Third Rock launches biotech targeting 'notoriously difficult' DNA regulators

Bio Pharma Dive

With $82 million in hand, Flare Therapeutics is looking to create precision cancer drugs by going after a type of protein called transcription factors

How DNA-encoded Libraries Boost Drug Discovery

Pharma R&D Today

DNA-encoded libraries (DELs) have been gaining a lot of traction in hit finding and drug discovery in recent years. Pharma R&D chemical libraries DEL DNA DNA encoded libraries Dr. Andreas Brunschweiger drug discovery library small molecules webinar

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Origami with DNA

Scienmag

A team at TU Wien was able to answer important questions about the immune system – with a trick reminiscent of paper folding. Credit: TU Wien T-cells are an important component of our immune system: with the receptors they carry on their surface, they can recognise highly specific antigens.

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X-Chem Announces OpenDEX DNA-Encoded Library Screening

BioTech 365

X-Chem Announces OpenDEX DNA-Encoded Library Screening X-Chem Announces OpenDEX DNA-Encoded Library Screening Flexible and Cost-Effective Solution for Screening Billions of Small Molecules WALTHAM, Mass.–(BUSINESS

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Applied DNA to Participate in Upcoming Conferences

BioTech 365

Applied DNA to Participate in Upcoming Conferences Applied DNA to Participate in Upcoming Conferences STONY BROOK, N.Y.–(BUSINESS –(BUSINESS WIRE)–$APDN #COVID19–Applied DNA Sciences, Inc.

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Why Proviral DNA Drug Resistance Testing is Useful in Guiding Treatment Decisions for HIV-1 Patients

XTalks

However, the variant viral genomes will still persist in the latent reservoir as provirus and can be detected with proviral DNA testing. In contrast to HIV RNA, HIV proviral DNA remains present in a patient’s cells even during virological suppression. Proviral DNA Genotyping.

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DNA Script Exclusively Licenses baseclick GmbH Technology to Enable Benchtop Printing of Modified DNA On-Demand

BioTech 365

DNA Script Exclusively Licenses baseclick GmbH Technology to Enable Benchtop Printing of Modified DNA On-Demand DNA Script Exclusively Licenses baseclick GmbH Technology to Enable Benchtop Printing of Modified DNA On-Demand PARIS & SOUTH SAN FRANCISCO, Calif.–(BUSINESS

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CLINUVEL expands DNA Repair Program

BioTech 365

CLINUVEL expands DNA Repair Program CLINUVEL expands DNA Repair Program SCENESSE® (afamelanotide 16mg) to be evaluated in xeroderma pigmentosum variant (XP-V) MELBOURNE, Australia, March 24, 2021 (GLOBE NEWSWIRE) — CLINUVEL has expanded its clinical program to evaluate the DNA reparative … Continue reading → GlobeNewswire

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Merck KGaA signs DNA damage response cancer deal with Artios Pharma

Pharma Phorum

Germany’s Merck KGaA has joined with UK-based Artios Pharma in a potential multi-billion dollar deal to investigate novel DNA damage response targets in cancer. The partnership will focus on nucleases, which cancer cells depend on for their survival to repair DNA damage.

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DNA analysis could pinpoint ‘long haulers’ among COVID-19 patients

Outsourcing Pharma

The analytical tool, developed via Bionano Genomics, maps structural variations in DNA that are known to cause disease and are tied to symptom severity.

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#news #biotech Scientists reveal unprecedentedly versatile new DNA staining probe

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Scientists reveal unprecedentedly versatile new DNA staining probe.A group of scientists at Nagoya University, Japan, have developed an incredibly versatile DNA fluorescent dye, named ‘Kakshine’ after a … Continue reading → #news

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A new twist on DNA origami

Scienmag

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Chemical ‘nose’ sniffs critical differences in DNA structures

Scienmag

Detection innovation could enhance drug development and cancer research Credit: Richard Hooley/UCR Small changes in the structure of DNA have been implicated in breast cancer and other diseases, but they’ve been extremely difficult to detect — until now.

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RevoluGen’s Automated Fire Monkey HMW-DNA Extraction Validated on Tecan Robot Supports Rapid Growth in Multiplexed DNA Sequencing

BioTech 365

RevoluGen’s Automated Fire Monkey HMW-DNA Extraction Validated on Tecan Robot Supports Rapid Growth in Multiplexed DNA Sequencing RevoluGen’s Automated Fire Monkey HMW-DNA Extraction Validated on Tecan Robot Supports Rapid Growth in Multiplexed DNA Sequencing Proof of concept for automated Fire … Continue reading → Business Wire

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Deluge of DNA changes drives progression of fatal melanomas

Scienmag

Credit: WEHI, Australia Melbourne researchers have revealed how melanoma cells are flooded with DNA changes as this skin cancer progresses from early, treatable stages through to fatal end-stage disease.

