AuroBlog - Aurous Healthcare Clinical Trials blog

OCTOBER 17, 2022

Studies in mammals have shown that the ‘memories’ of various environmental effects – such as diet, weight, and stress – can be passed on from fathers to offspring, despite these effects not being coded for in the DNA sequences carried by sperm.

DNA 205

DNA Clinical Trials Clinical Trials Clinical Research 205

Outsourcing Pharma

SEPTEMBER 8, 2023

A benchtop DNA sequencer developed by the U.S. DNA sequencing company Element Biosciences, Inc., has seen sales grow by triple digits and has received more than 100 orders since its launch in March 2022.

DNA 86

DNA Sales Development Regulation 86

pharmaphorum

JULY 20, 2022

It has suspected for many years that some diseases may be linked to non-coding or ‘junk’ DNA, but the mechanism behind the pathology hasn’t been worked out. Junk DNA is a term used to describe the 97% of the genetic sequence in human cells found between the 3% coding for our 20,000 genes, once thought to be inert.

DNA 116

DNA Scientist Genome Genomics 116

Medical Xpress

NOVEMBER 18, 2022

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development.

DNA 91

DNA Vaccination Vaccine Scientist 91

Scienmag

JUNE 26, 2022

The monumental global task to restore degraded ecosystems will need to include sophisticated technologies such as environmental DNA monitoring to understand and support the recovery of complex biospheres, international researchers say.

DNA 91

DNA Research Engineer 91

Drug Discovery World

JULY 31, 2023

Matt Hill , Founder and CEO of Elegen writes about the importance of innovation in DNA synthesis to address critical bottlenecks in biotherapy development. Regardless of the type of disease targeted, at the core of biotherapy development is synthetic biology and the use of synthetic DNA to programme specific behaviours within living cells.

DNA 52

DNA Medicine Gene Vaccination 52

Medical Xpress

MAY 14, 2023

For two decades, scientists have been comparing every person's full set of DNA they study to a template that relies mostly on genetic material from one man affectionately known as "the guy from Buffalo."

DNA 98

DNA Scientist Genome Genomics 98

Outsourcing Pharma

JULY 18, 2023

company KSQ Therapeutics to co-develop KSQâs lead cancer drug, which is designed to sabotage the DNA repair mechanisms of cancer cells. Roche has entered a licensing and collaboration deal with the U.S.

DNA 87

DNA Licensing Licensing Drugs 87

Pharma Times

MAY 10, 2023

Transfer marks start of vital development stage as company expands its range of synthesized DNA

DNA 113

DNA Development 113

Roots Analysis

OCTOBER 16, 2023

DNA cloning refers to the process of generating multiple copies of a particular DNA segment. DNA and Gene Cloning involves the isolation of a DNA sequence of any species ( often a gene ) and its insertion into a vector to enable growth without any alteration in the original DNA sequence.

DNA 40

DNA Gene Protein In-Vitro 40

Medical Xpress

FEBRUARY 22, 2023

Mount Sinai researchers have published a study in Alzheimer's & Dementia: The Journal of the Alzheimer's Association that sheds new light on the role of DNA methylation in Alzheimer's disease (AD).

DNA 98

DNA Research Gene Protein 98

Drug Discovery World

MAY 11, 2023

The first DNA synthesised using Evonetix’s semiconductor chip technology has been delivered to the Department of Chemical Engineering and Biotechnology at the University of Cambridge. The DNA was delivered to Dr Jenny Molloy, Co-chair of the Engineering Biology Interdisciplinary Research Centre at the University of Cambridge.

DNA 52

DNA Engineer Gene Scientist 52

Pharma Times

NOVEMBER 29, 2022

Bill & Melinda Gates Foundation grant will boost potential of nanoparticle-formulated doggybone DNA

DNA 126

DNA Vaccination Vaccine 126

Pharma Times

OCTOBER 4, 2022

University of Lincoln and the University of Sheffield are researching how DNA could be repaired

DNA 145

DNA Research 145

Drug Discovery World

MAY 24, 2023

Touchlight, a company providing DNA services and manufacturing enzymes, has completed the redevelopment and expansion of its UK manufacturing facility in London, UK. The expanded facility’s manufacturing capacity has tripled and is now capable of producing more than 8kg a year.

DNA 52

DNA Gene Therapy Gene Editing Genetics 52

Medical Xpress

MAY 16, 2023

Cancer is caused by DNA changes that cause a cell to gradually change from benign to malignant. By studying the types of DNA changes and the consequences of the changes, important insights into the underlying biological processes were obtained. This can lead to metastases in other parts of the body.

DNA 98

DNA Research 98

BioPharma Reporter

FEBRUARY 2, 2023

mRNA pioneer BioNTech has completed construction of its first proprietary plasmid DNA manufacturing facility in Marburg, Germany.

DNA 112

DNA Manufacturing 112

Scienmag

JULY 19, 2022

Scientists have found that non-coding ‘junk’ DNA, far from being harmless and inert, could potentially contribute to the development of cancer. Their study has shown how non-coding DNA can get in the way of the replication and repair of our genome, potentially allowing mutations to accumulate.

DNA 68

DNA Genome Genomics Scientist 68

Medical Xpress

FEBRUARY 22, 2023

A new research paper was published in Aging, titled "Metformin use history and genome-wide DNA methylation profile: potential molecular mechanism for aging and longevity."

DNA 97

DNA Genome Genomics Research 97

Scienmag

MAY 9, 2022

HOUSTON – (May 9, 2022) – When cells reproduce, the internal mechanisms that copy DNA get it right nearly every time. Rice University bioscientists have uncovered a tiny detail that helps understand how the process could go wrong.

