Expanding the genetic code with quadruplet codons

Scienmag

LA JOLLA, CA—One of modern biologists’ most ambitious goals is to learn how to expand or otherwise modify the genetic code of life on Earth, in order to make new, artificial life forms. Technology and Engineering code codons Expanding genetic quadruplet

Researchers discover unknown childhood genetic condition and its potential cure

Scienmag

Credit: Joseph Gleeson, UC San Diego Describing a previously unknown genetic […]. Biology Childhood condition cure discover genetic potential researchers unknown

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A new startup gets Takeda's backing to take complex genetic medicines 'off the shelf'

Bio Pharma Dive

Ensoma Therapeutics debuts with a lucrative alliance with the Japanese pharma and an unusual way to deliver genetic medicines into the body

Elsevier partners with American College of Medical Genetics and Genomics to publish Genetics in Medicine

Scienmag

Medicine & Health Collaboration Genetics Medicine/Health

Stop the genetic presses!

Scienmag

Chemistry AND Physics Bacteriology Biochemistry Biology Cell Biology Genetics Molecular Biology

Genetic cause of neurodevelopmental disorder discovered

Scienmag

Transport system of essential materials in brain cells disrupted in certain genetic developmental disorders. Biology Cell Biology Decision-making/Problem Solving Demography Developmental/Reproductive Biology Disabled Persons Genes Genetics Medicine/Health Neurobiology

Genetic analysis reveals differences in mate choice between wild and hatchery coho salmon

Scienmag

A new study of the genetic profiles of wild and hatchery coho salmon demonstrates important distinctions in how the two types of fish form mating pairs. A new study of the genetic profiles of wild and hatchery coho salmon demonstrates important distinctions in […].

Are we genetically ‘grounded’?

Scienmag

Hebrew University identifies molecular factors that enable birds to fly, but keep the rest of us on terra firma Credit: Baruch Haimson For centuries, scientists, aeronautic designers and adventure-seekers have sought to replicate the qualities that allow birds to fly, namely wing-structure and balance.

How genetic islands form among marine molluscs

Scienmag

Usually, the individuals of a population of marine species that have the potential to disperse over long distances all share a similar genetic composition. Social & Behavioral Science among form genetic Islands Marine molluscs

Lilly pays $880M for Prevail, pushing further into genetic medicine

Bio Pharma Dive

The acquisition marks a significant bet by Lilly on gene therapy's potential to address tough-to-treat neurological disorders like Parkinson's disease

Ethnically diverse research identifies more genetic markers linked to diabetes

Scienmag

Mathematics Biology Biomedical/Environmental/Chemical Engineering Biotechnology Demography Epidemiology Genetics Mathematics/Statistics Medicine/Health Policy/Ethics Public Health

Merck pays Seattle Genetics $1.7B as antibody cancer drugs continue comeback

Bio Pharma Dive

Merck's deal for Seattle Genetics' antibody-drug conjugate comes as Gilead agreed to acquire rival developer Immunomedics in the biotech industry's largest buyout of 2020

An AstraZeneca, Merck drug slows the return of genetic breast cancer. Will testing speed up?

Bio Pharma Dive

Study results disclosed ahead of ASCO could make Lynparza a standard "adjuvant" treatment for people with an inherited form of breast cancer — as long as they know they have it

Could genetics hold the key to preventing SIDS?

Scienmag

Credit: Unsplash A state-of-the-art genetic biobank could hold the key to preventing Sudden Infant Death Syndrome (SIDS), potentially saving the lives of hundreds of babies who die from the devastating condition each year.

Japanese-European research team discovers novel genetic mitochondrial disorder

Scienmag

Biology Biochemistry Cell Biology Developmental/Reproductive Biology Genes Genetics Medicine/Health Molecular Biology Neurobiology

DNA 87

New technology designed to genetically control disease-spreading mosquitoes

Scienmag

Leveraging advancements in CRISPR-based genetic engineering, researchers at the University of California San Diego have created a new system that restrains populations of mosquitoes that infect millions each year with debilitating diseases.

