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GSK gives Wave a lift with genetic medicine deal

Bio Pharma Dive

A four-year agreement between the companies comes with $170 million in cash and equity for Wave, which in recent years has dealt with clinical setbacks

Genetics 259
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Lilly and ProQR to expand genetic medicine development agreement

Pharmaceutical Technology

Eli Lilly and Company has expanded a licencing and partnership agreement with ProQR Therapeutics to discover, develop and market new genetic medicines. The post Lilly and ProQR to expand genetic medicine development agreement appeared first on Pharmaceutical Technology.

Genetics 262
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Lilly puts $700M into genetic medicine institute

Bio Pharma Dive

Building on Lilly's acquisition of Prevail Therapeutics, the Boston-based facility will use RNA- and DNA-based technologies to develop new drugs, while also supporting biotech startups in the area

Genetics 245
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FDA clears AstraZeneca, Merck drug to treat some genetic breast cancers early

Bio Pharma Dive

Lynparza is the first drug targeting BRCA mutations to be approved for use in early breast cancer, a decision that could lead to more genetic testing

Genetics 253
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Genetically modified herpes combats advanced cancers

Pharma Times

A new genetically engineered virus has delivered a one-two punch in initial phase 1 trial

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Can genetic data be a magic bullet for drug R&D?

Pharma Phorum

Ben Hargreaves finds that the vast amount of genetic data that exists today could help provide a faster, more targeted way of developing new drug candidates. The logical extension to this kind of approach is treating individual patients, with their individual genetic makeup.

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A new startup gets Takeda's backing to take complex genetic medicines 'off the shelf'

Bio Pharma Dive

Ensoma Therapeutics debuts with a lucrative alliance with the Japanese pharma and an unusual way to deliver genetic medicines into the body

Genetics 259
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Bayer, Amgen back ReCode's plan to broaden genetic medicine's reach

Bio Pharma Dive

The two drugmakers joined a long list of investors, including Pfizer and Sanofi, that have been funding the startup’s plan to develop a new type of lipid nanoparticle technology

Genetics 214
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Genetic strategy reverses insecticide resistance

Scienmag

Technology and Engineering genetic insecticide resistance reverses StrategyInsecticides play a central role in efforts to counter global impacts of mosquito-spread malaria and other diseases, which cause an estimated 750,000 deaths each year.

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Lilly pours more money into genetic treatments for neurological diseases

Bio Pharma Dive

For $50 million, Lilly has secured rights to a technology that's meant to transport nucleic acid therapies in a way that's more targeted and better tolerated than other methods

Genetics 246
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Nanocarrier spray: Better crops without genetic modification

Scienmag

Researchers at the RIKEN Center for Sustainable Resource Science (CSRS) in Japan have developed a way to improve crop quality without needing to create special genetically modified plants. Space & Planetary Science crops genetic modification Nanocarrier spray

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Fulgent Genetics acquires therapeutics development company Fulgent Pharma

Pharmaceutical Technology

Fulgent Genetics has acquired clinical-stage therapeutics development firm Fulgent Pharma for a total deal price of nearly $100m. Until 2016, Fulgent Therapeutics owned both Fulgent Pharma and Fulgent Genetics.

Genetics 130
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Genetic discovery to improve lung cancer treatment

Scienmag

Biology cancer discovery genetic improve lung treatmentLung cancer is the deadliest form of cancer, accounting for an estimated 1.8 million deaths worldwide. Credit: Edith Cowan University Lung cancer is the deadliest form of cancer, accounting for an estimated 1.8 million deaths worldwide.

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COVID-19 genetic risk variant protects against HIV

Scienmag

In addition to risk factors such as advanced age and chronic diseases, like diabetes, our genetic heritage also contributes to our individual COVID-19 severity risk. Biology COVID19 genetic HIV protects risk variant

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How a virus packages its genetic material

Scienmag

Medicine & Health genetic material Packages virusRIVERSIDE, Calif. — Each simple RNA virus has a genome, its “native RNA.” This genome dictates how the virus replicates in cells to eventually cause disease.

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Elsevier partners with American College of Medical Genetics and Genomics to publish Genetics in Medicine

Scienmag

Medicine & Health Collaboration Genetics Medicine/Health

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Merck pays Seattle Genetics $1.7B as antibody cancer drugs continue comeback

Bio Pharma Dive

Merck's deal for Seattle Genetics' antibody-drug conjugate comes as Gilead agreed to acquire rival developer Immunomedics in the biotech industry's largest buyout of 2020

Genetics 246
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Moving away from genetic continental ancestry categories in research and medicine

Scienmag

Latest News ancestry categories continental genetic Medicine moving research

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Study reveals genetic diversity of a particularly problematic pathogen

Scienmag

Biology diversity genetic pathogen problematic reveals study

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GENETIC LEVEL THERAPY FOR NEONATAL PROBLEMS

Pharma Tutor

GENETIC LEVEL THERAPY FOR NEONATAL PROBLEMS admin Fri, 01/27/2023 - 14:22 About Author KONDEPATI MALLESH BABU Priyadarshini Institute of Pharmaceutical Education and Research kondepatimallesh@gmail.com

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Alzheimer’s breakthrough: Genetic link to gut disorders confirmed

Scienmag

Social & Behavioral Science Alzheimers breakthrough confirmed disorders genetic gut LinkPeople with gut disorders may be at greater risk of developing Alzheimer’s Disease (AD).

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Evidence suggests cancer is not as purely genetic as once thought

Scienmag

While cancer is a genetic disease, the genetic component is just one piece of the puzzle — and researchers need to consider environmental and metabolic factors as well, according to a research review by a leading expert at the University of Alberta.

