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Taking a new approach to tackle neurodegenerative diseases

Drug Discovery World

Using its proprietary compound screening platform, Oligomerix discovers and develops differentiated, oral, small molecule inhibitors of tau self-association that are easy to administer and cost-effective. . The post Taking a new approach to tackle neurodegenerative diseases appeared first on Drug Discovery World (DDW).

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Informatics helps virtual biotech bring compound to clinical trial

Drug Discovery World

This article is sponsored by Collaborative Drug Discovery. About Collaborative Drug Discovery CDD provides a modern approach to drug discovery informatics that is trusted globally by thousands of leading researchers. Libra is a completely virtual company, based on a “plug and play concept and mode of operation”, Gill explains.

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AI use in repurposing drugs for Covid-19

Drug Discovery World

In 2020, AI models predicted the efficacy of repurposed drugs for Covid-19. Clinical trials revealed eight out of nine predictions were correct. Our core technology uses machine learning (ML) models on image-based measurements of cellular morphology to broadly explore biology and chemistry and accelerate drug discovery efforts.

Drugs 59
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What to expect from drug discovery and development in 2023

Drug Discovery World

Even when those assets are excluded, the average ROI for 2021 was still double the 2022 projections.   “Aside from Covid-19, the fall in projected ROI has been driven by a combination of factors, ranging from high-value drugs securing approvals and entering commercialisation, to an increase in cycle times for drugs still in development.

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Re-assessing the risks of drug-induced arrhythmias during drug discovery

Drug Discovery World

Can potentially lethal arrhythmias induced by novel drugs be better predicted by using more relevant and sophisticated electrophysiological screening methods? Such techniques, if routinely deployed in drug discovery, may enable improved decision making in predicting serious adverse cardiovascular events.

Drugs 52