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Arrayjet announces collaboration with Chemspace

Drug Discovery World

Chemspace’s compound libraries are now accessible through Arrayjet’s SMM CRO/CMO services for assay development, contract screening and contract array manufacturing. SMMs enable high-throughput screening of compound libraries against targets of interest. PROTAC), and training AI drug discovery models.

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Taking a new approach to tackle neurodegenerative diseases

Drug Discovery World

William Erhardt , President, Head of Development & Operations of biotech Oligomerix, tells Lu Rahman about the company’s differentiated approach to developing disease-modifying therapeutics for neurodegenerative diseases. . Overcoming sector challenges . Furthermore, the global need is about seven times greater than the US.

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Informatics helps virtual biotech bring compound to clinical trial

Drug Discovery World

Libra Therapeutics is a San Diego-based biotech focused on developing novel disease-modifying therapeutics, which restore the cellular balance that is disrupted in neurodegenerative diseases. Libra’s pipeline targets mechanisms that can mitigate protein pathology associated with CNS degenerative disorders.

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AI use in repurposing drugs for Covid-19

Drug Discovery World

We witnessed the unprecedented pace of vaccine development, fuelled by cutting-edge mRNA technology. Our goal was to quickly identify existing therapeutics that could be repurposed for Covid-19 treatment by screening a library of approved and late-stage development drugs against a disease model in our platform.

Drugs 59
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Re-assessing the risks of drug-induced arrhythmias during drug discovery

Drug Discovery World

Although such electrophysiological systems may be more predictive of potential cardiac safety and efficacy than non-functional binding assays, many apparently attractive new drugs are still being discontinued later in development. Unexpected late-stage failures in drug development are, of course, the costliest.

Drugs 52