Merck pays Seattle Genetics $1.7B as antibody cancer drugs continue comeback

Bio Pharma Dive

Merck's deal for Seattle Genetics' antibody-drug conjugate comes as Gilead agreed to acquire rival developer Immunomedics in the biotech industry's largest buyout of 2020

Plant genetic engineering to fight ‘hidden hunger’

Scienmag

Agriculture Agricultural Production/Economics Biology Biotechnology Food/Food Science Genetics Molecular Biology Nutrition/Nutrients Plant Sciences

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Biologists create new genetic systems to neutralize gene drives

Scienmag

Two active genetics strategies help address concerns about gene-drive releases into the wild Credit: Ana Silva In the past decade, researchers have engineered an array of new tools that control the balance of genetic inheritance.

Are corals genetically equipped to survive climate change?

Scienmag

Atmospheric Science Biology Climate Change Ecology/Environment Genetics Marine/Freshwater BiologyCredit: This figure appears in the publication in Molecular Biology and Evolution. In 1998, ocean temperatures soared, and the world experienced its first significant coral bleaching event.

Genetic gains for better grains

Scienmag

Biology Agriculture Developing Countries Food/Food Science Genes Genetics Plant SciencesCredit: © 2020 KAUST An African millet crop could be improved for growth in the dry, arid lands of Saudi Arabia by using information about its genome. Fonio is already well-adapted to this environment but has not had as much domestication as the major cereal crops, such as wheat, rice and maize. Gene targeting could […].

Genetic background may affect adaptions to aging

Scienmag

— How we adapt to aging late in life may be genetically influenced, according to a study led by a psychologist at the University of California, Riverside.

Genetic testing cost effective for newly diagnosed GIST

Scienmag

However, because this rare type of cancer is caused by different genetic mutations, imatinib does not help all patients equally. Medicine & Health cancer Gastroenterology Genetics Internal Medicine Medicine/Health

Sophia Genetics launches AI tool to find COVID-19 ‘unknowns’

Pharma Phorum

Swiss medical data specialist Sophia Genetics has launched a platform that will sift through data generated at more than 1,000 hospitals around the world to try to work out how the COVID-19 pandemic will evolve in the coming months and years.

Genetic adaptation to climate change is swift in crop pests

Scienmag

Agriculture Biology Climate Change Earth Science Ecology/Environment Gene Therapy Genes Genetics Parasitology

The genetics of blood: A global perspective

Scienmag

Biology Genetics Hematology Medicine/HealthWhat’s the risk of different human populations to develop a disease? To find out, a team led by Université de Montréal professor Guillaume Lettre created an international consortium to study the blood of hundreds of thousands of people worldwide. In one of the largest studies of its kind, published today in Cell, close to 750,000 […].

Seattle Genetics stays step ahead of rivals with bladder cancer data

Bio Pharma Dive

Data confirming the company's drug Padcev can extend the lives of bladder cancer patients should strengthen its position with regulators, although Immunomedics is close behind with a competing treatment

New genetic analysis method could advance personal genomics

Scienmag

Computational method capable of decoding influence of rare variants Geneticists could identify the causes of disorders that currently go undiagnosed if standard practices for collecting individual genetic information were expanded to capture more variants that researchers can now decipher, concludes new Johns Hopkins University research.

Genetic analysis links obesity to higher rheumatoid arthritis risk

Scienmag

An analysis of genetic data collected from more than 850,000 individuals of European ancestry has found a link between obesity-related genes and rheumatoid arthritis. In the Arthritis & Rheumatology analysis, investigators found an increased risk of rheumatoid arthritis when body mass index was predicted to be high based on an individual’s genetics. Biology Diet/Body Weight Eating Disorders/Obesity Genes Genetics Medicine/Health Musculature

Microbial genetics: A protean pathogen

Scienmag

The bacterium Helicobacter pylori is linked to increased risk of stomach cancer, and is genetically highly variable. A new study by researchers of Ludwig-Maximilians-Universitaet (LMU) in Munich explores the role played by this diversity in the early phase of infection in adult humans. It is estimated that about half of the world’s population is infected […]. Biology Microbiology