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Lilly pays $880M for Prevail, pushing further into genetic medicine

Bio Pharma Dive

The acquisition marks a significant bet by Lilly on gene therapy's potential to address tough-to-treat neurological disorders like Parkinson's disease

Genetics 247
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Genetic links revealed between severe COVID-19 and other diseases

Scienmag

A new analysis of data from the Veterans Affairs Million Veteran Program has uncovered genetic links between COVID-19 severity and certain medical conditions that are known risk factors for severe COVID-19. Medicine & Health COVID19 diseases genetic links revealed severe

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Scientists reveal genetic architecture underlying alcohol, cigarette abuse

Scienmag

One reason is a person’s genetic proclivity to abuse substances. […]. Latest News abuse Alcohol architecture cigarette genetic reveal scientists underlying

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Genetic changes in Bronze Age Southern Iberia

Scienmag

Archaeology age Bronze genetic Iberia SouthernThe third millennium BCE is a highly dynamic period in the prehistory of Europe and western Asia, characterized by large-scale social and political changes.

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Stop the genetic presses!

Scienmag

Chemistry AND Physics Bacteriology Biochemistry Biology Cell Biology Genetics Molecular Biology

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Ionis, AstraZeneca change a key trial, fueling more questions about a genetic heart disease

Bio Pharma Dive

The partners increased the size and length of a large, ongoing study in transthyretin amyloidosis cardiomyopathy, a decision that has implications Alnylam Pharmaceuticals, which is testing two of its drugs against the disease

Genetics 245
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Genetics and the COVID-19 pandemic

Scienmag

ROCKVILLE, MD — With the COVID-19 pandemic still raging worldwide, members of the American Society of Human Genetics (ASHG) are working to understand how the virus spreads and infects people, why there is so much variability in susceptibility and severity, and where to look for potential therapeutics. Infectious Emerging Diseases Genetics Infectious/Emerging Diseases Medicine/Health Public Health Virology

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Why early participant engagement is now a top priority in genetic disease research

Pharma Phorum

In 2016, scientists behind a study called the Resilience Project analysed genetic data from 589,000+ people and found 13 adults who carried genetic variants that should have resulted in serious – even deadly – childhood disease, but who were apparently healthy.

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Genetic background may affect adaptions to aging

Scienmag

— How we adapt to aging late in life may be genetically influenced, according to a study led by a psychologist at the University of California, Riverside.

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Researchers discover unknown childhood genetic condition and its potential cure

Scienmag

Credit: Joseph Gleeson, UC San Diego Describing a previously unknown genetic […]. Biology Childhood condition cure discover genetic potential researchers unknown

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Japanese-European research team discovers novel genetic mitochondrial disorder

Scienmag

Biology Biochemistry Cell Biology Developmental/Reproductive Biology Genes Genetics Medicine/Health Molecular Biology Neurobiology

DNA 87
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Plant genetic engineering to fight ‘hidden hunger’

Scienmag

Agriculture Agricultural Production/Economics Biology Biotechnology Food/Food Science Genetics Molecular Biology Nutrition/Nutrients Plant Sciences

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Genetic variant linked to prognosis of chronic hypersensitivity pneumonitis

Scienmag

Medicine & Health chronic genetic hypersensitivity linked pneumonitis prognosis variant

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A genetic database to identify missing persons in El Salvador

Scienmag

Biology database genetic identify missing persons SalvadorEl Salvador, like other Central American countries, has suffered repression and human rights violations ever since colonial times.

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Genetic and molecular insights into dangerous tick bite-related meat allergy revealed

Scienmag

Scientists have revealed the genetic and molecular structure of key molecules linked to the sometimes life-threatening mammalian-meat allergy brought on by tick bites. Chemistry AND Physics allergy biterelated dangerous genetic insights meat molecular revealed tick

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Expanding the genetic code with quadruplet codons

Scienmag

LA JOLLA, CA—One of modern biologists’ most ambitious goals is to learn how to expand or otherwise modify the genetic code of life on Earth, in order to make new, artificial life forms. Technology and Engineering code codons Expanding genetic quadruplet

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An AstraZeneca, Merck drug slows the return of genetic breast cancer. Will testing speed up?

Bio Pharma Dive

Study results disclosed ahead of ASCO could make Lynparza a standard "adjuvant" treatment for people with an inherited form of breast cancer — as long as they know they have it

Genetics 280
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Are we genetically ‘grounded’?

Scienmag

Hebrew University identifies molecular factors that enable birds to fly, but keep the rest of us on terra firma Credit: Baruch Haimson For centuries, scientists, aeronautic designers and adventure-seekers have sought to replicate the qualities that allow birds to fly, namely wing-structure and balance.

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Genetic cause of neurodevelopmental disorder discovered

Scienmag

Transport system of essential materials in brain cells disrupted in certain genetic developmental disorders. Biology Cell Biology Decision-making/Problem Solving Demography Developmental/Reproductive Biology Disabled Persons Genes Genetics Medicine/Health Neurobiology

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Combining genetics and brain MRI can aid in predicting chances of Alzheimer’s disease

Scienmag

Simon Fraser University researchers are studying how a combination of genetics and brain MRIs may be used to predict the chances of developing Alzheimer’s disease in the future. Latest News aid Alzheimers brain chances Combining Disease Genetics MRI Predicting

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Bronze Age women altered genetic landscape of Orkney, study finds

Scienmag

Biology age altered Bronze finds genetic landscape Orkney study women