Stop the genetic presses!

Scienmag

Chemistry AND Physics Bacteriology Biochemistry Biology Cell Biology Genetics Molecular Biology

A new startup gets Takeda's backing to take complex genetic medicines 'off the shelf'

Bio Pharma Dive

Ensoma Therapeutics debuts with a lucrative alliance with the Japanese pharma and an unusual way to deliver genetic medicines into the body

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Are we genetically ‘grounded’?

Scienmag

Hebrew University identifies molecular factors that enable birds to fly, but keep the rest of us on terra firma Credit: Baruch Haimson For centuries, scientists, aeronautic designers and adventure-seekers have sought to replicate the qualities that allow birds to fly, namely wing-structure and balance.

Lilly pays $880M for Prevail, pushing further into genetic medicine

Bio Pharma Dive

The acquisition marks a significant bet by Lilly on gene therapy's potential to address tough-to-treat neurological disorders like Parkinson's disease

An AstraZeneca, Merck drug slows the return of genetic breast cancer. Will testing speed up?

Bio Pharma Dive

Study results disclosed ahead of ASCO could make Lynparza a standard "adjuvant" treatment for people with an inherited form of breast cancer — as long as they know they have it

Merck pays Seattle Genetics $1.7B as antibody cancer drugs continue comeback

Bio Pharma Dive

Merck's deal for Seattle Genetics' antibody-drug conjugate comes as Gilead agreed to acquire rival developer Immunomedics in the biotech industry's largest buyout of 2020

Japanese-European research team discovers novel genetic mitochondrial disorder

Scienmag

Biology Biochemistry Cell Biology Developmental/Reproductive Biology Genes Genetics Medicine/Health Molecular Biology Neurobiology

DNA 70

How moths find their flame – genetics of mate attraction discovered

Scienmag

Agriculture Biodiversity Biology Entomology Fertilizers/Pest Management Genetics

Simple genetic modification aims to stop mosquitoes spreading malaria

Scienmag

Infectious Emerging Diseases Biology Genes Genetics Infectious/Emerging Diseases Medicine/Health

Scientists discover a new genetic form of ALS in children

Scienmag

NIH- and USU- led study links ALS to a fat manufacturing gene and maps out a genetic therapy Credit: Courtesy of the NIH/NINDS. Medicine & Health Cell Biology Clinical Trials Gene Therapy Genes Genetics Medicine/Health Metabolism/Metabolic Diseases Neurobiology

New genetic target for blood cancer treatment

Scienmag

Medicine & Health Bioinformatics Biology cancer Cell Biology GeneticsResearchers have identified a vulnerability in some cases of acute myeloid leukaemia that could be harnessed for targeted treatment of these poor-prognosis cancers Targeting a pathway that is essential for the survival of certain types of acute myeloid leukaemia could provide a new therapy avenue for patients, the latest research has found. Researchers from the […].

Researchers show new holistic approach to genetics and plant breeding

Scienmag

Agriculture Agricultural Production/Economics Biology Biotechnology Food/Food Science Gene Therapy Genetics Molecular Biology Plant Sciences Technology/Engineering/Computer Science

The origin and uniqueness of Basque genetics revealed

Scienmag

A new study reveals that the genetic uniqueness of the Basque population is not due to its external origin in respect of other Iberian populations, but reduced contacts as of the Iron Age. Biology Genetics Population Biology

FDA approves Regeneron drug for rare, genetic form of high cholesterol

Bio Pharma Dive

The biotech set an average annual price of $450,000 for the first-of-its-kind drug, which treats a condition that affects about 1,300 people in the U.S.

New report indicates annual economic impact of human genetics/genomics

Scienmag

Grew over $200 billion since 2010, outlines new areas of promising application WASHINGTON, DC (May 19, 2021) – Human genetics and genomics contributed $265 billion to the U.S. Biology Biomedical/Environmental/Chemical Engineering Biotechnology Gene Therapy Genes Genetics Grants/Funding Health Care Policy/Ethics Science/Health and the Law

Biologists create new genetic systems to neutralize gene drives

Scienmag

Two active genetics strategies help address concerns about gene-drive releases into the wild Credit: Ana Silva In the past decade, researchers have engineered an array of new tools that control the balance of genetic inheritance.

