TDP-43 DNA methylation may contribute to the mystery of age-dependent motor cortex involvement in ALS

Scienmag

Aging is a risk factor for the accumulation of TDP-43 (transduction responsive region DNA-binding protein of 43kDa) in the motor cortex. Biology agedependent ALS contribute cortex DNA involvement methylation motor mystery TDP43

DNA 91

Under the scanner: GIST scientists unravel the inner workings of DNA repair enzymes

Scienmag

DNA is the instruction manual for every living organism, guiding the development and functioning of all biological processes. In essence, it is a molecule with a double helix structure with each unit of a helix containing what are known as “DNA bases”.

DNA 77
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Collecting DNA from thin air

Pharma R&D Today

In a proof-of-concept study published this spring, researchers revealed that animal DNA can be collected from air sampling. The study’s authors have dubbed this DNA “airDNA,” and it could open up a lot of possibilities for better understanding the world around us.

DNA 52

DNA circuits

Scienmag

Changing the shape of soft matter using logic circuits made from DNA The myriad processes occurring in biological cells may seem unbelievably complex at first glance. And yet, in principle, they are merely a logical succession of events, and could even be used to form digital circuits. Researchers have now developed a molecular switching circuit […]. Technology and Engineering Chemistry/Physics/Materials Sciences Nanotechnology/Micromachines

DNA 62

DNA sensor quickly determines whether viruses are infectious

Scienmag

Technology and Engineering determines DNA infectious quickly sensor virusesCHAMPAIGN, Ill. — A new sensor can detect not only whether a virus is present, but whether it’s infectious – an important distinction for containing viral spread.

DNA 52

COVID prompts another milestone, as India clears first DNA vaccine

Pharma Phorum

The COVID-19 pandemic accelerated the development of mRNA-based vaccines, and its influence has now extended to DNA-based shots as well, with Zydus Cadila’s ZyCoV-D getting emergency use authorisation in India.

DNA 83

How DNA-encoded Libraries Boost Drug Discovery

Pharma R&D Today

DNA-encoded libraries (DELs) have been gaining a lot of traction in hit finding and drug discovery in recent years. Pharma R&D chemical libraries DEL DNA DNA encoded libraries Dr. Andreas Brunschweiger drug discovery library small molecules webinar

DNA 52

Ancient DNA rewrites early Japanese history — modern day populations have tripartite genetic origin

Scienmag

Ancient DNA extracted from human bones has rewritten early Japanese history by underlining that modern day populations in Japan have a tripartite genetic origin – a finding that refines previously accepted views of a dual genomic ancestry [Friday, 17th September 2021].

DNA 52

Zydus Cadila nears world-first human plasmid DNA vaccine approval

Pharma Phorum

Zydus Cadila has filed for emergency use approval (EUA) in India of its plasmid DNA-based vaccine for COVID-19, which if given a green light could become the first shot of its type to be cleared for widespread use in humans. .

DNA 82

How much does the DNA extraction route impact the results of microbiome research?

Scienmag

Biology DNA extraction impact microbiome research results routeLet’s face it, we are a results-driven society. Too focused on the outcome, people don’t often think about the “how.” For instance, did you think about “how” you got to work this morning or did you just get there?

DNA 52

Bradford scientists find DNA ‘switch’ in fight against cancer and dementia

Scienmag

Scientists from the University of Bradford have discovered a DNA protein ‘switch’ that could help in the treatment of cancer and dementia. Credit: University of Bradford Scientists from the University of Bradford have discovered a DNA protein ‘switch’ that could help in the treatment of cancer and dementia. Cancer Bradford cancer dementia DNA fight find scientists switch

DNA 40

Third Rock launches biotech targeting 'notoriously difficult' DNA regulators

Bio Pharma Dive

With $82 million in hand, Flare Therapeutics is looking to create precision cancer drugs by going after a type of protein called transcription factors

Origami with DNA

Scienmag

A team at TU Wien was able to answer important questions about the immune system – with a trick reminiscent of paper folding. Credit: TU Wien T-cells are an important component of our immune system: with the receptors they carry on their surface, they can recognise highly specific antigens.

DNA 86

Evonetix Granted Patent for DNA Data Storage and Retrieval Method

BioTech 365

DNA 52

Could DNA-based COVID-19 vaccine offer variant-busting booster shot?

BioPharma Reporter

With Scancell taking its DNA-based COVID-19 vaccine tech into clinical trials this year, it is already focusing its attention on the techâs potential to be used as a needle-free booster shot to address Variants of Concern.

