Scienmag

JULY 7, 2025

Cutting-edge research demonstrates that certain siderophores not only serve as bioavailable iron carriers for anammox bacteria but also act as metabolic regulators that modulate enzyme assembly and nitrogen removal efficacy. In contrast, Candidatus Jettenia employs a reductive mechanism to process siderophore-bound iron.

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Bacteria Bioavailability Engineer Regulation 59

Scienmag

JUNE 18, 2025

By sequestering iron from competing microbes, Pandorabactins effectively reduce the bioavailability of iron, thereby suppressing rival bacterial populations. Subsequent assays revealed that these siderophores can inhibit the growth of cohabiting bacterial genera such as Pseudomonas , Mycobacterium , and Stenotrophomonas.

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Bacteria Genomics Genome Production 59

Scienmag

JUNE 21, 2025

Furthermore, iterative chemical optimization enhanced the specificity and bioavailability of lead compounds, ensuring their suitability for in vivo applications and eventual clinical trial progression. Extensive cytotoxicity assays revealed minimal adverse effects at therapeutic concentrations, highlighting a favorable safety profile.

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Drugs Genetics Protein DNA 59

Scienmag

JUNE 26, 2025

Published in the European Journal of Nutrition, this peer-reviewed work marks a significant milestone in nutritional cardiovascular research, encouraging further investigation and clinical trials to better define optimal vitamin K1 dosing, bioavailability, and its interactions with other nutrients.

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Bioavailability Protein Research Clinical Trials 52

PharmTech

JUNE 24, 2025

Fortunately, novel formulation strategies and technologies are reshaping drug development, from overcoming oral solid dose (OSD) challenges to advancing bioavailability and redefining traditional drug-likeness criteria.

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Manufacturing Bioavailability Development Drugs 40

Bio Pharma Dive

JUNE 23, 2025

The pharmaceutical industry is exploring alternatives such as oral formulations, sublingual dissolvables, and transdermal methods to improve sustainability and patient convenience, though scientific hurdles like bioavailability remain.

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Gene Therapy Drugs Gene Life Science 130

Pharmaceutical Technology

JUNE 16, 2025

The trial data indicated dose-dependent protein production at the site without systemic bioavailability. Ethris’ platform technologies have shown favourable results in Phase I trials for ETH47, a candidate targeting asthma exacerbations through nasal administration.

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Pharmaceutical Technology

JULY 11, 2025

Sectors Sections Clinical Trials Drug Manufacturers Therapy Area Pricing and Market Access Latest FDA gives TSND-201 breakthrough therapy designation for PTSD CTO East Coast 2025: Global oncology cell therapy market to hit $25bn by 2031 Lupin and Zentiva in licence and supply deal for Certolizumab Pegol Themes Sections Artificial Intelligence Cloud (..)

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Clinical Trials Clinical Trials Trials Gene Therapy 130

Pharmaceutical Technology

JULY 7, 2025

Listen to episode one below: While the excitement to commence clinical trials often motivates tight deadlines in R&D, sufficient time is critical for understanding and optimizing an API’s bioavailability, stability, toxicology, and excipient compatibility.

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Clinical Trials Clinical Trials Manufacturing Packaging 130

PharmTech

JUNE 27, 2025

The program is designed to fast-track early development of drug formulations, especially to combat bioavailability and solubility challenges. Accelerating drug development In other Aenova news, the company launched its Aenovation program for the acceleration of drug development in May 2025 (2).

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Manufacturing Development Vaccination Vaccine 59

Scienmag

JULY 11, 2025

Pharmaceuticals, personal care products, pesticides, and industrial chemicals frequently adsorb onto plastic surfaces, altering their bioavailability and persistence. These plastics exhibit heterogeneous surface chemistries that attract metal ions and organic compounds, mediating their transport and bioavailability.

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Contamination Bioavailability Production Engineer 64

Scienmag

JULY 16, 2025

Despite its abundance in the atmosphere, nitrogen’s bioavailability in soil is often limited, imposing a significant challenge to global agriculture. Nitrogen, a critical macronutrient, is fundamental for plant growth and development, serving as a building block of amino acids, nucleic acids, and chlorophyll.

