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Arrayjet announces collaboration with Chemspace

Drug Discovery World

Compounds can be printed neat at 10mM in dimethyl sulfoxide (DMSO), and a unique data point is generated per target-ligand interaction. The technique is suited for targeting proteins and structured RNA, developing heterobifunctional degrader molecules (e.g., PROTAC), and training AI drug discovery models.

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Taking a new approach to tackle neurodegenerative diseases

Drug Discovery World

New York-based Oligomerix is an emerging clinical-stage biotechnology company focused on developing disease-modifying therapeutics for neurodegenerative diseases characterised by aberrant tau protein ranging from rare tauopathies such as progressive supranuclear palsy (PSP) and frontotemporal dementia (FTD) to Alzheimer’s disease (AD).

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AI use in repurposing drugs for Covid-19

Drug Discovery World

In 2020, AI models predicted the efficacy of repurposed drugs for Covid-19. Our core technology uses machine learning (ML) models on image-based measurements of cellular morphology to broadly explore biology and chemistry and accelerate drug discovery efforts. Clinical trials revealed eight out of nine predictions were correct.

Drugs 59
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Re-assessing the risks of drug-induced arrhythmias during drug discovery

Drug Discovery World

Can potentially lethal arrhythmias induced by novel drugs be better predicted by using more relevant and sophisticated electrophysiological screening methods? Such techniques, if routinely deployed in drug discovery, may enable improved decision making in predicting serious adverse cardiovascular events.

Drugs 52
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Informatics helps virtual biotech bring compound to clinical trial

Drug Discovery World

This article is sponsored by Collaborative Drug Discovery. Libra’s pipeline targets mechanisms that can mitigate protein pathology associated with CNS degenerative disorders. About Collaborative Drug Discovery CDD provides a modern approach to drug discovery informatics that is trusted globally by thousands of leading researchers.