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Informatics helps virtual biotech bring compound to clinical trial

Drug Discovery World

With no in-house laboratory space, the company works closely with multiple international contract research organisations (CROs), including Axxam, which carry out all of the Libra R&D, from compound screening assays, to in vivo pharmacokinetic/pharmacodynamic and ADME work, as well as in vitro and in vivo pre-clinical safety assessments.

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AI use in repurposing drugs for Covid-19

Drug Discovery World

This is exactly the type of problem that an AI-powered drug discovery engine is designed to address. Our goal was to quickly identify existing therapeutics that could be repurposed for Covid-19 treatment by screening a library of approved and late-stage development drugs against a disease model in our platform.

Drugs 59
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What to expect from drug discovery and development in 2023

Drug Discovery World

At the height of the pandemic, DCTs were seen as a viable alternative to keeping the engines running on clinical trials when non-critical in-person care was paused. Quantum simulations also present numerous medical applications, from fast drug design (e.g.

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Re-assessing the risks of drug-induced arrhythmias during drug discovery

Drug Discovery World

Manual patch-clamping of single cells has become a mainstay of functional electrophysiology, often used to follow up after novel hit compounds are identified by non-functional fluorescence or ligand binding methods, which are considerably higher in their throughput. He has a D.Phil. in physiology from Oxford University.

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