Genetics and the COVID-19 pandemic

Scienmag

ROCKVILLE, MD — With the COVID-19 pandemic still raging worldwide, members of the American Society of Human Genetics (ASHG) are working to understand how the virus spreads and infects people, why there is so much variability in susceptibility and severity, and where to look for potential therapeutics. Infectious Emerging Diseases Genetics Infectious/Emerging Diseases Medicine/Health Public Health Virology

The origin and uniqueness of Basque genetics revealed

Scienmag

A new study reveals that the genetic uniqueness of the Basque population is not due to its external origin in respect of other Iberian populations, but reduced contacts as of the Iron Age. Biology Genetics Population Biology

Genetic background may affect adaptions to aging

Scienmag

— How we adapt to aging late in life may be genetically influenced, according to a study led by a psychologist at the University of California, Riverside.

Simple genetic modification aims to stop mosquitoes spreading malaria

Scienmag

Infectious Emerging Diseases Biology Genes Genetics Infectious/Emerging Diseases Medicine/Health

Plant genetic engineering to fight ‘hidden hunger’

Scienmag

Agriculture Agricultural Production/Economics Biology Biotechnology Food/Food Science Genetics Molecular Biology Nutrition/Nutrients Plant Sciences

Scientists discover a new genetic form of ALS in children

Scienmag

NIH- and USU- led study links ALS to a fat manufacturing gene and maps out a genetic therapy Credit: Courtesy of the NIH/NINDS. Medicine & Health Cell Biology Clinical Trials Gene Therapy Genes Genetics Medicine/Health Metabolism/Metabolic Diseases Neurobiology

In the absence of genetic variation, asexual invasive species find new methods of adapting to their environment

Scienmag

Biology Medicine & Health genetic variation

New genetic target for blood cancer treatment

Scienmag

Medicine & Health Bioinformatics Biology cancer Cell Biology GeneticsResearchers have identified a vulnerability in some cases of acute myeloid leukaemia that could be harnessed for targeted treatment of these poor-prognosis cancers Targeting a pathway that is essential for the survival of certain types of acute myeloid leukaemia could provide a new therapy avenue for patients, the latest research has found. Researchers from the […].

Popular theory of Native American origins debunked by genetics and skeletal biology

Scienmag

A widely accepted theory of Native American origins coming from Japan has been attacked in a new scientific study, which shows that the genetics and skeletal biology “simply does not match-up”. Archaeology American Biology debunked Genetics Native origins popular skeletal theory

Genetic gains for better grains

Scienmag

Biology Agriculture Developing Countries Food/Food Science Genes Genetics Plant SciencesCredit: © 2020 KAUST An African millet crop could be improved for growth in the dry, arid lands of Saudi Arabia by using information about its genome. Fonio is already well-adapted to this environment but has not had as much domestication as the major cereal crops, such as wheat, rice and maize. Gene targeting could […].

A genetic shortcut to help visualize proteins at work

Scienmag

Biology Cell Biology Genetics

Biologists create new genetic systems to neutralize gene drives

Scienmag

Two active genetics strategies help address concerns about gene-drive releases into the wild Credit: Ana Silva In the past decade, researchers have engineered an array of new tools that control the balance of genetic inheritance.

Low genetic diversity in two manatee species off South America

Scienmag

Genetic studies can help determine the conservation status of marine animals, identifying threats […]. Agriculture Biodiversity Biology Ecology/Environment Evolution Genetics Marine/Freshwater Biology Population Biology Zoology/Veterinary Science

How moths find their flame – genetics of mate attraction discovered

Scienmag

Agriculture Biodiversity Biology Entomology Fertilizers/Pest Management Genetics

Artificial intelligence-based technology quickly identifies genetic causes of serious disease

Scienmag

Chemistry AND Physics Artificial Disease genetic identifies intelligencebased quickly technology