DNA 105

Why Proviral DNA Drug Resistance Testing is Useful in Guiding Treatment Decisions for HIV-1 Patients

XTalks

However, the variant viral genomes will still persist in the latent reservoir as provirus and can be detected with proviral DNA testing. In contrast to HIV RNA, HIV proviral DNA remains present in a patient’s cells even during virological suppression. Proviral DNA Genotyping.

DNA 83

Applied DNA to Participate in Upcoming Conferences

BioTech 365

Applied DNA to Participate in Upcoming Conferences Applied DNA to Participate in Upcoming Conferences STONY BROOK, N.Y.–(BUSINESS –(BUSINESS WIRE)–$APDN #COVID19–Applied DNA Sciences, Inc.

DNA 52

Celsion DNA Vaccine Platform Produces Potent Response in Preclinical Study

BioSpace

Celsion announced results from its PLACCINE DNA vaccine platform that showed it produced antibodies and cytotoxic T-cell response specific to the spike antigen of SARS-CoV-2

Biologists find invasive snails using new DNA-detection technique

Scienmag

Biologists led by the University of Iowa discovered the presence of the invasive New Zealand mud snail by detecting their DNA in waters they were inhabiting incognito. The researchers employed a technique called environmental DNA (eDNA) to reveal the […].

DNA 83

PharmaCyte Biotech Announces Encapsulation Material Does Not Alter Cellular DNA

BioTech 365

PharmaCyte Biotech Announces Encapsulation Material Does Not Alter Cellular DNA PharmaCyte Biotech Announces Encapsulation Material Does Not Alter Cellular DNA LAGUNA HILLS, Calif.–(BUSINESS

DNA 52

Applied DNA Awarded Suffolk County Community College COVID-19 Testing Contract

BioTech 365

Applied DNA Awarded Suffolk County Community College COVID-19 Testing Contract Applied DNA Awarded Suffolk County Community College COVID-19 Testing Contract – Company’s safeCircle™ Testing Program to Monitor for COVID-19 Among On-Campus Unvaccinated Populations – STONY BROOK, N.Y.–(BUSINESS

DNA 52

Deluge of DNA changes drives progression of fatal melanomas

Scienmag

Credit: WEHI, Australia Melbourne researchers have revealed how melanoma cells are flooded with DNA changes as this skin cancer progresses from early, treatable stages through to fatal end-stage disease.

DNA 83

A new twist on DNA origami

Scienmag

DNA 81

USC researchers discover better way to identify DNA variants

Scienmag

USC researchers have achieved a better way to identify elusive DNA variants responsible for genetic changes affecting cell functions and diseases. Using computational biology tools, scientists at the university’s Dornsife College of Letters, Arts and Sciences studied “variable-number tandem repeats” (VNTR) in DNA. VNTRs are stretches of DNA made of a short pattern of nucleotides […].

DNA 63

DNA Script Exclusively Licenses baseclick GmbH Technology to Enable Benchtop Printing of Modified DNA On-Demand

BioTech 365

DNA Script Exclusively Licenses baseclick GmbH Technology to Enable Benchtop Printing of Modified DNA On-Demand DNA Script Exclusively Licenses baseclick GmbH Technology to Enable Benchtop Printing of Modified DNA On-Demand PARIS & SOUTH SAN FRANCISCO, Calif.–(BUSINESS

DNA 52

NIST publishes a beginner’s guide to DNA origami

Scienmag

Dill/NIST In a technique known as DNA origami, researchers fold long strands of DNA over and over again to construct a variety of tiny 3D structures, including miniature biosensors and drug-delivery containers. Credit: K.

DNA 83

Merck KGaA signs DNA damage response cancer deal with Artios Pharma

Pharma Phorum

Germany’s Merck KGaA has joined with UK-based Artios Pharma in a potential multi-billion dollar deal to investigate novel DNA damage response targets in cancer. The partnership will focus on nucleases, which cancer cells depend on for their survival to repair DNA damage.

DNA 80

Which Career Combines DNA Technology and Medicine?

BioSpace

Which career combines DNA technology and medicine? The answer to that question is medical genetics and the job titles involved around it. Some of the examples are clinical geneticists, genetics counselors and clinical laboratory geneticists

DNA analysis could pinpoint ‘long haulers’ among COVID-19 patients

Outsourcing Pharma

The analytical tool, developed via Bionano Genomics, maps structural variations in DNA that are known to cause disease and are tied to symptom severity.

Genome 114

DNA damage caused by migrating light energy

Scienmag

UV radiation modifies DNA also far away from the entry point of light – publication in Angewandte Chemie Credit: (Photo: Arthur Kuhlmann, KIT) Ultraviolet light endangers the integrity of human genetic information and may cause skin cancer.

