“Soft” CRISPR may offer a new fix for genetic defects

Scienmag

Curing debilitating genetic diseases is one of the great challenges of modern medicine. Credit: Guichard/Bier Curing debilitating genetic diseases is one of […]. Technology and Engineering CRISPR defects fix genetic offer Soft

Lilly puts $700M into genetic medicine institute

Bio Pharma Dive

Building on Lilly's acquisition of Prevail Therapeutics, the Boston-based facility will use RNA- and DNA-based technologies to develop new drugs, while also supporting biotech startups in the area

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Bayer, Amgen back ReCode's plan to broaden genetic medicine's reach

Bio Pharma Dive

The two drugmakers joined a long list of investors, including Pfizer and Sanofi, that have been funding the startup’s plan to develop a new type of lipid nanoparticle technology

FDA clears AstraZeneca, Merck drug to treat some genetic breast cancers early

Bio Pharma Dive

Lynparza is the first drug targeting BRCA mutations to be approved for use in early breast cancer, a decision that could lead to more genetic testing

Genetic strategy reverses insecticide resistance

Scienmag

Technology and Engineering genetic insecticide resistance reverses StrategyInsecticides play a central role in efforts to counter global impacts of mosquito-spread malaria and other diseases, which cause an estimated 750,000 deaths each year.

Largest genetic atlas for zebrafish ‘breakthrough’ for biomedical research

Scienmag

Medical and life science researchers will benefit from the most comprehensive atlas yet of genetic data on zebrafish, newly published research suggests. Latest News Atlas Biomedical breakthrough genetic largest research ZebrafishThe atlas will help researchers to better study conditions from various types of cancer (e.g. skin cancer), heart disease, and neurodegeneration. It may help more researchers to replace mammal models in their studies. […].

Combining genetics and brain MRI can aid in predicting chances of Alzheimer’s disease

Scienmag

Simon Fraser University researchers are studying how a combination of genetics and brain MRIs may be used to predict the chances of developing Alzheimer’s disease in the future. Latest News aid Alzheimers brain chances Combining Disease Genetics MRI Predicting

Nanocarrier spray: Better crops without genetic modification

Scienmag

Researchers at the RIKEN Center for Sustainable Resource Science (CSRS) in Japan have developed a way to improve crop quality without needing to create special genetically modified plants. Space & Planetary Science crops genetic modification Nanocarrier spray

Population bottlenecks that reduced genetic diversity were common throughout human history

Scienmag

Human populations have waxed and waned over the millennia, with some cultures exploding and migrating to new areas or new continents, others dropping to such low numbers that their genetic diversity plummeted. Biology bottlenecks common diversity genetic History human population reduced

Moving away from genetic continental ancestry categories in research and medicine

Scienmag

Latest News ancestry categories continental genetic Medicine moving research

Lilly pours more money into genetic treatments for neurological diseases

Bio Pharma Dive

For $50 million, Lilly has secured rights to a technology that's meant to transport nucleic acid therapies in a way that's more targeted and better tolerated than other methods

How a virus packages its genetic material

Scienmag

Medicine & Health genetic material Packages virusRIVERSIDE, Calif. — Each simple RNA virus has a genome, its “native RNA.” This genome dictates how the virus replicates in cells to eventually cause disease.

Study reveals genetic diversity of a particularly problematic pathogen

Scienmag

Biology diversity genetic pathogen problematic reveals study

A new startup gets Takeda's backing to take complex genetic medicines 'off the shelf'

Bio Pharma Dive

Ensoma Therapeutics debuts with a lucrative alliance with the Japanese pharma and an unusual way to deliver genetic medicines into the body

Genetic links revealed between severe COVID-19 and other diseases

Scienmag

A new analysis of data from the Veterans Affairs Million Veteran Program has uncovered genetic links between COVID-19 severity and certain medical conditions that are known risk factors for severe COVID-19. Medicine & Health COVID19 diseases genetic links revealed severe

Evidence suggests cancer is not as purely genetic as once thought

Scienmag

While cancer is a genetic disease, the genetic component is just one piece of the puzzle — and researchers need to consider environmental and metabolic factors as well, according to a research review by a leading expert at the University of Alberta.

