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The Utility of Liquid Biopsy in Oncology Clinical Trials

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Prospective clinical trials are needed to explore whether changing therapy based on ctDNA dynamics prior to radiologic or clinical progression will improve outcomes compared to our current standard,” added Dr. Bahassi. Also, exosomes are mostly being used for the detection of circulating RNA and microRNA. β€œAn

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Considerations for Neuroscience Trials with Intrathecal Delivery and Other Methods of Direct CNS Administration

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Such therapies may involve small interfering RNA (siRNA) or oligonucleotides in viral transfection platforms, large molecules and antibodies. A consideration is that for early-stage studies, the regulators usually are happier with a staged unilateral followed by a bilateral procedure to evaluate risks first,” explains Dr. Rodrigues.

Trials 83
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COVID-19 Pandemic Coverage

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The company’s candidate vaccine, mRNA-1273, is a synthetic messenger RNA that encodes the stabilized SARS-CoV-2 spike protein. Meanwhile, N95 masks are in such short supply that regulators have told healthcare workers they can be used multiple times with little evidence that disinfecting them works. Drugs and Vaccines.