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Bioavailability Related Topics 
Outsourcing Pharma
JUNE 14, 2021
With bioavailability challenges a frequent frustration for drug developers, one research outfit suggests a technique that could reduce the headaches. Bioavailability Challenge
Fierce Pharma
JULY 12, 2022
Take 2: Hanmi relaunches liver drug after boosting bioavailability. ntaylor. Tue, 07/12/2022 - 08:58
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BioTech 365
JANUARY 26, 2022
Global Drug Bioavailability Enhancement Summit 2022: Two Day Online Program – May 16-17, 2022 – ResearchAndMarkets.com Global Drug Bioavailability Enhancement Summit 2022: Two Day Online Program – May 16-17, 2022 – ResearchAndMarkets.com DUBLIN–(BUSINESS WIRE)–The “2022 Global Drug Bioavailability Enhancement Summit” … Continue reading → Business Wire
BioTech 365
MARCH 28, 2022
Valbiotis Announces the Positive Results of Its Clinical Study on the Bioavailability and Mode of Action of TOTUM•070, Against Hypercholesterolemia Valbiotis Announces the Positive Results of Its Clinical Study on the Bioavailability and Mode of Action of TOTUM•070, Against Hypercholesterolemia … Continue reading → Business Wire
Outsourcing Pharma
AUGUST 8, 2022
The pharmaceutical company has forged a partnership with the nanotechnology specialist to use nanoparticle tech and formulation to advance its products. Drug Delivery
BioTech 365
OCTOBER 5, 2021
Global Peptide Therapeutics Markets, 2021-2026 – Increase Bioavailability of Drugs and Broaden Application of Peptides Therapeutics – ResearchAndMarkets.com Global Peptide Therapeutics Markets, 2021-2026 – Increase Bioavailability of Drugs and Broaden Application of Peptides Therapeutics – ResearchAndMarkets.com DUBLIN–(BUSINESS WIRE)–The “Global Peptide … Continue reading → Business Wire
BioTech 365
AUGUST 17, 2021
Alzamend Neuro Announces It Has Contracted With Altasciences to Conduct a Phase I Relative Bioavailability Study for AL001 for Dementia Related to Alzheimer’s Disease in September 2021 Alzamend Neuro Announces It Has Contracted With Altasciences to Conduct a Phase I … Continue reading → Business Wire
BioTech 365
JULY 1, 2022
Microsize Launched as Independent Pharma Services Company Microsize Launched as Independent Pharma Services Company Meets the Growing Need for US-Based API Solubility and Bioavailability Enhancement Services QUAKERTOWN, Pa.–(BUSINESS
BioTech 365
JULY 14, 2022
Biora Therapeutics Shares Preclinical Data on Oral Delivery of Biologics at Controlled Release Society 2022 Biora Therapeutics Shares Preclinical Data on Oral Delivery of Biologics at Controlled Release Society 2022 Demonstrates OBDS Device Performance and Bioavailability in Animal Models SAN … Continue reading → GlobeNewswire
Scienmag
MAY 21, 2022
By measuring the maximum concentration over time, the researchers found bioavailability of vitamin D […]. According to a new study that will be presented today (Saturday 21 May at 12:00 noon CEST) at the 24th European Congress of Endocrinology in Milan, Italy on vitamin D food fortification working better with water and milk than in juice. Latest News absorbing efficient finds milk study Vehicles vitamin water
BioTech 365
MARCH 25, 2021
NASDAQ: EWTX), a clinical-stage biopharmaceutical company focused on developing orally bioavailable, small molecule therapies for rare muscle disorders, announced … Continue reading → Business Wire
BioTech 365
MARCH 10, 2021
Venatorx Pharmaceuticals Expands Anti-Infective Portfolio with HBV Candidate Venatorx Pharmaceuticals Expands Anti-Infective Portfolio with HBV Candidate VNRX-9945 Selected as 3rd Generation Hepatitis B Virus Orally Bioavailable CpAM; Clinical Trial Application and Phase 1 Planned for Second Quarter 2021 MALVERN, Pa.–(BUSINESS
XTalks
DECEMBER 5, 2022
Clinical-stage biotech company PureTech Health has announced it has developed a new oral CBD therapeutic candidate with improved bioavailability and tolerability, which could expand use of the CBD prodrug in a wide range of indications and age groups.
BioTech 365
SEPTEMBER 28, 2021
inhibitor, ART4215, is the first selective, orally bioavailable, small molecule inhibitor of the Pol? Artios Doses First Patient in Phase 1/2a Study of Pol? Inhibitor ART4215 Artios Doses First Patient in Phase 1/2a Study of Pol? Inhibitor ART4215 Pol? polymerase … Continue reading → GlobeNewswire
Pharma Mirror
APRIL 8, 2022
CellCentric is developing inobrodib, an orally bioavailable drug that is transitioning into Phase II clinical trials in multiple indications.
Camargo
FEBRUARY 10, 2021
The results of the population analysis reveal the average relative bioavailability of the test to reference. The comparison of relative bioavailability based on simulated data then indicates if BE can be achieved.
Roots Analysis
FEBRUARY 20, 2022
In fact, it has been observed that around 40% of the pharmaceutical products approved by regulatory organizations exhibit poor bioavailability / solubility. Further, every year, poor bioavailability is one of the prime reasons that leads to failure in obtaining approval authorization.
Pharmaceutical Technology
NOVEMBER 18, 2022
It was specifically designed to provide targeted and sustained BTK protein inhibition by optimising bioavailability, selectivity, and half-life. The European Commission (EC) has approved BeiGene’s Brukinsa (zanubrutinib) to treat chronic lymphocytic leukaemia (CLL) in adult patients.