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Gene Expression Gene Regulation Bioavailability 75

Pharmaceutical Technology

JULY 11, 2025

Sectors Sections Clinical Trials Drug Manufacturers Therapy Area Pricing and Market Access Latest FDA gives TSND-201 breakthrough therapy designation for PTSD CTO East Coast 2025: Global oncology cell therapy market to hit $25bn by 2031 Lupin and Zentiva in licence and supply deal for Certolizumab Pegol Themes Sections Artificial Intelligence Cloud (..)

Gene Therapy 130

Gene Therapy Manufacturing Marketing Clinical Trials 130

Pharmaceutical Technology

JULY 11, 2025

Sectors Sections Clinical Trials Drug Manufacturers Therapy Area Pricing and Market Access Latest FDA gives TSND-201 breakthrough therapy designation for PTSD CTO East Coast 2025: Global oncology cell therapy market to hit $25bn by 2031 Lupin and Zentiva in licence and supply deal for Certolizumab Pegol Themes Sections Artificial Intelligence Cloud (..)

Gene Therapy 130

Gene Therapy Clinical Trials Clinical Trials Manufacturing 130

Pharmaceutical Technology

JULY 11, 2025

Sectors Sections Clinical Trials Drug Manufacturers Therapy Area Pricing and Market Access Latest FDA gives TSND-201 breakthrough therapy designation for PTSD CTO East Coast 2025: Global oncology cell therapy market to hit $25bn by 2031 Lupin and Zentiva in licence and supply deal for Certolizumab Pegol Themes Sections Artificial Intelligence Cloud (..)

Gene Therapy 130

Gene Therapy Manufacturing Clinical Trials Marketing 130

XTalks

NOVEMBER 6, 2024

The stable gel matrix holds multiple ingredients, offering targeted release and enhanced bioavailability while optimizing patient experience. Gelteq centers its technology on a proprietary, customizable gel platform designed for precise drug delivery, supporting prescription drugs, nutraceuticals, pet care and sports supplements.

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Drug Delivery Drugs Bioequivalency Bioavailability 104

Scienmag

JUNE 27, 2025

If aerosols naturally facilitate reactions like urea synthesis, they might contribute directly to the inventory of bioavailable nitrogen compounds, thereby influencing ecological and evolutionary dynamics in ways previously unappreciated. The technological ramifications of this discovery are equally compelling.

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RNA DNA Production Research 59

Scienmag

JULY 5, 2025

The interaction between dissolved mercury species and biogeochemical cycles modulates mercury bioavailability and methylation—the conversion to methylmercury, a highly toxic neurotoxin that bioaccumulates in marine food webs. In tandem with understanding sources, the study sheds light on mercury cycling processes within the ocean itself.

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Contamination Research Bioavailability Scientist 45

Scienmag

JUNE 23, 2025

Legumes, through their symbiotic relationship with nitrogen-fixing bacteria called rhizobia, enrich the soil with bioavailable nitrogen, a crucial nutrient for plant growth. By cycling different crops, especially alternating between legumes and cereals, farmers can naturally boost soil fertility and curb reliance on synthetic fertilizers.

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Production Bioavailability Research Bacteria 92

Scienmag

JUNE 6, 2025

This strain survives the digestive tract, supporting not only the preservation of fermented foods but also generating bioactive peptides and amino acids that are more bioavailable compared to intact proteins in pulses.

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Protein Bioavailability Research Regulation 52

PharmTech

JULY 4, 2025

Sustained and targeted delivery products are helping reduce the dosing frequency by overcoming ocular barriers and increasing bioavailability. Drops do not maintain good bioavailability and are relatively quickly flushed out by nasolacrimal drainage,” explains Jeffrey S. There are limitations to their effectiveness, however.

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Manufacturing Bioavailability Drug Delivery FDA Approval 64

Scienmag

JULY 4, 2025

In unfertilized, high-yielding fields, root microbiomes were notably enriched with nitrogen-fixing bacteria, such as members of Rhizobium and related taxa, capable of converting atmospheric nitrogen into bioavailable forms.

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Bacteria Engineer Gene Sequencing Genotype 89

Scienmag

JULY 4, 2025

Both methodologies revolve around flushing contaminants out of contaminated sites, reducing bioavailability, and ultimately restoring soil functionality. Flushing, in contrast, generally involves in-situ processes where fluids are systematically introduced into the subsurface to mobilize and extract pollutants.

