the drugs in the E3 Ubiquitin Protein Ligase CBL B pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline.

Protein

Protein Development Drugs

J&J-backed startup launches with $100M to build better brain drugs

Bio Pharma Dive

MARCH 7, 2023

Rapport Therapeutics aims to find new so-called receptor-associated proteins that could serve as targets for neurological disease medicines. Its most advanced drug is already in early-stage human testing.

Drugs

Drugs Protein Medicine

Pfizer stocks cancer drug pipeline with $2.3B deal for Trillium

Bio Pharma Dive

AUGUST 23, 2021

The acquisition reflects growing industry interest in the cancer-linked protein targeted by Trillium's drugs, most notably shown by Gilead's acquisition of Forty Seven last year.

Drugs

Drugs Protein

Roche licenses Sangamo’s technology for another shot at Alzheimer’s drugs

Bio Pharma Dive

AUGUST 6, 2024

Through a new deal, Roche has exclusive rights to Sangamo molecules designed to repress the gene that makes “tau,” a protein many scientists view as a main driver of Alzheimer’s.

Licensing

Licensing Licensing Protein Gene

With new startup, immunotherapy pioneer Lieping Chen tries to turn ‘cold’ tumors ‘hot’

Bio Pharma Dive

OCTOBER 25, 2022

Chen, who discovered the cancer-protecting protein PD-L1, will work closely with startup Normunity to find targets that can help the immune system reach ‘cold’ tumors.

Protein

Bristol Myers pays Agenus $200M for drug aimed at top immunotherapy target

Bio Pharma Dive

MAY 18, 2021

The pharma acquired rights to an experimental antibody medicine that blocks a protein, called TIGIT, that's become a focus for several cancer drugmakers.

Protein

Protein Antibody Medicine Drugs

FDA lifts hold on PTC Huntington’s disease trial

Bio Pharma Dive

JUNE 20, 2024

The agency has lifted a partial trial suspension based on one-year data showing PTC’s pill suppressed a key protein associated with the disorder.

Trials

Trials Protein

FDA approves new ALS medicine in precedent-setting decision

Bio Pharma Dive

APRIL 25, 2023

Biogen’s drug failed the key study meant to show it can slow the nerve-destroying disease, but the drug’s effect on a protein of interest led the FDA to conditionally clear it for market.

FDA Approval

FDA Approval Medicine Protein Marketing

Roche Alzheimer's study fails in another setback to a long-tested hypothesis

Bio Pharma Dive

JUNE 16, 2022

The failure is an upset not only to Roche, but also a blow to the wider Alzheimer’s research field, which has for years kept focus on a protein called beta amyloid.

Protein

Protein Research

Outrun Therapeutics announces launch with $10m seed funding

Pharmaceutical Technology

APRIL 18, 2024

Outrun Therapeutics announced its launch with $10m seed funding to advance a protein stabilisation pipeline focused on E3 ligase inhibitors.

Protein

UniQure's gene therapy for hemophilia B meets first goal in key study

Bio Pharma Dive

NOVEMBER 19, 2020

The results are first to emerge from a late-stage test of a hemophilia B gene therapy, and show UniQure's treatment can restore clotting protein levels to mild or even near normal levels.

Gene Therapy

Gene Therapy Gene Protein

Huadong Medicine gets grant for multi-domain active protein for treating metabolic diseases

Pharmaceutical Technology

APRIL 18, 2024

Discover the groundbreaking multi-domain active protein patented by Huadong Medicine Co Ltd for treating metabolic diseases. With increased efficacy and simplified preparation process, this protein is set to revolutionize existing treatments.

Protein

Protein Medicine

Fresh data show UniQure's hemophilia gene therapy appears to hold up

Bio Pharma Dive

DECEMBER 9, 2021

The amount of blood clotting protein found in patients who received the medicine was nearly the same at six months and 18 months post-treatment, according to results disclosed Thursday.

Gene Therapy

Gene Therapy Gene Protein Medicine

Generative AI-focused biotech startup Evozyne raises $81m

Pharmaceutical Technology

SEPTEMBER 28, 2023

The company’s algorithms put proteins through millions of years of simulated evolution to identify potential functional candidates.

Protein

At EpiBiologics, a pair of Genentech alumni wants to make next-gen protein degraders

Lilly puts more money into protein degradation

Webinars

Trending Sources

Gladstone and UCSF scientists discover BET protein role in Covid-19

Webinars

ALS drugmakers, encouraged by recent FDA feedback, set their sights on a key protein

Why Is Faba Bean Protein Gaining Popularity in the Food Industry?

Touting a new way to drug an all-important family of proteins, a startup launches with $100M

This Protein May Protect Against Alzheimer’s, Scientists Say

Hunting Host Cell Proteins (HCPs) with mass spectrometry

AbbVie, targeting a well-known protein family, expands a partnership into neuroscience

This Protein Could Help Us Unravel The Mystery of Alzheimer’s

Blocking a Single Protein Could Prevent Nerve Damage Responsible For Alzheimer’s

A Common Sleeping Pill May Reduce Buildup of Alzheimer’s Proteins, Study Finds

Novartis-linked startup launches with technology designed to remove ‘destroy’ tags on helpful proteins

Flashing Lights And a Clicking Sound Cleared Toxic Proteins in Alzheimer’s Mice

GPCR-targeting drugs: A renewed focus on a ubiquitous group of proteins

With $81M, Entact Bio takes a new approach to fixing helpful proteins

AI tool could help doctors ID breast cancers vulnerable to Enhertu

Rotavirus protein NSP4 manipulates calcium signaling, affecting disease outcomes

Faba Bean Protein: Overcoming Formulation Challenges in Protein-Enriched Food Applications

For The First Time, Scientists Capture The Protein-Lipid Dance on Video

A new biotech, built around protein design, springs from David Baker’s lab

Astellas delves deeper into protein degrading drugs with Cullgen deal

Initial launches with $75M and a new idea for targeting problematic proteins

Faba Bean Protein in Savoury Applications: The Next-Gen Solution

Putative Fidgetin Like Protein 2 drugs in development, 2024

Myotonin Protein Kinase drugs in development, 2024

Transmembrane Protein PVRIG drugs in development, 2024

Generate:Biomedicines and Novartis link on protein therapeutics development

Teva puts rival to Prometheus, Pfizer drugs at center of turnaround plans

Relay's targeted cancer drug could be safer than its competitors. Is it more effective?

E3 Ubiquitin Protein Ligase CBL B drugs in development, 2024

J&J-backed startup launches with $100M to build better brain drugs

Pfizer stocks cancer drug pipeline with $2.3B deal for Trillium

Roche licenses Sangamo’s technology for another shot at Alzheimer’s drugs

With new startup, immunotherapy pioneer Lieping Chen tries to turn ‘cold’ tumors ‘hot’

Bristol Myers pays Agenus $200M for drug aimed at top immunotherapy target

FDA lifts hold on PTC Huntington’s disease trial

FDA approves new ALS medicine in precedent-setting decision

Roche Alzheimer's study fails in another setback to a long-tested hypothesis

Outrun Therapeutics announces launch with $10m seed funding

UniQure's gene therapy for hemophilia B meets first goal in key study

Huadong Medicine gets grant for multi-domain active protein for treating metabolic diseases

Fresh data show UniQure's hemophilia gene therapy appears to hold up

Generative AI-focused biotech startup Evozyne raises $81m

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