Camargo
DECEMBER 22, 2021
Clinical pharmacology may also involve comparative bioavailability analyses, which are generally required for drug formulation bridging studies, to demonstrate bioequivalence.
Pharmaceutical Technology
NOVEMBER 24, 2022
Given our expertise in the provision of IVMT studies to investigate the absolute bioavailability of oral drug molecules, we have developed a particular focus in recent years on the conduct of integrated IVMT/ADME studies.
Camargo
SEPTEMBER 30, 2021
While formulation changes for an ongoing program may improve stability, they might also impact the bioavailability, toxicokinetic profile, or toxicology – potentially rendering all previous work void and irrelevant and costing the program money and time.
Pharmaceutical Technology
AUGUST 30, 2022
Reduced solubility and low bioavailability affect a huge number of solid drug products, especially tablet formulations on the market.
The Pharma Data
DECEMBER 3, 2020
SOL-578 is a best-in-class checkpoint kinase 1 (Chk1) inhibitor featuring high kinase selectivity and oral bioavailability which targets the DNA Damage Response (DDR) network. TAIPEI , Dec. 4, 2020 /PRNewswire/ — PharmaEngine, Inc.
Camargo
AUGUST 22, 2021
3.1.1: Bioavailability Study Reports. When a submission is sent through the FDA’s Electronic Submissions Gateway (ESG), it goes through an automated check of many validation rules, as specified in the Electronic Common Technical Document (eCTD) submission standards guidance.
The Pharma Data
JANUARY 7, 2021
While oral delivery route (62%) is still the most prevalent amongst marketed drug products, alternative adminstrations such as injection (22%), cutaneous, mucosal, inhalation, and others are making up a greater percentage as the industry works to improve bioavailability and subsequent efficacy.
Roots Analysis
MARCH 2, 2022
However, it is important to highlight that there are still several challenges which need to be addressed in order to develop biologic drugs capable of effectively being administered via the oral route without undergoing significant losses in specificity and / or bioavailability.
Roots Analysis
MARCH 1, 2022
This can be attributed to ease of delivery, increased bioavailability and by-pass of first-pass metabolism offered by this type of route of administration.
Camargo
JULY 8, 2021
In June, the FDA issued an updated (draft) guidance titled “ Sponsor Responsibilities—Safety Reporting Requirements and Safety Assessment for IND and Bioavailability/Bioequivalence Studies.”
Pharmaceutical Technology
AUGUST 10, 2022
Catale n t has signed an agreement for the acquisition of full-service specialty Contract Development and Manufacturing Organization (CDMO) Metrics Contract Services for $475m from Mayne Pharma.
Roots Analysis
MARCH 13, 2022
Furthermore, excipients play a critical role in biologics development by enhancing the solubility and bioavailability, controlling pH and tonicity of the active pharmaceutical ingredients (APIs).
XTalks
FEBRUARY 25, 2022
In terms of its nutritional profile, EverPro is high in bioavailable protein, low in carbohydrates, contains just half a gram of sugar per 100 grams and is free from cholesterol, dairy and soy.
Pharmaceutical Technology
SEPTEMBER 23, 2022
GlobalData anticipates CyclASol to be positioned as the superior cyclosporine due to its favorable tolerability profile and better bioavailability, with the potential to capture market share from other cyclosporine-based therapies.
Pharma Phorum
AUGUST 19, 2022
Among these still in development, Glenmark’s orally active GRC17536 cleared a phase 2a study in diabetic neuropathy but has bioavailability issues that have held up a phase 3 programme.
Pharma Phorum
NOVEMBER 9, 2022
He continued: “We are impressed by the potential of NRG’s small molecules as orally-bioavailable and brain-penetrant treatments and look forward to working with the team to move the programmes through IND-enabling studies.”.
CATO Research
SEPTEMBER 3, 2020
Compliance Policy for the Quantity of Bioavailability and Bioequivalence Samples Retained Under 21 CFR 320.38(c) By Dieanira Erudaitius, PhD, RAC, Regulatory Scientist, Regulatory Affairs at CATO SMS. Special Interest Guidances/Information. Date Posted.
Pharma Phorum
JULY 22, 2021
The company said other companies were also looking at the orally bioavailable drug, but Pfizer emerged as an ideal partner for ARV-371.
Pharma Phorum
NOVEMBER 22, 2021
The drug, which is given by subcutaneous injection once a day, looks set to beat a rival antiviral therapy for HDV from Eiger Biopharmaceuticals to the US market, although the latter is orally bioavailable so could prove to be a potent competitor if it reaches the market.
The Pharma Data
DECEMBER 29, 2020
Cybin is developing technologies and delivery systems, aiming to improve bioavailability, to potentially achieve the desired medicinal effects of psychedelics at low dosage levels. 30, 2020 01:00 UTC. TORONTO–( BUSINESS WIRE )– Cybin Inc. (
Delveinsight
AUGUST 25, 2020
The drug is directly delivered to lungs via inhalation to achieve high local exposures, and address the concerns of low oral bioavailability linked to niclosamide. . Novartis’s Spartalizumab Combo Fails To Meet The Primary Goal In The Melanoma Trial.
CATO Research
SEPTEMBER 3, 2020
Compliance Policy for the Quantity of Bioavailability and Bioequivalence Samples Retained Under 21 CFR 320.38(c) By Dieanira Erudaitius, PhD, RAC, Regulatory Scientist, Regulatory Affairs at CATO SMS. Special Interest Guidances/Information. Date Posted.
CATO Research
SEPTEMBER 3, 2020
Compliance Policy for the Quantity of Bioavailability and Bioequivalence Samples Retained Under 21 CFR 320.38(c) By Dieanira Erudaitius, PhD, RAC, Regulatory Scientist, Regulatory Affairs at CATO SMS. Special Interest Guidances/Information. Date Posted.
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