article thumbnail

Risk adjusted net present value: What is the current valuation of Pharma Mar’s Ecubectedin?

Pharmaceutical Technology

According to Globaldata, it is involved in 5 clinical trials, which are ongoing. The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress. Buy the model here. It also develops RNAi candidates for the treatment of retina diseases. over FY2021.

Hormones 100
article thumbnail

Microscopic innovations in women’s health 

Drug Discovery World

This is likely in part because their byproduct, lactic acid, is known to inhibit pathogenic bacteria 25. And, in the endometrium, a decrease in Lactobacillus may affect embryo attachment and promote the growth of detrimental bacteria. This article will focus on one such area of great unmet need and promise: women’s health.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Combating antimicrobial resistance with a viable alternative to traditional antibiotics

pharmaphorum

Not to mention that traditional antibiotics are designed to attack a broad spectrum of bacteria within the host’s body. These include the harmful bacterial pathogens that cause an infection, but also the beneficial bacteria which are part of the human microbiome and are essential for good health.

Bacteria 104
article thumbnail

Iterum Therapeutics Announces Pricing of $17.5 Million Upsized Public Offering – Oct 23, 2020

The Pharma Data

The Company intends to use the net proceeds from this offering to support its planned New Drug Application submission for oral sulopenem for the treatment of uncomplicated urinary tract infections in patients with quinolone-resistant pathogens, the continued clinical development of sulopenem, and for working capital and general corporate purposes.

article thumbnail

Pfizer Acquires Amplyx Pharmaceuticals

The Pharma Data

Fosmanogepix is currently in Phase 2 clinical trials evaluating the safety and efficacy of both intravenous (IV) and oral formulations for the treatment of patients with life-threatening invasive fungal infections caused by molds, yeasts and rare molds (e.g., NEW YORK–(BUSINESS WIRE)– Pfizer Inc. and Scedosporium spp).

article thumbnail

The evolution of assays for immuno-oncology research

Drug Discovery World

The first such research dates back to 1891, when William Coley attempted to inject heat-inactivated bacteria to treat osteosarcoma. Over 250 clinical trials are currently in progress, and novel immuno-oncological treatments are already proving to be successful. This continues to be the standard of care.

article thumbnail

DALVANCE® (dalbavancin) Receives FDA Approval to Treat Acute Bacterial Skin and Skin Structure Infections in Pediatric Patients

The Pharma Data

DALVANCE is the first single-dose option administered as a 30-minute intravenous (IV) infusion for the treatment of ABSSSI caused by designated susceptible Gram-positive bacteria in pediatric patients, including infections caused by methicillin-resistant Staphylococcus aureus (MRSA). AbbVie (NYSE: ABBV) today announced that the U.S.