Plant genetic engineering to fight ‘hidden hunger’

Scienmag

Agriculture Agricultural Production/Economics Biology Biotechnology Food/Food Science Genetics Molecular Biology Nutrition/Nutrients Plant Sciences

Genetics and the COVID-19 pandemic

Scienmag

ROCKVILLE, MD — With the COVID-19 pandemic still raging worldwide, members of the American Society of Human Genetics (ASHG) are working to understand how the virus spreads and infects people, why there is so much variability in susceptibility and severity, and where to look for potential therapeutics. Infectious Emerging Diseases Genetics Infectious/Emerging Diseases Medicine/Health Public Health Virology

Rare genetic disease caused by mutations in protein that controls RNA metabolism

Scienmag

Medicine & Health Biology Cell Biology Developmental/Reproductive Biology Genes Genetics Medicine/Health Molecular Biology Musculature Pediatrics

When genetic data meets marketing

Scienmag

News from the Journal of Marketing Researchers from The Wharton School of the University of Pennsylvania published a new paper in the Journal of Marketing that assesses the implications of the growth of private genetic testing for the field of marketing and evaluates ethical challenges that arise. Biology Business/Economics Genes Genetics Management Science/Operations Research Medical/Scientific Ethics Policy/Ethics Research/Development

Espresso, latte or decaf? Genetic code drives your desire for coffee

Scienmag

In a world first study of 390,435 people, University of South Australia researchers found causal genetic evidence that cardio health […]. Biology Cardiology Genes Genetics Medicine/Health

Genetic background may affect adaptions to aging

Scienmag

— How we adapt to aging late in life may be genetically influenced, according to a study led by a psychologist at the University of California, Riverside.

International research teams explore genetic effects of Chernobyl radiation

Scienmag

One study found no evidence that radiation exposure to parents resulted in new genetic changes being passed from […]. Cancer cancer Genetics Medicine/Health Public HealthIn two landmark studies, researchers have used cutting-edge genomic tools to investigate the potential health effects of exposure to ionizing radiation, a known carcinogen, from the 1986 accident at the Chernobyl nuclear power plant in northern Ukraine.

Gaps in genetic knowledge affect kiwi conservation efforts

Scienmag

A review published in Ibis examines the latest information on kiwi genetics to […]. Biology Developmental/Reproductive Biology Ecology/Environment Genetics Population BiologyKiwi are iconic birds that have been severely impacted by deforestation and predation from invasive mammals since the arrival of humans in New Zealand. The remaining kiwi can be split into 14 clusters that are now treated as separate conservation management units.

Cancer immunotherapy approach targets common genetic alteration

Scienmag

Engineered T cells can recognize and destroy cells with loss of one gene copy Credit: Elizabeth Cook Researchers developed a prototype for a new cancer immunotherapy that uses engineered T cells to target a genetic alteration common among all cancers.

Preliminary genetic link to developmental coordination disorder, dyspraxia identified

Scienmag

Medicine & Health Biology Cell Biology Genes Genetics Neurobiology Parenting/Child Care/Family PediatricsNew research by scientists at Oxford Brookes University has identified specific genes which could provide vital information about the biology of developmental coordination disorder (DCD), also known as dyspraxia. Dyspraxia is a common motor coordination condition which is estimated to affect at least one child in every classroom.

Genetic exchange discovered in anciently asexual rotifers

Scienmag

Agriculture Biodiversity Bioinformatics Biology Biotechnology Computer Science Evolution Genetics Marine/Freshwater Biology Population BiologyCredit: E.A. Mnatsakanova and O.A.

High genetic running capacity promotes efficient metabolism with aging

Scienmag

However, whether high genetic running capacity promotes more efficient metabolism with aging is not known. Adipose tissue may have a key role in healthy aging Credit: University of Jyväskylä High running capacity is associated with health and longevity.

Worldwide Rare Disease Genetic Testing Industry to 2026 – Development in Genetic Testing Technologies is Driving Growth – ResearchAndMarkets.com

BioTech 365

Worldwide Rare Disease Genetic Testing Industry to 2026 – Development in Genetic Testing Technologies is Driving Growth – ResearchAndMarkets.com Worldwide Rare Disease Genetic Testing Industry to 2026 – Development in Genetic Testing Technologies is Driving Growth – ResearchAndMarkets.com DUBLIN–(BUSINESS WIRE)–The … Continue reading → Business Wire

Genetic sleuthing reveals endangered river dolphins in Asia as different species

Scienmag

Agriculture Biology Ecology/Environment Fisheries/Aquaculture Genes Genetics Marine/Freshwater Biology Population Biology

Genetic services can overcome rare disease trial challenges: InformedDNA

Outsourcing Pharma

A leader from the genetic solutions firm explains how genetic testing and counseling can help trial teams form more beneficial connections with patients.