Making 3D nanosuperconductors with DNA

Scienmag

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First member of ill-fated 1845 Franklin expedition is identified by DNA analysis

Scienmag

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Applied DNA CEO Discusses Relevance of DNA-based Cotton Traceability as Enabler of Ethical and Responsible Textile Manufacturing on BBC Business Daily

BioTech 365

Applied DNA CEO Discusses Relevance of DNA-based Cotton Traceability as Enabler of Ethical and Responsible Textile Manufacturing on BBC Business Daily Applied DNA CEO Discusses Relevance of DNA-based Cotton Traceability as Enabler of Ethical and Responsible Textile Manufacturing on BBC … Continue reading → Business Wire

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Inovio’s DNA Vaccine Generates Robust Responses Against COVID-19 Variants in Study

BioSpace

Shares of Inovio are climbing in early trading this morning after the company announced its DNA vaccine candidate for COVID-19 induced a robust T-cell response against multiple variants of the SARS-CoV-2 virus

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#news #biotech DNA methylation regulator QSER1 identified

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: DNA methylation regulator QSER1 identified.A has identified a DNA methylation regulator called QSER1. team of researchers from a number of institutions in the U.S. In their paper … Continue reading → #news

NIST publishes a beginner’s guide to DNA origami

Scienmag

Dill/NIST In a technique known as DNA origami, researchers fold long strands of DNA over and over again to construct a variety of tiny 3D structures, including miniature biosensors and drug-delivery containers. Credit: K.

DNA damage caused by migrating light energy

Scienmag

UV radiation modifies DNA also far away from the entry point of light – publication in Angewandte Chemie Credit: (Photo: Arthur Kuhlmann, KIT) Ultraviolet light endangers the integrity of human genetic information and may cause skin cancer.

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$609.8 Million Worldwide Recombinant DNA Technology Industry to 2027 – Impact of COVID-19 on the Market – ResearchAndMarkets.com

BioTech 365

Million Worldwide Recombinant DNA Technology Industry to 2027 – Impact of COVID-19 on the Market – ResearchAndMarkets.com $609.8 Million Worldwide Recombinant DNA Technology Industry to 2027 – Impact of COVID-19 on the Market – ResearchAndMarkets.com DUBLIN–(BUSINESS WIRE)–The “Recombinant DNA … Continue reading → Business Wire

The structure of DNA is found to be actively involved in genome regulation

Scienmag

The two meters of -stretched- DNA contained in human cells are continuously twisting and untwisting to give access to genetic information: when a gene is expressed to generate a protein, the two strands of DNA are separated to give access to all the machinery necessary for this expression, resulting in an excessive accumulation of coiling […].

#news #biotech Research advances emerging DNA sequencing technology

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Research advances emerging DNA sequencing technology.Nanopore technology shows promise for making it possible to develop small, portable, inexpensive devices that can sequence DNA in real time.

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History of giants in the gene: Scientists use DNA to trace the origins of giant viruses

Scienmag

Scientists investigate the evolution of Mimivirus, one of the world’s largest viruses, through how they replicate DNA Credit: Indian Institute of Technology Bombay 2003 was a big year for virologists.

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FDA Grants EUA to Applied DNA LineaTM COVID-19 Assay Kit for Asymptomatic Screening of Individuals with Serial Testing

BioTech 365

FDA Grants EUA to Applied DNA LineaTM COVID-19 Assay Kit for Asymptomatic Screening of Individuals with Serial Testing FDA Grants EUA to Applied DNA LineaTM COVID-19 Assay Kit for Asymptomatic Screening of Individuals with Serial Testing – Assay Kit Now … Continue reading → Business Wire

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Building tough 3D nanomaterials with DNA

Scienmag

Columbia Engineers use DNA nanotechnology to create highly resilient synthetic nanoparticle-based materials that can be processed through conventional nanofabrication methods Credit: Oleg Gang/Columbia Engineering New York, NY–March 19, 2020–Columbia Engineering researchers, working with Brookhaven National Laboratory, report today that they have built designed nanoparticle-based 3D materials that can withstand a vacuum, high temperatures, high pressure, […].

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Applied DNA and Northwell Health Establish SARS-CoV-2 Mutation and Variant Tracking Program

BioTech 365

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VCU technology could upend DNA sequencing for diagnosing certain DNA mutations

Scienmag

Credit: John Wallace, VCU Massey Cancer Center Doctors are increasingly using genetic signatures to diagnose diseases and determine the best course of care, but using DNA sequencing and other techniques to detect genomic rearrangements remains costly or limited in capabilities.