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Contamination Bioavailability Research Licensing 59

Roots Analysis

FEBRUARY 15, 2023

Moreover, it is a well-established fact that the systemic / local absorption and distribution of a therapeutic intervention is directly proportional to its bioavailability. Technology evaluation framework provides a value addition matrix for bioavailability enhancement approaches currently employed by industry stakeholders.

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Bioavailability In-Vivo Marketing Drugs 52

Outsourcing Pharma

JUNE 14, 2021

With bioavailability challenges a frequent frustration for drug developers, one research outfit suggests a technique that could reduce the headaches.

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Bioavailability Development Drugs Research 57

Pharmaceutical Technology

SEPTEMBER 17, 2024

The partnership will see AI-enabled screening used to address bioavailability issues with Equillium’s cytokine-targeting peptide.

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Bioavailability 130

Pharmaceutical Technology

JANUARY 13, 2025

Nano milling is a vital technique for developing fine particle-sized drug formulations and improving bioavailability of water-soluble APIs.

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Bioavailability Development Drugs 130

Pharmaceutical Technology

JUNE 9, 2023

The water-free formulation of the investigational drug increases residual time on the surface of the eye and improves bioavailability in the target tissues to release the complete potential of cyclosporine A. CyclASol is topical anti-inflammatory and immunomodulating ophthalmic drug solution containing 0.1%

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FDA Approval Bioavailability Containment Drugs 246

BioPharma Reporter

JUNE 22, 2023

New research reveals the bioavailability of both CBD and THC components of hemp, is higher when delivered in certain oil carriers, and describes how some CBD is converted into THC in the body.

Bioavailability 52

Bioavailability Research Development 52

Pharmaceutical Technology

APRIL 4, 2024

Discover Lipocine Inc's innovative patent for bioavailable solid state esters to treat testosterone deficiency in mammals. Learn about the unique pharmaceutical composition and release characteristics for optimal delivery and efficacy.

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Bioavailability 130

Outsourcing Pharma

JULY 9, 2024

dsm-firmenich has announced the launch of CBtru â an advanced formulated cannabidiol (CBD) drug product intermediate designed for oral solid delivery formats.

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Bioavailability Development Drugs Production 81

Pharmaceutical Technology

AUGUST 22, 2024

Discover Amneal Pharmaceuticals' innovative gastroretentive tablet patent, enhancing drug bioavailability and sustained release of pyridostigmine bromide for improved patient outcomes.

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Bioavailability Drugs 100

Pharma Mirror

APRIL 8, 2022

CellCentric is developing inobrodib, an orally bioavailable drug that is transitioning into Phase II clinical trials in multiple indications. Both have stellar experience and track records in oncology research and development.

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Bioavailability Clinical Trials Clinical Trials Development 130

BioTech 365

JANUARY 26, 2022

Global Drug Bioavailability Enhancement Summit 2022: Two Day Online Program – May 16-17, 2022 – ResearchAndMarkets.com Global Drug Bioavailability Enhancement Summit 2022: Two Day Online Program – May 16-17, 2022 – ResearchAndMarkets.com DUBLIN–(BUSINESS WIRE)–The “2022 Global Drug Bioavailability Enhancement (..)

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Bioavailability Drugs 40

Drug Patent Watch

JUNE 17, 2024

Here are some key approaches with examples: New Formulations One common strategy is to develop and patent new formulations of the existing drug compound to provide benefits like reduced dosing frequency, easier administration, improved bioavailability, or reduced side effects. […] Source

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Bioavailability Drugs Development 105

BioTech 365

OCTOBER 5, 2021

Global Peptide Therapeutics Markets, 2021-2026 – Increase Bioavailability of Drugs and Broaden Application of Peptides Therapeutics – ResearchAndMarkets.com Global Peptide Therapeutics Markets, 2021-2026 – Increase Bioavailability of Drugs and Broaden Application of Peptides Therapeutics – ResearchAndMarkets.com DUBLIN–(BUSINESS (..)

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Bioavailability Marketing Drugs 40

BioTech 365

APRIL 30, 2021

Outlook on the Microencapsulation Global Market to 2027 – Need to Reduce Capsule Size and Increase Bioavailability Presents Opportunities – ResearchAndMarkets.com Outlook on the Microencapsulation Global Market to 2027 – Need to Reduce Capsule Size and Increase Bioavailability Presents Opportunities … Continue reading → (..)

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