Genetic study of proteins is a breakthrough in drug development for complex diseases

Scienmag

Chemistry AND Physics Gene Therapy Genetics Infectious/Emerging Diseases Medicine/Health Pharmaceutical Science Public Health

Genetic background influences disease risk from single-gene variants

Scienmag

In people with a single-gene variant that puts them at high risk for heart disease, breast cancer, or colorectal cancer, the rest of the genome can alter that risk Life can change dramatically when someone learns they are genetically predisposed to a disease, such as a condition called familial hypercholesterolemia, where a mutated gene can […]. Medicine & Health Biology Breast Cancer cancer Cardiology Cholesterol Genetics Internal Medicine Metabolism/Metabolic Diseases

Merck and Seattle Genetics Ink Two New Strategic Cancer Collaborations

BioSpace

Merck is making a major investment into Bothwell, Washington-based Seattle Genetics with two strategic oncology deals

Genetic test identifies invasive lobular carcinomas that are at high risk of recurring

Scienmag

Cancer Breast Cancer cancer Clinical Trials Diagnostics Genes Genetics Gerontology Medicine/Health

After Stillbirth, New Genetic Analyses May Give Parents Answers

Scienmag

12) — Columbia researchers have uncovered an array of new genes that cause stillbirth, significantly increasing the understanding of the condition’s genetic foundations. The findings suggest that genetic analysis could be used to counsel parents who have previously experienced stillbirth and to unlock new human biology. Biology Developmental/Reproductive Biology Genes Genetics Gynecology Medicine/HealthNEW YORK, NY (Aug.

Combining genetic information with EMRs to pinpoint childhood epilepsies

Scienmag

Assessing clinical data across the lifespan identified the impact of genetic epilepsies on affected children’s lives Philadelphia, August 11, 2020 – A team of researchers at Children’s Hospital of Philadelphia (CHOP) affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) further bridged the gap between genomic information and clinical outcome data by systematically linking genetic information […].

$110m financing sets up US, Asia expansion for Sophia Genetics

Pharma Phorum

Swiss medical data specialist Sophia Genetics has raised $110 million in an oversubscribed funding round that will be used to boost its headcount and international presence and prepare to take its shares public. News R&D artificial intelligence digital financing genomics Sophia Genetics

Myriad Genetics Announces Inducement Awards

BioTech 365

14, 2020 (GLOBE NEWSWIRE) — Myriad Genetics, Inc. SALT LAKE CITY, Aug. NASDAQ: MYGN, “Myriad” or the “Company”), a global leader in molecular diagnostics and precision medicine, today announced that in connection with the previously announced appointment of Paul J. … Continue reading → GlobeNewswire

Avellino Hits the 1-Million Genetic Test Milestone

BioTech 365

–(BUSINESS WIRE)–#avagen–Avellino announced today that the company has performed over 1-million genetic and molecular diagnostic tests. On track for over 10,000 gene-based diagnostic tests performed a day MENLO PARK, Calif.–(BUSINESS

Researchers zero in on genetic connection to postpartum hemorrhage

Scienmag

CHICAGO – Researchers have identified genetic mutations that appear to protect women from severe bleeding after childbirth, a leading cause of maternal death. DNA, which carries genetic information in cells, contain biological instructions. A genetic mutation, which is a permanent […]. A preliminary study of the findings is being presented at the ANESTHESIOLOGY® 2020 annual meeting.

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WHO takes a position on genetically modified mosquitoes

The Pharma Data

Recognizing the urgent need for new tools to combat VBDs, and in the spirit of fostering innovation, WHO supports the investigation of all potentially beneficial technologies, including genetically-modified mosquitoes (GMMs).

Children with asthma could benefit from prescribing according to genetic differences

Scienmag

Results from the first trial of personalised care for children with asthma Selecting treatments according to genetic differences could help children and teenagers with asthma, according to research presented at the European Respiratory Society International Congress. [1] 1] The trial, which compares patients treated according to small genetic differences with patients treated according to existing guidelines, […].