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PwC Pharma & Life Sciences Webinar: COVID-19 impact on the ITX and regulatory DNA – Thursday 28. May 2020, 10:30 CEST

Pharma Business Blog

In light of that, we would like to invite you to our Pharma & Life Science webinar where we and other industry professionals will be discussing the impact of COVID-19 on the ITX and regulatory DNA on the pharma and life science industry.

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PharmaJet Presents Needle-free Delivery of COVID-19 DNA Vaccine Results at World Vaccine Congress

BioTech 365

PharmaJet Presents Needle-free Delivery of COVID-19 DNA Vaccine Results at World Vaccine Congress PharmaJet Presents Needle-free Delivery of COVID-19 DNA Vaccine Results at World Vaccine Congress Superior immunogenicity cited with Needle-free delivery GOLDEN, Colo.–(BUSINESS

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Researchers speed identification of DNA regions that regulate gene expression

Scienmag

Jude Children’s Research Hospital scientists have developed a highly efficient method to address a major challenge in biology–identifying the genetic ‘switches’ that regulate gene expression. Credit: St. Jude Children’s Research Hospital St.

#news #biotech Sharing shears: Conserved protein segment activates molecular DNA scissors for DNA repair

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Sharing shears: Conserved protein segment activates molecular DNA scissors for DNA repair.Scientists at Tokyo Institute of Technology (Tokyo Tech) have uncovered mechanisms underlying the activation of the … Continue reading → #news

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#news #biotech DNA robots designed in minutes instead of days

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: DNA robots designed in minutes instead of days.Someday, scientists believe, tiny DNA-based robots and other nanodevices will deliver medicine inside our bodies, detect the presence of deadly … Continue reading → #news

Applied DNA Provides Preliminary Estimated Fiscal Second Quarter 2021 Revenue Range and Business Update

BioTech 365

Applied DNA Provides Preliminary Estimated Fiscal Second Quarter 2021 Revenue Range and Business Update Applied DNA Provides Preliminary Estimated Fiscal Second Quarter 2021 Revenue Range and Business Update – Anticipates Revenues in the Range of $2.5

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Applied DNA Schedules Fiscal 2021 Second Quarter Financial Results Conference Call and Webcast for Thursday, May 13, 2021

BioTech 365

Applied DNA Schedules Fiscal 2021 Second Quarter Financial Results Conference Call and Webcast for Thursday, May 13, 2021 Applied DNA Schedules Fiscal 2021 Second Quarter Financial Results Conference Call and Webcast for Thursday, May 13, 2021 STONY BROOK, N.Y.–(BUSINESS

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Applied DNA Provides Business Update on COVID-19 Diagnostics and Testing

BioTech 365

Applied DNA Provides Business Update on COVID-19 Diagnostics and Testing Applied DNA Provides Business Update on COVID-19 Diagnostics and Testing – Average Daily Testing in January 2021 to Date Up 158% Over December 2020, Driven Primarily by Scale Up in … Continue reading → Business Wire

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Scientists use DNA origami to monitor CRISPR gene targeting

Scienmag

CRISPR gene editing has transformed research, but it is not perfect, and can sometimes target unintended genes; to watch CRISPR enzymes respond to different genes, Leipzig University researchers developed a new method using DNA origami and were able to me Credit: Image courtesy of Julene Madariaga Marcos.

#news #biotech Biologists unravel full sequence of DNA repair mechanism

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Biologists unravel full sequence of DNA repair mechanism.Every living organism has DNA, and every living organism engages in DNA replication, the process by which DNA makes an … Continue reading → #news

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#news #biotech Which DNA is floating in the ditch?

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Which DNA is floating in the ditch? You pour a scoop of ditch water in the DNA scanner, and voilà: you know exactly which plants and animals the … Continue reading → #news

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Applied DNA Provides Clarification on Newly Authorized Asymptomatic Serial Screening Indication for LineaTM COVID-19 Assay Kit and Press Release Published 12 May 2021

BioTech 365

Applied DNA Provides Clarification on Newly Authorized Asymptomatic Serial Screening Indication for LineaTM COVID-19 Assay Kit and Press Release Published 12 May 2021 Applied DNA Provides Clarification on Newly Authorized Asymptomatic Serial Screening Indication for LineaTM COVID-19 Assay Kit and … Continue reading → Business Wire

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MERS DNA vaccine induces immunity, protects from virus challenge in preclinical model

Scienmag

Credit: The Wistar Institute PHILADELPHIA — (April 22, 2021) — A synthetic DNA vaccine candidate for Middle East respiratory syndrome coronavirus (MERS-CoV) developed at The Wistar Institute induced potent immune responses […].