Drug Discovery World

MAY 11, 2023

First, products containing undesired proteases can impair drug stability, either by degrading the drug itself or by degrading stabilising excipients of the drug formulation, which ultimately diminishes the drug’s durability. In the case of therapeutics, the aim is usually to avoid patients’ immune responses.

Production 52

Production Gene Protein Vaccination 52

Drug Discovery World

FEBRUARY 8, 2023

This helps ensure a high concentration of loaded capsids and adequate removal of impurities, such as host cell proteins and DNA. In AAV therapeutics, empty capsids are those that are not packaged with the therapeutic DNA. Robustness: to be able to tolerate matrix effects (type of buffer, residual contaminants, ionic strength, etc.)

Gene Therapy 52

Gene Therapy Gene Antibody Production 52

XTalks

SEPTEMBER 14, 2020

“Vaccine Nationalism” Could Prove the Undoing of COVID-19 Containment. It was recently reported that the addition of an adjuvant to their vaccine led to enhanced immune responses that exceeded responses in convalescent serum from symptomatic COVID-19 patients. That’s if Russia doesn’t get its hands on it first.

Vaccination 92

Vaccination Vaccine Antibody Life Science 92