DNA 71

Oncotarget: Genome wide DNA methylation landscape reveals glioblastoma’s influence

Scienmag

DNA 82

CLINUVEL expands DNA Repair Program

BioTech 365

CLINUVEL expands DNA Repair Program CLINUVEL expands DNA Repair Program SCENESSE® (afamelanotide 16mg) to be evaluated in xeroderma pigmentosum variant (XP-V) MELBOURNE, Australia, March 24, 2021 (GLOBE NEWSWIRE) — CLINUVEL has expanded its clinical program to evaluate the DNA reparative … Continue reading → GlobeNewswire

DNA 40

Chemical ‘nose’ sniffs critical differences in DNA structures

Scienmag

Detection innovation could enhance drug development and cancer research Credit: Richard Hooley/UCR Small changes in the structure of DNA have been implicated in breast cancer and other diseases, but they’ve been extremely difficult to detect — until now.

DNA 83

Mathur studying cytosolic access and instability of DNA nanoparticles

Scienmag

Divita Mathur, Research Assistant Professor, is studying cytosolic access and instability of DNA nanoparticles. Self-assembled deoxyribonucleic acid (DNA) […]. A number of candidate therapies such as CRISPR-Cas9 and gene silencing require the efficient delivery of functional nucleic acids to the cell cytosol and nucleus. Unfortunately, such therapies currently lack proper delivery mechanisms, precluding their widespread applicability.

Making 3D nanosuperconductors with DNA

Scienmag

DNA 56

DNA Data Storage Alliance Publishes First White Paper, Launches Website

BioTech 365

DNA Data Storage Alliance Publishes First White Paper, Launches Website DNA Data Storage Alliance Publishes First White Paper, Launches Website — New Storage Technologies Needed to Address Emerging Data Oceans — — Dense, Stable, Low Power Data Storage in DNA … Continue reading → Business Wire

DNA 52

X-Chem Announces OpenDEX DNA-Encoded Library Screening

BioTech 365

X-Chem Announces OpenDEX DNA-Encoded Library Screening X-Chem Announces OpenDEX DNA-Encoded Library Screening Flexible and Cost-Effective Solution for Screening Billions of Small Molecules WALTHAM, Mass.–(BUSINESS

DNA 52

RevoluGen’s Automated Fire Monkey HMW-DNA Extraction Validated on Tecan Robot Supports Rapid Growth in Multiplexed DNA Sequencing

BioTech 365

RevoluGen’s Automated Fire Monkey HMW-DNA Extraction Validated on Tecan Robot Supports Rapid Growth in Multiplexed DNA Sequencing RevoluGen’s Automated Fire Monkey HMW-DNA Extraction Validated on Tecan Robot Supports Rapid Growth in Multiplexed DNA Sequencing Proof of concept for automated Fire … Continue reading → Business Wire

DNA 52

Applied DNA Receives Purchase Orders Totaling $1.6 Million to Tag Textile Fibers

BioTech 365

Applied DNA Receives Purchase Orders Totaling $1.6 Million to Tag Textile Fibers Applied DNA Receives Purchase Orders Totaling $1.6

Touchlight extends funding round, sees hike in demand for synthetic DNA vectors

BioPharma Reporter

Synthetic DNA vector producer, Touchlight, has announced the extension of its fundraising round to a current aggregate total of US$125m (Â92m). The financing was led by Bridford Investments Limited and Novator Partners. Upstream Processing

DNA 80

The world’s first DNA ‘tricorder’ in your pocket

Scienmag

By pairing an iPhone with a handheld DNA sequencer, users can create a mobile genetics laboratory, reminiscent of the “tricorder” featured in Star Trek.

DNA 82

Codex DNA Announces Pricing of Initial Public Offering

BioTech 365

Codex DNA Announces Pricing of Initial Public Offering Codex DNA Announces Pricing of Initial Public Offering SAN DIEGO, June 17, 2021 (GLOBE NEWSWIRE) — Codex DNA, Inc. Codex DNA”), creators of the BioXp™ system, a fully automated benchtop instrument that … Continue reading → GlobeNewswire

DNA 40

Building tough 3D nanomaterials with DNA

Scienmag

Columbia Engineers use DNA nanotechnology to create highly resilient synthetic nanoparticle-based materials that can be processed through conventional nanofabrication methods Credit: Oleg Gang/Columbia Engineering New York, NY–March 19, 2020–Columbia Engineering researchers, working with Brookhaven National Laboratory, report today that they have built designed nanoparticle-based 3D materials that can withstand a vacuum, high temperatures, high pressure, […].

DNA 54