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Informatics helps virtual biotech bring compound to clinical trial

Drug Discovery World

Libra Therapeutics is a San Diego-based biotech focused on developing novel disease-modifying therapeutics, which restore the cellular balance that is disrupted in neurodegenerative diseases. Libra’s pipeline targets mechanisms that can mitigate protein pathology associated with CNS degenerative disorders.

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AI use in repurposing drugs for Covid-19

Drug Discovery World

We witnessed the unprecedented pace of vaccine development, fuelled by cutting-edge mRNA technology. This is exactly the type of problem that an AI-powered drug discovery engine is designed to address. There was an urgent need for quick and adaptable drug discovery in the context of a complex and poorly understood disease.

Drugs 59
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Re-assessing the risks of drug-induced arrhythmias during drug discovery

Drug Discovery World

Although such electrophysiological systems may be more predictive of potential cardiac safety and efficacy than non-functional binding assays, many apparently attractive new drugs are still being discontinued later in development. Unexpected late-stage failures in drug development are, of course, the costliest.

Drugs 52