Genetic study offers new insights into DCIS biology, progression

Scienmag

The results, published today in Nature Genetics, demonstrate that […]. Latest News Biology DCIS genetic insights offers progression studyHOUSTON ? A new study led by the global Cancer Grand Challenges PRECISION team, including researchers from The University of Texas MD Anderson Cancer Center, shifts the long-held belief that all invasive breast cancers following ductal carcinoma in situ (DCIS) arise from the original DCIS lesion.

Genetic changes in Bronze Age Southern Iberia

Scienmag

Archaeology age Bronze genetic Iberia SouthernThe third millennium BCE is a highly dynamic period in the prehistory of Europe and western Asia, characterized by large-scale social and political changes.

Stop the genetic presses!

Scienmag

Chemistry AND Physics Bacteriology Biochemistry Biology Cell Biology Genetics Molecular Biology

Ionis, AstraZeneca change a key trial, fueling more questions about a genetic heart disease

Bio Pharma Dive

The partners increased the size and length of a large, ongoing study in transthyretin amyloidosis cardiomyopathy, a decision that has implications Alnylam Pharmaceuticals, which is testing two of its drugs against the disease

Insights into genetic ‘hotspots’ could produce new cancer treatment strategies

Scienmag

NEW YORK CITY, May 11, 2022 – Credit: Memorial Sloan Kettering Cancer Center NEW YORK CITY, May 11, 2022 – Many cancers contain similar genetic “hotspots” — areas of DNA that are likely to be mutated. Cancer cancer genetic hotspots insights produce strategies treatmentFor example, more than 50% of cancers contain a mutation in a gene called TP53, often within a narrow DNA […].

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Expanding the genetic code with quadruplet codons

Scienmag

LA JOLLA, CA—One of modern biologists’ most ambitious goals is to learn how to expand or otherwise modify the genetic code of life on Earth, in order to make new, artificial life forms. Technology and Engineering code codons Expanding genetic quadruplet

Elsevier partners with American College of Medical Genetics and Genomics to publish Genetics in Medicine

Scienmag

Medicine & Health Collaboration Genetics Medicine/Health

Poor diet associated with increased diabetes risk across all gradients of genetic risk

Scienmag

Genetic risk factors and diet quality are independently associated with type 2 diabetes; a healthy diet is linked to lower diabetes risk across all levels of genetic risk. Medicine & Health Diabetes diet genetic gradients Increased poor risk

Merck pays Seattle Genetics $1.7B as antibody cancer drugs continue comeback

Bio Pharma Dive

Merck's deal for Seattle Genetics' antibody-drug conjugate comes as Gilead agreed to acquire rival developer Immunomedics in the biotech industry's largest buyout of 2020

Genetic variant linked to prognosis of chronic hypersensitivity pneumonitis

Scienmag

Medicine & Health chronic genetic hypersensitivity linked pneumonitis prognosis variant

A genetic database to identify missing persons in El Salvador

Scienmag

Biology database genetic identify missing persons SalvadorEl Salvador, like other Central American countries, has suffered repression and human rights violations ever since colonial times.

Genetic cause of neurodevelopmental disorder discovered

Scienmag

Transport system of essential materials in brain cells disrupted in certain genetic developmental disorders. Biology Cell Biology Decision-making/Problem Solving Demography Developmental/Reproductive Biology Disabled Persons Genes Genetics Medicine/Health Neurobiology

BU researchers untangle the APOE4 gene, the most significant genetic risk factor for Alzheimer’s disease

Scienmag

Scientists have discovered some genetic variants that increase the risk for developing Alzheimer’s; the most well-known of these for people over the age of 65 is the APOE ?4 Latest News Alzheimers APOE4 Disease factor gene genetic researchers risk significant untangle(Boston)—Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia, affecting more than 5.8 million individuals in the U.S.

Researchers discover unknown childhood genetic condition and its potential cure

Scienmag

Credit: Joseph Gleeson, UC San Diego Describing a previously unknown genetic […]. Biology Childhood condition cure discover genetic potential researchers unknown

DrugPatentWatch named “Best of the Web” by Genetic Engineering News

Drug Patent Watch

DrugPatentWatch has been named to Genetic Engineering News‘ Best of the Web list. The review by Genetic Engineering News profile highlighted the “new training modules designed to help you find….