DNA 86

DNA 86

Scienmag

APRIL 7, 2022

Chemists integrated computer functions into rolling DNA-based motors, opening a new realm of possibilities for miniature, molecular robots. Nature Nanotechnology published the development, the first DNA-based motors that combine computational power with the ability to burn fuel and move in an intentional direction.

DNA 91

DNA Development Engineer 91

Medical Xpress

NOVEMBER 17, 2022

BRCA1 (BReast CAncer Gene 1), a key gene that becomes faulty in some instances, leading to breast and ovarian cancer, plays an important role in the body's DNA repair mechanisms. BRCA1, once mutated, can cause cancer to develop.

DNA 119

DNA Gene Production Development 119

Scienmag

NOVEMBER 30, 2021

30, 2021 — A new study led by University of California, Irvine researchers has confirmed a link between altered DNA repair and increased DNA damage associated with spinocerebellar ataxia type 7 (SCA7), a debilitating, sometimes deadly neurodegenerative condition causing movement disorders. Irvine, Calif.,

DNA 92

DNA Research Medicine 92

Pharma Times

AUGUST 16, 2022

Researchers are invited to apply to receive DNA that has been synthesised using Evonetix’s platform

DNA 107

DNA Research 107

STAT News

FEBRUARY 9, 2023

Or the baby girl who could have had a life-threatening reaction to anesthesia had researchers not sequenced her DNA ahead of time. They’ll tell you about the 3-month-old boy whose heart was failing until researchers pinpointed what was ailing him.

Genetic Disease 119

Genetic Disease Genetics DNA Genome 119

Drug Discovery World

AUGUST 16, 2023

Samir Ounzain , PhD, CEO & Co-Founder of HAYA Therapeutics, looks at how a better understanding of our DNA can lead to increased activity for RNA therapeutics. Many scientists are now discovering that this junk DNA plays an essential role in our biology and the epigenetic processes that respond to the environment to drive disease.

RNA 52

RNA Genome Genomics DNA 52

BioPharma Reporter

FEBRUARY 6, 2023

AstraZeneca has cut the cost and time needed to complete DNA synthesis by integrating an assembly framework into Benchling.

DNA 98

DNA Clinical Development Development 98

XTalks

DECEMBER 14, 2022

Developed by MIT researchers Jonathan Gootenberg and Omar Abudayyeh, PASTE (Programmable Addition via Site-specific Targeting Elements) gene editing technology can insert genes as long as 36,000 DNA base pairs to liver cells in mice as well as several types of human cells.

Gene Editing 98

Gene Editing Gene DNA Gene Sequencing 98

STAT News

JANUARY 10, 2023

Illumina, the largest maker of DNA sequencing technology, told investors exactly what they didn’t want to hear on Monday. For years, Illumina shares rose steadily as the company led the way on pushing down the costs involved in doing genetic research.

DNA 105

DNA Genetics Research 105

Medical Xpress

APRIL 17, 2023

A multi-institution study that included researchers from Stanford University, the University of California at San Diego, the University of Cambridge, the Fred Hutchinson Cancer Center and others has looked into the development of extrachromosomal DNA in patients with esophageal adenocarcinoma or Barrett's esophagus.

DNA 89

DNA Development Research 89

Scienmag

JUNE 3, 2022

Of these various macromolecules that form droplets, DNA is quite interesting because it is predictable and programmable, which are qualities useful in nanotechnology. Recently, the programmability of DNA was used to construct and regulate DNA droplets […].

DNA 75

DNA Life Science Regulation Research 75

Scienmag

JUNE 3, 2022

Researchers in Japan have discovered that the local DNA motion inside of human cells remains steady throughout interphase, where the cell grows and replicates its DNA for cell division. The study suggests that this steady-state DNA motion allows cells to conduct housekeeping tasks under similar environments during interphase.

DNA 80

DNA Research 80

Drug Discovery World

AUGUST 30, 2023

Immunomic Therapeutics has commenced its Phase I clinical trial evaluating ITI-1001, a plasmid DNA (pDNA) vaccine, for the treatment of Glioblastoma Multiforme (GBM), a rare but aggressive form of brain cancer. The post Plasmid DNA vaccine for brain cancer enters Phase I trial appeared first on Drug Discovery World (DDW).

DNA 52

DNA Vaccination Vaccine Trials 52

pharmaphorum

AUGUST 23, 2021

The COVID-19 pandemic accelerated the development of mRNA-based vaccines, and its influence has now extended to DNA-based shots as well, with Zydus Cadila’s ZyCoV-D getting emergency use authorisation in India. Proponents of the approach claim that DNA vaccines may have advantages over other technologies like mRNA.

DNA 98

DNA Vaccination Vaccine Genetic Engineering 98

BioSpace

NOVEMBER 13, 2022

Ionis Pharmaceuticals inked a collaboration deal with Metagenomi with the goal of adding DNA editing to its RNA-targeted technologies focused on up to four genetic targets.

DNA 98

DNA RNA Genetics 98

BioPharma Reporter

OCTOBER 5, 2023

Researchers from Chung-Ang University, Korea have developed a novel DNA biosensor which could result in early diagnosis of cervical cancer.

DNA 52

DNA Research Development Regulation 52

STAT News

SEPTEMBER 16, 2022

Intellia Therapeutics said Friday the first six patients to receive its CRISPR-based treatment for a genetic swelling disorder have safely had small, corrective changes made to dysfunctional DNA inside their liver cells.

DNA 142

DNA Gene Editing In-Vivo Gene 142