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New Class of Antibiotic Found That Kills Deadly Drug-Resistant Superbug

AuroBlog - Aurous Healthcare Clinical Trials blog

Researchers have identified an entirely new class of antibiotic that can kill bacteria that are resistant to most current drugs.

Bacterium 180
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Probiotics increase gut bacteria diversity in extremely preterm infants

Scienmag

A new clinical study has shown that supplements of a lactic acid bacterium may have positive effects by increasing the diversity of intestinal bacteria in these infants. Extremely preterm infants can suffer from a life-threatening inflammation of the gut.

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Lumen Bioscience’s LMN-201 secures FDA fast track status to treat CDI

Pharmaceutical Technology

An investigational orally delivered biologic drug, LMN-201 is a cocktail of four therapeutic proteins that act synergistically to neutralise the C difficile bacterium and the toxin. Pivotal trials on LMN-201 are expected to commence in 2023. It is compatible with standard-of-care antibiotics.

Bacterium 130
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Intravacc gets NIAID contract for intranasal gonorrhoea vaccine development

Pharmaceutical Technology

Additionally, it will work on non-clinical toxicity (TOX) and Clinical Trial Material batch to conduct a Phase I clinical trial of the vaccine in healthy adult subjects. This trial will evaluate the safety of the vaccine and generate efficacy data. A sexually transmitted disease, gonorrhoea is caused by the NG bacteria.

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Valneva accelerates Lyme disease vaccine R&D project with Pfizer

pharmaphorum

Valneva has said it plans to accelerate research into its Lyme disease vaccine candidate VLA15, bringing forward a trial including children into the first quarter of 2021. OspA is one of the most dominant surface proteins expressed by the bacteria when present in the ticks that spread the disease.

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Vaxcyte trains its sight on a lucrative market with pneumococcal vaccine

Pharmaceutical Technology

The company says that these four serotypes represent roughly 10–15% of bacteria causing pneumococcal disease in adults. Pneumococcal vaccines are used to inoculate individuals against infections caused by the Streptococcus pneumoniae bacteria. This is in addition to its long-available pneumococcal polysaccharide vaccine PPSV23.

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Merck’s Next-Generation Pneumonia Vaccine Gets FDA Approval

XTalks

Merck has scored US Food and Drug Administration (FDA) approval for its next-generation pneumonia vaccine Vaxneuvance that covers 15 different strains of the pneumococcal bacteria that causes the infection. Both next-gen shots offer enhanced protection against bacteria that can cause pneumonia, blood infections and meningitis.