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The path to improved safety of gene-based products

Drug Discovery World

Gene-based therapeutics and vaccines hold immense potential for more efficient and personalised treatment and prevention of complex diseases. In these cases, injection of the viral vector vaccines induced the production of antibodies recognising platelet factor 4 (PF4) found on patients’ platelets 1.

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Regeneron’s Antibody Drug Becomes First Approved Treatment for Ebola

XTalks

Related: First Ebola Vaccine Cleared by European Commission. “We Ebola virus is transmitted through direct contact with blood, body fluids and tissues of infected people or wild animals, as well as with surfaces and materials – such as bedding and clothing – contaminated with these fluids. Targeted Antiviral Treatment.

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STAT+: Pharmalittle: Moderna must face patent claims over its Covid-19 vaccine; Pfizer and BioNTech testing combo Covid and flu shot

STAT News

… A Delaware federal court refused to throw out patent infringement claims brought by Arbutus Biopharma and Genevant Sciences against Moderna over its sale of Covid-19 vaccine doses to the U.S.  Genevant and Arbutus sued Moderna in February, seeking royalties from Moderna’s sale of its Covid-19 vaccine.

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Optimising AAV capsid purification through improved analytics

Drug Discovery World

First, empty capsids may have the potential to induce an elevated immune response to high concentrations of viral particles. Partially-filled capsids may also be present, and contain packaged process-related impurities or truncated genetic material. What makes an ideal AAV analytics tool for process development?

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COVID-19 Pandemic Coverage

XTalks

Vaccine Nationalism” Could Prove the Undoing of COVID-19 Containment. Tension is mounting as nations big and small jockey around industry to ensure they are first in line to access a vaccine, should one prove to be successful against COVID-19. Moderna’s COVID-19 Vaccine. The price of that prize is incalculable.