Bronze Age women altered genetic landscape of Orkney, study finds

Scienmag

Biology age altered Bronze finds genetic landscape Orkney study women

Lilly pays $880M for Prevail, pushing further into genetic medicine

Bio Pharma Dive

The acquisition marks a significant bet by Lilly on gene therapy's potential to address tough-to-treat neurological disorders like Parkinson's disease

Males help keep populations genetically healthy

Scienmag

This is shown by a new Uppsala University study providing in-depth knowledge of the possible long-term genetic consequences of […]. Biology Developmental/Reproductive Biology Evolution Genes GeneticsCredit: Mareike Koppik A few males are enough to fertilise all the females.

Greater diversity in genetic studies helps researchers uncover new insights

Scienmag

In genomic studies, researchers examine the DNA of a population to understand the influence of genetics on health and disease. Latest News diversity genetic greater helps insights researchers Studies uncoverUNIVERSITY PARK, Pa. —?In Though genomic studies have been common for more than a decade, most participants in these studies have been of European descent. A new study led by Lindsay Fernández-Rhodes, assistant professor of biobehavioral […].

Probe of DNA repeats reveals genetic link to schizophrenia

Scienmag

Latest News DNA genetic Link probe repeats reveals schizophreniaTORONTO – Researchers at The Hospital for Sick Children (SickKids) and Centre for Addiction and Mental Health (CAMH) have found that repeated DNA sequences in the genome may contribute to an individual’s risk of developing schizophrenia. Tandem repeats are a class of DNA sequence where two or more nucleotides, known as the building blocks of […].

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Breakthrough study uses genetic testing to evaluate risk of heart disease

Scienmag

Dignity Health in Arizona is launching the first research study in North America in which genetic testing is used to identify men and women at risk of developing heart disease based on the makeup of their DNA. Latest News breakthrough Disease evaluate genetic heart risk study testing

Multiple heart-related conditions linked to triple dementia risk, regardless of genetics

Scienmag

Having multiple conditions that affect the heart are linked to a greater risk of dementia than having high genetic risk, according to a largescale new study. Latest News conditions dementia Genetics heartrelated linked multiple risk tripleLed by Oxford University and the University of Exeter, the study is among the largest ever to examine the link between several heart-related conditions and dementia, and one of […].

Model finds COVID-19 deaths among elderly may be due to genetic limit on cell division

Scienmag

Medicine & Health among cell COVID19 deaths Division due elderly finds genetic limit modelYour immune system’s ability to combat COVID-19, like any infection, largely depends on its ability to replicate the immune cells effective at destroying the SARS-CoV-2 virus that causes the disease.

Are we genetically ‘grounded’?

Scienmag

Hebrew University identifies molecular factors that enable birds to fly, but keep the rest of us on terra firma Credit: Baruch Haimson For centuries, scientists, aeronautic designers and adventure-seekers have sought to replicate the qualities that allow birds to fly, namely wing-structure and balance.

UTHSC team receives $2 million for breast cancer genetics research

Scienmag

million from the National Cancer Institute for an advanced genetics project that could help develop targeted therapies and personalized treatment for breast cancer. Latest News breast cancer Genetics million Receives research Team UTHSCA University of Tennessee Health Science Center team has received $2.05 Liza Makowski, PhD, professor of Hematology and Oncology in the College of Medicine, is the lead investigator on the award. Developing new therapies for […].

Ethnically diverse research identifies more genetic markers linked to diabetes

Scienmag

Mathematics Biology Biomedical/Environmental/Chemical Engineering Biotechnology Demography Epidemiology Genetics Mathematics/Statistics Medicine/Health Policy/Ethics Public Health

Clue Genetics Acquires Rare Fungus Collection

BioTech 365

Clue Genetics Acquires Rare Fungus Collection Clue Genetics Acquires Rare Fungus Collection ALAMEDA ISLAND, Calif.–(BUSINESS –(BUSINESS WIRE)–Clue Genetics Inc.