New way of diagnostics detects ‘undetectable’ genetic defects

Scienmag

Research provides guidance for global application Detecting hidden genetic defects by applying an existing method to an existing datasets. Biology Cell Biology Diagnostics Gene Therapy Genes Genetics Medicine/HealthResearchers at Radboud university medical center have succeeded: they showed that the ‘Expansion Hunter’ method can detect errors in the DNA that lead to repeat expansion diseases, such as the movement disorder ataxia. This result provides […].

DNA 46

Genetic gains for better grains

Scienmag

Biology Agriculture Developing Countries Food/Food Science Genes Genetics Plant SciencesCredit: © 2020 KAUST An African millet crop could be improved for growth in the dry, arid lands of Saudi Arabia by using information about its genome. Fonio is already well-adapted to this environment but has not had as much domestication as the major cereal crops, such as wheat, rice and maize. Gene targeting could […].

UCLA receives $4.8M to improve genetic disease risk estimates in diverse populations

Scienmag

million grant from The National Institutes of Health to develop methods that will improve genetic risk estimates – polygenic risk scores – for specific diseases in people from diverse populations and mixed ancestries. Medicine & Health Bioinformatics Genetics Health Care Systems/Services Medicine/Health MinoritiesLOS ANGELES (June 16, 2021) – UCLA Health will receive a $4.8

Low genetic diversity in two manatee species off South America

Scienmag

Genetic studies can help determine the conservation status of marine animals, identifying threats […]. Agriculture Biodiversity Biology Ecology/Environment Evolution Genetics Marine/Freshwater Biology Population Biology Zoology/Veterinary Science

Researchers reveal genetic predisposition to severe COVID-19

Scienmag

HSE University researchers have become the first in the world to discover genetic predisposition to severe COVID-19. Credit: S.Nersisyan et al. The results of the study were published in the journal Frontiers in Immunology.

Surprising disconnect between physical characteristics and genetic ancestry in certain

Scienmag

” Using genetic modeling, the team has found that when two populations with distinct traits combine over generations, traits of individuals within the resulting “admixed” population come to reveal very little about […]. Mathematics Biology Evolution Genetics Mathematics/Statistics Population BiologyA new study by Stanford University biologists finds an explanation for the idea that physical characteristics such as skin pigmentation are “only skin deep.”

Orphazyme’s Stocks Tumble After FDA Rejects Genetic Disease Drug

BioSpace

The FDA said that the drug, which has been studied and submitted for NPC indication, needs further data to support its use in this rare, progressive genetic disorder

Ancestry study explores COVID-19 genetic risks

Outsourcing Pharma

The online DNA network has delved into self-reported data of more than 563,000 US adults to help identify genetic risk of infection and severe outcomes.

DNA 77

Global Genetic Testing (Equipment & Consumables) Market 2021-2025: Rising Approval of Advanced Genetic Testing Products and Increasing Affordability – ResearchAndMarkets.com

BioTech 365

Global Genetic Testing (Equipment & Consumables) Market 2021-2025: Rising Approval of Advanced Genetic Testing Products and Increasing Affordability – ResearchAndMarkets.com Global Genetic Testing (Equipment & Consumables) Market 2021-2025: Rising Approval of Advanced Genetic Testing Products and Increasing Affordability – ResearchAndMarkets.com … Continue reading → Business Wire

New genetic copycatchers detect efficient and precise CRISPR editing in a living organism

Scienmag

Technology and Engineering Biology Biotechnology Cell Biology Developmental/Reproductive Biology Gene Therapy Genes Genetics

A genetic shortcut to help visualize proteins at work

Scienmag

Biology Cell Biology Genetics

New genetic clues point to new treatments for ‘silent’ stroke

Scienmag

Decade-long search uncovers genes responsible for lacunar strokes, a major cause of vascular dementia Scientists have identified new genetic clues in people who’ve had small and often apparently ‘silent’ strokes that are difficult to treat and a major cause of vascular dementia, according to research funded by the British Heart Foundation (BHF) and published in […]. Biology Cardiology Genes Genetics Medicine/Health Neurobiology Physiology Stroke