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Perfusion MRI and Other Perfusion Imaging Techniques for Clinical Trials

XTalks

Magnetic resonance imaging (MRI) has had a part in clinical trials for more than three decades now. For most of this time, MRI mainly was used for qualitative interpretation and simple structural measurements. Various perfusion-related parameters can be measured using dynamic contrast-enhanced MRI (DCE-MRI).

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AAIC 2021: Six Ways the Approval of Aducanumab Will Change Alzheimer’s Clinical Trials

XTalks

Since amyloid-related imaging abnormalities (ARIA) were observed as adverse events in trials of aducanumab, studies in which patients are permitted to take the drug as a background therapy must now contend with the challenges of safety monitoring for this side effect. Safety Monitoring Considerations.