UofL researchers lead call to increase genetic diversity in immunogenomics

Scienmag

assistant professor in the University of Louisville Department of Biochemistry and Molecular Genetics, is leading a call to actively […]. Medicine & Health Biochemistry Genetics Infectious/Emerging Diseases Medical/Scientific Ethics Medicine/Health Molecular Biology

Researchers show new holistic approach to genetics and plant breeding

Scienmag

Agriculture Agricultural Production/Economics Biology Biotechnology Food/Food Science Gene Therapy Genetics Molecular Biology Plant Sciences Technology/Engineering/Computer Science

Genetic sleuthing reveals endangered river dolphins in Asia as different species

Scienmag

Agriculture Biology Ecology/Environment Fisheries/Aquaculture Genes Genetics Marine/Freshwater Biology Population Biology

Pfizer, Biogen, and AbbVie collaborate on genetic database

Outsourcing Pharma

The genetic exome sequence analysis partnership has created a large database linking rare protein-coding genetic variants to human health and disease.

Rare genetic variants confer largest increase in type 2 diabetes risk seen to date

Scienmag

Scientists at the University of Cambridge have identified rare genetic variants – carried by one in 3,000 people – that have a larger impact on the risk of developing type 2 diabetes than any previously identified genetic effect. Type 2 diabetes is thought to be driven in part by inherited genetic factors, but many of […]. Medicine & Health Biology Diabetes Diet/Body Weight Genes Genetics Medicine/Health Metabolism/Metabolic Diseases

FDA approves Regeneron drug for rare, genetic form of high cholesterol

Bio Pharma Dive

The biotech set an average annual price of $450,000 for the first-of-its-kind drug, which treats a condition that affects about 1,300 people in the U.S.

Rare genetic disease caused by mutations in protein that controls RNA metabolism

Scienmag

Medicine & Health Biology Cell Biology Developmental/Reproductive Biology Genes Genetics Medicine/Health Molecular Biology Musculature Pediatrics

Genetic testing cost effective for newly diagnosed GIST

Scienmag

However, because this rare type of cancer is caused by different genetic mutations, imatinib does not help all patients equally. Medicine & Health cancer Gastroenterology Genetics Internal Medicine Medicine/Health

Gaps in genetic knowledge affect kiwi conservation efforts

Scienmag

A review published in Ibis examines the latest information on kiwi genetics to […]. Biology Developmental/Reproductive Biology Ecology/Environment Genetics Population BiologyKiwi are iconic birds that have been severely impacted by deforestation and predation from invasive mammals since the arrival of humans in New Zealand. The remaining kiwi can be split into 14 clusters that are now treated as separate conservation management units.

Researchers release analysis of largest, most diverse genetic data set

Scienmag

Data demonstrates new increased diversity in genetic studies and provides new insights into population-specific diseases Researchers at the University of Maryland School of Medicine (UMSOM) and their colleagues published a new analysis today in the journal Nature from genetic sequencing data of more than 53,000 individuals, primarily from minority populations. Medicine & Health Bioinformatics Cardiology Genes Genetics Medicine/Health

Preliminary genetic link to developmental coordination disorder, dyspraxia identified

Scienmag

Medicine & Health Biology Cell Biology Genes Genetics Neurobiology Parenting/Child Care/Family PediatricsNew research by scientists at Oxford Brookes University has identified specific genes which could provide vital information about the biology of developmental coordination disorder (DCD), also known as dyspraxia. Dyspraxia is a common motor coordination condition which is estimated to affect at least one child in every classroom.

New genetic clues point to new treatments for ‘silent’ stroke

Scienmag

Decade-long search uncovers genes responsible for lacunar strokes, a major cause of vascular dementia Scientists have identified new genetic clues in people who’ve had small and often apparently ‘silent’ strokes that are difficult to treat and a major cause of vascular dementia, according to research funded by the British Heart Foundation (BHF) and published in […]. Biology Cardiology Genes Genetics Medicine/Health Neurobiology Physiology Stroke