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Asthma Drug Xolair Wins FDA Approval as First Treatment for Multiple Food Allergies

XTalks

The class of IgE-mediated food allergies includes 160 foods, with peanuts, milk, eggs, wheat, soy and tree nuts being the most common ones. According to the Centers for Disease Control and Prevention (CDC), almost six percent of people in the US in 2021 had a food allergy. However, the treatment is restricted to peanut allergy.

Allergies 100
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One dose of Regeneron’s COVID antibody protects for eight months

pharmaphorum

A single dose of the COVID-19 monoclonal antibody therapy developing Regeneron reduced the risk of contracting the virus by around 82% for up to eight months, according to new trial data. The post One dose of Regeneron’s COVID antibody protects for eight months appeared first on. That was down from almost $2.6

Antibody 104
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Leo puts target on Dupixent in US as FDA clears tralokinumab

pharmaphorum

Sanofi and Regeneron have another challenger to their big-selling drug Dupixent for atopic dermatitis, now that the FDA has approved Leo Pharma’s rival antibody tralokinumab. It continues to grow strongly with Sanofi reporting a 53% rise in sales to more than $4.1 billion in the same year. billion in 2020. billion in 2020.

Sales 109
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Dupixent falls short in phase 3 chronic spontaneous urticaria trial

pharmaphorum

In CUPID STUDY B, IL-4 and IL-13 inhibitor Dupixent (dupilumab) wasn’t able to achieve a significant improvement in symptoms in Xolair-refractory CSU patients, and will be stopped for futility, although the antibody did show “numeric improvements” on itching and hive symptoms, according to its developers.

Trials 103
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AZ, Amgen get speedy FDA review for asthma drug tezepelumab

pharmaphorum

The FDA has started a priority review of AstraZeneca and Amgen’s severe asthma antibody tezepelumab, setting a date for a decision in the first quarter of 2022. Overall, the antibody cut the annual asthma exacerbation rate (AAER) by 56% over 52 weeks, which was consistent with the benefit seen in the phase 2 PATHWAY trial.

Drugs 52
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What to expect from PEGS Europe 2023: Day 2

Drug Discovery World

Ahead of protein and antibody engineering conference PEGS Europe 2024 in Lisbon, DDW’s Megan Thomas looks at what to expect from each track of the annual biologics technology meeting. Kielczewska will present: ‘Discovery of antibody-based therapeutics to challenging targets: Platform considerations’.

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Top 30 Pharma and Biotech Companies in 2023: Statistics and Trends

XTalks

Most of the company’s revenue comes from the manufacture and sale of biopharmaceutical products. billion in pharmaceutical sales from 2021. In contrast, several drugs experienced sale declines, such as Remicade (infliximab), an old immunology medication that continues to decline due to the rise of biosimilars since 2016.

Sales 98