#news #biotech Plant genetic engineering to fight hidden hunger

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Plant genetic engineering to fight hidden hunger.More than 2 billion people worldwide suffer from micronutrient malnutrition due to deficiencies in minerals and vitamins.

Scenic Biotech Enters Into Genetic Modifier Collaboration With Genentech

BioTech 365

NIH-supported scientists demonstrate how genetic variations cause eczema

Scienmag

Gene 56

COVID-19: Genetic Testing Market 2020-2024 | Rising Approval of Advanced Genetic Testing Products to boost Market Growth | Technavio

BioTech 365

LONDON–(BUSINESS WIRE)–#GeneticTestingMarket–Technavio has been monitoring the genetic testing market and it is poised to grow by USD 4.86

#news #biotech Swiss Sophia Genetics to expand globally

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Swiss Sophia Genetics to expand globally. from European Biotechnology – first and foremost in European biotech [link].

New genetic knowledge on the causes of severe COVID-19

Scienmag

A proportion of the most severe COVID-19 cases can be explained by genetic defects in the patients’ immune system. Worldwide, otherwise healthy adolescents and young people without underlying conditions are sometimes severely affected by COVID-19, with the viral infection in the worst cases quickly becoming life-threatening. But why is this happening? A world-wide consortium of […]. Infectious Emerging Diseases Infectious/Emerging Diseases Medicine/Health

Scribe Therapeutics to Collaborate With Biogen to Develop CRISPR-based Genetic Medicines for Neurological Diseases, Including Amyotrophic Lateral Sclerosis

BioTech 365

Committed to expanding treatment for underserved genetic conditions, Scribe and Biogen to collaborate on the development of novel genetic medicines for neurodegeneration ALAMEDA, Calif.–(BUSINESS

Genetics or social environment: Who wins in the influence of behaviors?

Scienmag

Researchers discovered that the social environment in which the individual develops can revert genetic effects of its behaviour, something particularly important to take into account when experiments resort to genetically modified animals. Social genetic effects occur when the […].

Cancer drug can rebalance kidney function in a devastating genetic disease

Scienmag

Biology Biochemistry Cell Biology Developmental/Reproductive Biology Genetics Medicine/Health Molecular Biology Physiology Sex-Linked Conditions Urogenital SystemResearchers at the University of Cambridge and the University of Zurich have discovered that a drug newly approved for cancer improves kidney dysfunction in a mouse model of Dent disease 2 and Lowe syndrome The study is published today in Kidney International and offers hope for the first disease-modifying treatment.

Genetic Technologies Regains Compliance with Nasdaq Stockholders Equity Requirement

BioTech 365

01, 2020 (GLOBE NEWSWIRE) — Genetic Technologies Limited (ASX: GTG; NASDAQ: GENE) (the “Company”), a leader in the development of genetic risk assessment tests, is pleased to announce that it received notification from the Listing Qualifications Department of the Nasdaq … Continue reading → GlobeNewswireMELBOURNE, Australia, Sept.

Scribe Therapeutics Unveils Fully Integrated Platform for Engineering Breakthrough CRISPR-based Genetic Medicines

BioTech 365

focused on development of novel genetic … Continue reading → Business Wire

Researchers Discover Genetic Errors and Rogue Antibodies in Cases of Severe COVID-19 Infection

XTalks

The research shows that the activity of the immune messenger type 1 interferon (IFN) protein is diminished, either by genetic mutations or an autoimmune attack by neutralizing antibodies against it, in a subset of COVID-19 patients.

#news #biotech Argentina becomes first country to approve genetically modified wheat

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Argentina becomes first country to approve genetically modified wheat.Argentina has become the first country to approve the growth and consumption of genetically modified wheat, the country’s agriculture … Continue reading → #news

Merck & Co signs multi-billion cancer drug development deal with Seattle Genetics

Pharma Phorum

Merck & Co has signed a multi-billion cancer drug development deal, which will see it investing $1 billion in partner Seattle Genetics. Seattle Genetics will receive a $600 million upfront payment and Merck will make a $1.0