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Cell-penetrating peptides as a delivery system for oligonucleotides

Drug Discovery World

Emerging as a new treatment option in rare and orphan disease areas, oligonucleotide therapeutics have matured into a drug class with a broad indication spectrum. These peptides typically contain up to 30 amino acids and can be cationic, amphipathic or both. Here, Bachem explores the science behind this approach. Nanoparticles 6.