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The evolution of assays for immuno-oncology research

Drug Discovery World

Genetically engineered mouse models (GEMM) recapitulate the stromal biology of different human cancers including the tumour microenvironment that regulates the disease process. Reagents that can augment and enhance ADCC are of interest in addition to the antibodies themselves. EMBO Mol Med 2017;9:137–53.doi:10.15252/emmm.201606857pmid:[link]